{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:38:22Z","timestamp":1770352702968,"version":"3.49.0"},"reference-count":22,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"24","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The best treatment option for giant intracranial aneurysms (GIAs) is still debated. The authors report a case of a giant thrombosed cavernous carotid artery (CCA) aneurysm for which two sessions of flow diverter (FD) placement failed, leading to bilateral blindness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 66-year-old man presented to an outside center with a history of rapid-onset right-sided retro-orbital pain, visual deterioration, and restricted eye movements associated with headache, vomiting, and diminished sensations on the right side of the face. He was diagnosed with an unruptured thrombosed giant CCA aneurysm and was treated twice with unsuccessful FDs. At follow-up, he developed blindness in both eyes. After 1.5 years, he presented to the authors\u2019 institution with headache, vomiting, and epistaxis, for which he underwent high-flow external carotid artery\u2013M2 segment of the middle cerebral artery bypass grafting using the radial artery as a conduit and ligation of the internal carotid artery in the neck without any added neurological deficits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>This dreadful complication of bilateral blindness after being treated with repeated unsuccessful FDs has not been reported in the literature. It could have been avoided if microsurgery had been the primary modality of treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case22352","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T02:56:01Z","timestamp":1670813761000},"source":"Crossref","is-referenced-by-count":4,"title":["Bilateral blindness following flow diverter placement in a giant thrombosed cavernous carotid aneurysm: illustrative case"],"prefix":"10.3171","volume":"4","author":[{"given":"Basant K.","family":"Misra","sequence":"first","affiliation":[{"name":"Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Medical Research Center, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alay V.","family":"Khandhar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Medical Research Center, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reema","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Gamma Knife Radiosurgery, P.D. Hinduja National Hospital and Medical Research Center, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"6","key":"b1","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1227\/NEU.0b013e31822bb8a6","article-title":"Giant intracranial aneurysms: evolution of management in a contemporary surgical series","volume":"69","author":"Sughrue ME","year":"2011","unstructured":"Sughrue ME, Saloner D, Rayz VL, Lawton MT. Giant intracranial aneurysms: evolution of management in a contemporary surgical series. 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