{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T04:18:53Z","timestamp":1770351533432,"version":"3.49.0"},"reference-count":32,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,31]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Spinal epidural lipomatosis is a rare but well-described disease. Here the authors present an extraordinary co-occurrence of spinal epidural lipomatosis with syringomyelia that did not improve after laminoplasty but required duroplasty as a definitive treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>This is the seventh case in the literature describing a co-occurrence of spinal epidural lipomatosis and syringomyelia. The pragmatic argument for a causative relationship between 2 phenomena is syrinxes reduction after surgery for spinal epidural lipomatosis. Additionally, duroplasty for spinal epidural lipomatosis in the setting of syringomyelia has not previously been reported. Duroplasty offers much better reconstruction of the subarachnoid space as compared with extradural decompression surgeries. It is one of the treatment options for spinal epidural lipomatosis. Last, most of the patients described in the literature with secondary syringomyelia were women with diabetes mellitus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>The co-occurrence of spinal epidural lipomatosis and syringomyelia is extremely rare. Neurological deficits in such cases respond well to surgical treatment. Accordingly, each case described in the literature resulted in syringomyelia reduction or resolution after surgery. Duroplasty may be necessary in selected cases of spinal epidural lipomatosis. Close follow-up and ongoing management of patients with epidural lipomatosis is therefore important.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23249","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T09:22:52Z","timestamp":1690881772000},"source":"Crossref","is-referenced-by-count":1,"title":["Symptomatic thoracic epidural lipomatosis with syringomyelia: illustrative case"],"prefix":"10.3171","volume":"6","author":[{"given":"Lukasz","family":"Przepiorka","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"W\u00f3jtowicz","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Przemys\u0142aw","family":"Kunert","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"9","key":"b1","series-title":"Clin Spine Surg","first-page":"383","article-title":"Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases","volume":"35","author":"Alomari S","year":"2022","unstructured":"Alomari S, Lubelski D, Khalifeh JM,  Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases. Clin Spine Surg. 2022;35(9):383\u2013387.35552292"},{"issue":"1","key":"b2","series-title":"Neurosurgery","first-page":"68","article-title":"Idiopathic spinal epidural lipomatosis","volume":"41","author":"Robertson SC","year":"1997","unstructured":"Robertson SC, Traynelis VC, Follett KA, Menezes AH. Idiopathic spinal epidural lipomatosis. Neurosurgery. 1997;41(1):68\u201375.9218297"},{"issue":"8","key":"b3","series-title":"J Neurosurg Case Lessons","first-page":"1","article-title":"Spinal epidural lipomatosis in a pediatric patient with a malignant brain tumor: illustrative case","volume":"5","author":"Berlet R","year":"2023","unstructured":"Berlet R, Li D, Ruge J. Spinal epidural lipomatosis in a pediatric patient with a malignant brain tumor: illustrative case. J Neurosurg Case Lessons. 2023;5(8):1\u20135. CASE22556."},{"issue":"6","key":"b4","series-title":"Global Spine J","first-page":"658","article-title":"Spinal epidural lipomatosis: a review of pathogenesis, characteristics, clinical presentation, and management","volume":"9","author":"Kim K","year":"2019","unstructured":"Kim K, Mendelis J, Cho W. Spinal epidural lipomatosis: a review of pathogenesis, characteristics, clinical presentation, and management. Global Spine J. 2019;9(6):658\u2013665.31448201"},{"issue":"4","key":"b5","series-title":"Neurosurg Focus","first-page":"E11","article-title":"Spinal epidural lipomatosis: a review of its causes and recommendations for treatment","volume":"16","author":"Fassett DR","year":"2004","unstructured":"Fassett DR, Schmidt MH. Spinal epidural lipomatosis: a review of its causes and recommendations for treatment. Neurosurg Focus. 