{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:20:07Z","timestamp":1770888007499,"version":"3.50.1"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"8","license":[{"start":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T00:00:00Z","timestamp":1676851200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,20]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Spinal epidural lipomatosis (SEL) in pediatric patients with concomitant malignant brain neoplasms is rare and can present with rapid deterioration in neurological function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 4-year-old boy with SEL became paraplegic 4 months after completion of chemoradiation for his previously resected, intracranial atypical teratoid rhabdoid tumor. The patient presented with rapid deterioration in lower extremity sensory and motor function, which, given his oncological history, was concerning for disease progression. Of note, 8 months prior, the patient was started on corticosteroid therapy for respiratory dysfunction. Magnetic resonance imaging revealed significant progression of lumbosacral SEL requiring surgical decompression with subsequent neurological improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>When evaluating pediatric patients with primary or metastatic brain tumors with new or worsening myelopathy and motor or sensory deficits, it is important to consider SEL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case22556","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T08:18:05Z","timestamp":1676881085000},"source":"Crossref","is-referenced-by-count":1,"title":["Spinal epidural lipomatosis in a pediatric patient with a malignant brain tumor: illustrative case"],"prefix":"10.3171","volume":"5","author":[{"given":"Reed","family":"Berlet","sequence":"first","affiliation":[{"name":"Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, Illinois; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Department of Neurosurgery, Advocate Lutheran General Hospital, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Ruge","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Department of Neurosurgery, Advocate Lutheran General Hospital, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Childs Nerv Syst.","first-page":"757","article-title":"Management of idiopathic spinal epidural lipomatosis: a case report and review of the literature","volume":"34","author":"Papastefan ST","year":"2018","unstructured":"Papastefan ST, Bhimani AD, Denyer S,  Management of idiopathic spinal epidural lipomatosis: a case report and review of the literature. Childs Nerv Syst. 2018;34(4):757\u2013763.29273822"},{"issue":"9","key":"b2","series-title":"Clin Spine Surg.","first-page":"383","article-title":"Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases","volume":"35","author":"Alomari S","year":"2022","unstructured":"Alomari S, Lubelski D, Khalifeh JM,  Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases. Clin Spine Surg. 2022;35(9):383\u2013387.35552292"},{"issue":"2","key":"b3","series-title":"Radiology.","first-page":"485","article-title":"Epidural lipomatosis","volume":"169","author":"Quint DJ","year":"1988","unstructured":"Quint DJ, Boulos RS, Sanders WP, Mehta BA, Patel SC, Tiel RL. Epidural lipomatosis. Radiology. 1988;169(2):485\u2013490.3174998"},{"issue":"1","key":"b4","series-title":"Pediatr Rheumatol Online J.","first-page":"5","article-title":"Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature","volume":"9","author":"M\u00f6ller JC","year":"2011","unstructured":"M\u00f6ller JC, Cron RQ, Young DW,  Corticosteroid-induced spinal epidural lipomatosis in the pediatric age group: report of a new case and updated analysis of the literature. Pediatr Rheumatol Online J. 2011;9(1):5.21284882"},{"issue":"1","key":"b5","series-title":"BMC Musculoskelet Disord.","first-page":"112","article-title":"Spinal epidural lipomatosis\u2014an easily ignored secondary intraspinal disorder in spinal kyphotic deformities","volume":"18","author":"Zhang Z","year":"2017","unstructured":"Zhang Z, Liu Z, Zhu Z, Qiu Y. Spinal epidural lipomatosis\u2014an easily ignored secondary intraspinal disorder in spinal kyphotic deformities. BMC Musculoskelet Disord. 2017;18(1):112."},{"issue":"5","key":"b6","series-title":"Z Rheumatol.","first-page":"447","article-title":"[Steroid-induced spinal epidural lipomatosis in pediatric patients]","volume":"69","author":"M\u00f6ller J","year":"2010","unstructured":"M\u00f6ller J, Girschick HJ, Hahn G, Pessler F. [Steroid-induced spinal epidural lipomatosis in pediatric patients]. Z Rheumatol. 2010;69(5):447\u2013449.20213089"},{"issue":"11","key":"b7","series-title":"Spine J.","first-page":"1333","article-title":"Patient-reported outcome of surgical treatment for lumbar spinal epidural lipomatosis","volume":"16","author":"Ferlic PW","year":"2016","unstructured":"Ferlic PW, Mannion AF, Jeszenszky D,  Patient-reported outcome of surgical treatment for lumbar spinal epidural lipomatosis. Spine J. 2016;16(11):1333\u20131341.27363757"},{"issue":"3","key":"b8","series-title":"Trends Endocrinol Metab.","first-page":"86","article-title":"Do glucocorticoids cause spinal epidural lipomatosis? When endocrinology and spinal surgery meet","volume":"11","author":"Koch CA","year":"2000","unstructured":"Koch CA, Doppman JL, Patronas NJ, Nieman LK, Chrousos GP. Do glucocorticoids cause spinal epidural lipomatosis? When endocrinology and spinal surgery meet. Trends Endocrinol Metab. 2000;11(3):86\u201390.10707048"},{"issue":"4","key":"b1","series-title":"Childs Nerv Syst.","first-page":"757","article-title":"Management of idiopathic spinal epidural lipomatosis: a case report and review of the literature","volume":"34","author":"Papastefan ST","year":"2018","unstructured":"Papastefan ST, Bhimani AD, Denyer S,  Management of idiopathic spinal epidural lipomatosis: a case report and review of the literature. 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