{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T14:22:49Z","timestamp":1781360569990,"version":"3.54.1"},"reference-count":22,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"11","license":[{"start":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T00:00:00Z","timestamp":1647216000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,14]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic small-vessel vasculitis characterized by the presence of asthma and eosinophilia. Because cerebral aneurysm formation induced by EGPA is a rare occurrence, there is no established treatment strategy for this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 67-year-old female who was diagnosed with idiopathic eosinophilia 3 months ago developed de novo fusiform aneurysms in the left vertebral, left internal carotid, and bilateral superficial temporal arteries, as noted during a regular follow-up examination of a convexity meningioma. Pathological examination of the resected superficial temporal artery revealed eosinophilic granulomas, which led to the diagnosis of EGPA, as well as EGPA-induced aneurysm formation. As the partially thrombosed vertebral artery fusiform aneurysm enlarged, the compression of the medulla oblongata occurred despite intensive immunosuppressive therapy for 1 year. The patient underwent flow diversion therapy administered using the pipeline embolization device, resulting in complete disappearance of the aneurysm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Considering that the entire circumference of the aneurysmal wall is affected by necrotizing vasculitis, flow diverter therapy would be a reasonable and efficient approach for the treatment of EGPA-related aneurysms in cases in which the patient is nonresponsive to immunosuppressants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case21701","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T03:07:43Z","timestamp":1647227263000},"source":"Crossref","is-referenced-by-count":3,"title":["Flow diverter therapy for immunosuppressant-resistant vertebral artery fusiform aneurysm due to eosinophilic granulomatosis with polyangiitis: illustrative case"],"prefix":"10.3171","volume":"3","author":[{"given":"Tetsuya","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Sendai Medical Center, Sendai, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Sakata","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Sendai Medical Center, Sendai, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Ezura","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Sendai Medical Center, Sendai, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Sendai Medical Center, Sendai, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinari","family":"Osada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Hospital Organization Sendai Medical Center, Sendai, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teiji","family":"Tominaga","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"9357","key":"b1","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/S0140-6736(03)12518-4","article-title":"Churg-Strauss syndrome","volume":"361","author":"Noth I","year":"2003","unstructured":"Noth I, Strek ME, Leff AR. 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