2004;16(4):E11.15191340"},{"issue":"4","key":"b6","series-title":"Surg Neurol","first-page":"350","article-title":"Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis","volume":"63","author":"Koyanagi I","year":"2005","unstructured":"Koyanagi I, Iwasaki Y, Hida K, Houkin K. Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis. Surg Neurol. 2005;63(4):350\u2013356.15808720"},{"issue":"3","key":"b7","series-title":"Neurosurgery","first-page":"636","article-title":"A spinal thecal sac constriction model supports the theory that induced pressure gradients in the cord cause edema and cyst formation","volume":"48","author":"Josephson A","year":"2001","unstructured":"Josephson A, Greitz D, Klason T, Olson L, Spenger C. A spinal thecal sac constriction model supports the theory that induced pressure gradients in the cord cause edema and cyst formation. Neurosurgery. 2001;48(3):636\u2013646.11270555"},{"issue":"3","key":"b8","series-title":"Neurosurgery","first-page":"762","article-title":"Spontaneous resolution of syringomyelia: report of two cases and review of the literature","volume":"53","author":"Kyoshima K","year":"2003","unstructured":"Kyoshima K, Bogdanov EI. Spontaneous resolution of syringomyelia: report of two cases and review of the literature. Neurosurgery. 2003;53(3):762\u2013769.12943593"},{"issue":"7","key":"b9","series-title":"Acta Neurochir (Wien)","first-page":"649","article-title":"The pathophysiology of syringomyelia\u2014historical overview and current concept","volume":"144","author":"Klekamp J","year":"2002","unstructured":"Klekamp J. The pathophysiology of syringomyelia\u2014historical overview and current concept. Acta Neurochir (Wien). 2002;144(7):649\u2013664.12181698"},{"key":"b10","series-title":"World Neurosurg","first-page":"4","article-title":"Multilevel hemilaminotomy windows for the surgical management of spinal epidural lipomatosis causing syringomyelia: technical note and literature review","volume":"148","author":"Mart\u00ednez Santos JL","year":"2021","unstructured":"Mart\u00ednez Santos JL, Saway B, Damon AC, Varma A. Multilevel hemilaminotomy windows for the surgical management of spinal epidural lipomatosis causing syringomyelia: technical note and literature review. World Neurosurg. 2021;148:4\u201312.33412315"},{"issue":"24","key":"b11","series-title":"J Neurosurg Case Lessons","first-page":"1","article-title":"Surgical management of thoracic myelopathy from long-segment epidural lipomatosis with skip hemilaminotomies: illustrative case","volume":"2","author":"Neal MT","year":"2021","unstructured":"Neal MT, Patra DP, Lyons MK. Surgical management of thoracic myelopathy from long-segment epidural lipomatosis with skip hemilaminotomies: illustrative case. J Neurosurg Case Lessons. 2021;2(24):1\u20134. CASE21595."},{"key":"b12","series-title":"World Neurosurg","first-page":"341","article-title":"Epidural lipomatosis and syringomyelia in adulthood: case report and literature review","volume":"129","author":"S\u00e1ez-Alegre M","year":"2019","unstructured":"S\u00e1ez-Alegre M, P\u00e9rez Lopez C, Giner Garc\u00eda J,  Epidural lipomatosis and syringomyelia in adulthood: case report and literature review. World Neurosurg. 2019;129:341\u2013344.31228704"},{"issue":"6","key":"b13","series-title":"Surg Neurol","first-page":"589","article-title":"Thoracic epidural lipomatosis with associated syrinx: case report","volume":"53","author":"Citow JS","year":"2000","unstructured":"Citow JS, Kranzler L. Thoracic epidural lipomatosis with associated syrinx: case report. Surg Neurol. 2000;53(6):589\u2013591.10940429"},{"issue":"4","key":"b14","series-title":"Turk Neurosurg","first-page":"606","article-title":"Spinal arachnoid cysts associated with syringomyelia: a review of the literature and report of a case","volume":"24","author":"Tucer B","year":"2014","unstructured":"Tucer B, Yilmaz MB, Ekici MA, Menku A, Koc K. Spinal arachnoid cysts associated with syringomyelia: a review of the literature and report of a case. Turk Neurosurg. 2014;24(4):606\u2013612.25050692"},{"issue":"5","key":"b15","series-title":"Radiol Case Rep","first-page":"528","article-title":"Thoracic epidural lipomatosis associated with syrinx: a case report","volume":"15","author":"Arora M","year":"2020","unstructured":"Arora M, Leever JD. Thoracic epidural lipomatosis associated with syrinx: a case report. Radiol Case Rep. 2020;15(5):528\u2013530.32153693"},{"key":"b16","series-title":"Int J Neurosci","first-page":"1","article-title":"Cervical syringomyelia with caudal thoracic epidural lipomatosis: case report and literature review","volume":"9","author":"Alvarado AM","year":"2022","unstructured":"Alvarado AM, Masood Z, Woodrow S. Cervical syringomyelia with caudal thoracic epidural lipomatosis: case report and literature review. Int J Neurosci. 