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Magnetic resonance imaging demonstrated a ring-enhancing right parietooccipital lesion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>\n                      Biopsy and laboratory testing demonstrated an amoebic\n                      <jats:italic>Balamuthia mandrillaris<\/jats:italic>\n                      infection. Fewer than 200 cases of this infection have been recognized in the United States, and no standardized treatment regimen currently exists.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Rapid antimicrobial therapy with miltefosine, azithromycin, fluconazole, flucytosine, sulfadiazine, and albendazole was initiated. The pathophysiology, diagnosis, and management of this infection and the patient\u2019s course were reviewed. The importance of biopsy for pathologic and laboratory diagnosis and rapid treatment initiation with a multidisciplinary team was reinforced.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case2268","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T03:08:17Z","timestamp":1649646497000},"source":"Crossref","is-referenced-by-count":7,"title":["Balamuthia mandrillaris brain infection: a rare cause of a ring-enhancing central nervous system lesion. 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