{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:30:17Z","timestamp":1770352217581,"version":"3.49.0"},"reference-count":54,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"22","license":[{"start":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T00:00:00Z","timestamp":1669593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,28]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Epilepsy-associated psychoses are poorly understood, and management is focused on treating epilepsy. Chronic, interictal psychosis that persists despite seizure control is typically treated with antipsychotics. Whether resection of a mesial temporal lobe lesion may improve interictal psychotic symptoms that persist despite seizure control remains unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>In a 52-year-old man with well-controlled epilepsy and persistent comorbid psychosis, brain magnetic resonance imaging (MRI) revealed an infiltrative, intraaxial, T2 fluid-attenuated inversion recovery intense mass of the left amygdala. The patient received an amygdalectomy for oncological diagnosis and surgical treatment of a presumed low-grade glioma. Pathology was ganglioglioma, World Health Organization grade I. Postoperatively, the patient reported immediate resolution of auditory hallucinations. Patient has remained seizure-free on 2 antiepileptic drugs and no antipsychotic pharmacotherapy and reported lasting improvement in his psychotic symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>This report discusses improvement of psychosis symptoms after resection of an amygdalar glioma, independent of seizure outcome. This case supports a role of the amygdala in psychopathology and suggests that low-grade gliomas of the limbic system may represent, at minimum, partially reversible etiology of psychotic symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case22362","type":"journal-article","created":{"date-parts":[[2022,11,28]],"date-time":"2022-11-28T03:05:49Z","timestamp":1669604749000},"source":"Crossref","is-referenced-by-count":4,"title":["Improved psychotic symptoms following resection of amygdalar low-grade glioma: illustrative case"],"prefix":"10.3171","volume":"4","author":[{"given":"John P.","family":"Andrews","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California; and"},{"name":"Department of Neurosurgery, San Francisco Veterans Affairs Medical Center, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Wozny","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California; and"},{"name":"Department of Neurosurgery, San Francisco Veterans Affairs Medical Center, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California; and"},{"name":"Department of Neurosurgery, San Francisco Veterans Affairs Medical Center, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris D.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California; and"},{"name":"Department of Neurosurgery, San Francisco Veterans Affairs Medical Center, San Francisco, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"2","key":"b1","series-title":"Pract Neurol","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1136\/practneurol-2017-001775","article-title":"Epilepsy and psychosis: a practical approach","volume":"18","author":"Maguire M","year":"2018","unstructured":"Maguire M, Singh J, Marson A. 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