2022;9:1\u20137."},{"issue":"9","key":"b1","series-title":"Clin Spine Surg","first-page":"383","article-title":"Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases","volume":"35","author":"Alomari S","year":"2022","unstructured":"Alomari S, Lubelski D, Khalifeh JM,  Etiologies and outcomes of spinal epidural lipomatosis: systematic review of the literature and meta-analysis of reported cases. 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CASE22556."},{"issue":"6","key":"b4","series-title":"Global Spine J","first-page":"658","article-title":"Spinal epidural lipomatosis: a review of pathogenesis, characteristics, clinical presentation, and management","volume":"9","author":"Kim K","year":"2019","unstructured":"Kim K, Mendelis J, Cho W. Spinal epidural lipomatosis: a review of pathogenesis, characteristics, clinical presentation, and management. Global Spine J. 2019;9(6):658\u2013665.31448201"},{"issue":"4","key":"b5","series-title":"Neurosurg Focus","first-page":"E11","article-title":"Spinal epidural lipomatosis: a review of its causes and recommendations for treatment","volume":"16","author":"Fassett DR","year":"2004","unstructured":"Fassett DR, Schmidt MH. Spinal epidural lipomatosis: a review of its causes and recommendations for treatment. 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Neurosurgery. 2001;48(3):636\u2013646.11270555"},{"issue":"3","key":"b8","series-title":"Neurosurgery","first-page":"762","article-title":"Spontaneous resolution of syringomyelia: report of two cases and review of the literature","volume":"53","author":"Kyoshima K","year":"2003","unstructured":"Kyoshima K, Bogdanov EI. Spontaneous resolution of syringomyelia: report of two cases and review of the literature. Neurosurgery. 2003;53(3):762\u2013769.12943593"},{"issue":"7","key":"b9","series-title":"Acta Neurochir (Wien)","first-page":"649","article-title":"The pathophysiology of syringomyelia\u2014historical overview and current concept","volume":"144","author":"Klekamp J","year":"2002","unstructured":"Klekamp J. The pathophysiology of syringomyelia\u2014historical overview and current concept. Acta Neurochir (Wien). 2002;144(7):649\u2013664.12181698"},{"key":"b10","series-title":"World Neurosurg","first-page":"4","article-title":"Multilevel hemilaminotomy windows for the surgical management of spinal epidural lipomatosis causing syringomyelia: technical note and literature review","volume":"148","author":"Mart\u00ednez Santos JL","year":"2021","unstructured":"Mart\u00ednez Santos JL, Saway B, Damon AC, Varma A. Multilevel hemilaminotomy windows for the surgical management of spinal epidural lipomatosis causing syringomyelia: technical note and literature review. World Neurosurg. 2021;148:4\u201312.33412315"},{"issue":"24","key":"b11","series-title":"J Neurosurg Case Lessons","first-page":"1","article-title":"Surgical management of thoracic myelopathy from long-segment epidural lipomatosis with skip hemilaminotomies: illustrative case","volume":"2","author":"Neal MT","year":"2021","unstructured":"Neal MT, Patra DP, Lyons MK. Surgical management of thoracic myelopathy from long-segment epidural lipomatosis with skip hemilaminotomies: illustrative case. J Neurosurg Case Lessons. 2021;2(24):1\u20134. CASE21595."},{"key":"b12","series-title":"World Neurosurg","first-page":"341","article-title":"Epidural lipomatosis and syringomyelia in adulthood: case report and literature review","volume":"129","author":"S\u00e1ez-Alegre M","year":"2019","unstructured":"S\u00e1ez-Alegre M, P\u00e9rez Lopez C, Giner Garc\u00eda J,  Epidural lipomatosis and syringomyelia in adulthood: case report and literature review. World Neurosurg. 2019;129:341\u2013344.31228704"},{"issue":"6","key":"b13","series-title":"Surg Neurol","first-page":"589","article-title":"Thoracic epidural lipomatosis with associated syrinx: case report","volume":"53","author":"Citow JS","year":"2000","unstructured":"Citow JS, Kranzler L. Thoracic epidural lipomatosis with associated syrinx: case report. 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