{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T03:47:56Z","timestamp":1779162476413,"version":"3.51.4"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"10","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,4]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Syringomyelia is a neurological disorder that is caused by abnormal cerebrospinal fluid flow or circulation. It is an incidental finding in most cases, predominantly presenting with sensory symptoms of insensitivity to pain and temperature. Spinal ossified ligamentum flavum (OLF) leading to syringomyelia is one of the rare causes. The authors report an unusual case of syringomyelia due to a thoracic OLF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 54-year-old female presented with backache, difficulty walking, spasticity in the bilateral lower limbs, tingling sensation in the bilateral lower limbs, and paraparesis for 5 years. Her radiological investigations were suggestive of an OLF causing a syrinx. She underwent laminectomy, and her syrinx resolved on subsequent follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>A syrinx due to a single-level OLF is rare, and this uncommon cause should be kept in mind while formulating treatment plans.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23340","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T21:13:05Z","timestamp":1693861985000},"source":"Crossref","is-referenced-by-count":2,"title":["Single-level ossified ligamentum flavum causing a holocord syrinx: illustrative case"],"prefix":"10.3171","volume":"6","author":[{"given":"Prashant","family":"Punia","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Chugh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarang","family":"Gotecha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apurva","family":"Lachake","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"4","key":"b1","series-title":"Neurosurg Rev","first-page":"251","article-title":"Unraveling the riddle of syringomyelia","volume":"29","author":"Greitz D","year":"2006","unstructured":"Greitz D. Unraveling the riddle of syringomyelia. Neurosurg Rev. 2006;29(4):251\u2013264."},{"issue":"5","key":"b2","series-title":"Neurosurgery","first-page":"1005","article-title":"Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients","volume":"44","author":"Milhorat TH","year":"1999","unstructured":"Milhorat TH, Chou MW, Trinidad EM,  Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients. Neurosurgery. 1999;44(5):1005\u20131017."},{"issue":"6","key":"b3","series-title":"Neurosurg Focus","first-page":"E15","article-title":"Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management","volume":"31","author":"Roy AK","year":"2011","unstructured":"Roy AK, Slimack NP, Ganju A. Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management. Neurosurg Focus. 2011;31(6):E15."},{"issue":"2","key":"b4","series-title":"J Neurosurg","first-page":"233","article-title":"Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma","volume":"86","author":"Klekamp J","year":"1997","unstructured":"Klekamp J, Batzdorf U, Samii M, Bothe HW. Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma. J Neurosurg. 1997;86(2):233\u2013240."},{"issue":"2","key":"b5","series-title":"Acta Neurochir (Wien)","first-page":"213","article-title":"Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies","volume":"152","author":"Roser F","year":"2010","unstructured":"Roser F, Ebner FH, Sixt C, Hagen JM, Tatagiba MS. Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies. Acta Neurochir (Wien). 2010;152(2):213\u2013219, discussion 219."},{"issue":"4","key":"b6","series-title":"J Clin Neurosci","first-page":"474","article-title":"Chiari malformation, cervical disc prolapse and syringomyelia--always think twice","volume":"15","author":"Ball JR","year":"2008","unstructured":"Ball JR, Little NS. Chiari malformation, cervical disc prolapse and syringomyelia--always think twice. J Clin Neurosci. 2008;15(4):474\u2013476."},{"issue":"946","key":"b7","series-title":"Br J Radiol","first-page":"e123","article-title":"A case of syringomyelia associated with cervical spondylosis","volume":"79","author":"Butteriss DJ","year":"2006","unstructured":"Butteriss DJ, Birchall D. A case of syringomyelia associated with cervical spondylosis. Br J Radiol. 2006;79(946):e123\u2013e125."},{"issue":"2","key":"b8","series-title":"Sekizui Geka","first-page":"187","article-title":"A case of syringomyelia associated with ossification of the yellow ligament: assessment of surgical outcomes using PVI and Ro. Article in Japanese","volume":"20","author":"Fukuzumi Y","year":"2006","unstructured":"Fukuzumi Y, Tani S, Isoshima A, Nagashima H, Okuda Y, Abe T. A case of syringomyelia associated with ossification of the yellow ligament: assessment of surgical outcomes using PVI and Ro. Article in Japanese. Sekizui Geka. 2006;20(2):187\u2013191."},{"issue":"4","key":"b9","series-title":"Br J Neurosurg","first-page":"413","article-title":"Cervical spondylotic myelopathy with syringomyelia","volume":"10","author":"Kaar GF","year":"1996","unstructured":"Kaar GF, N\u2019Dow JM, Bashir SH. Cervical spondylotic myelopathy with syringomyelia. Br J Neurosurg. 1996;10(4):413\u2013415."},{"issue":"11","key":"b10","series-title":"Rinsho Shinkeigaku","first-page":"1179","article-title":"Syringomyelic syndrome secondary to cervical canal stenosis and cervical spondylosis. Article in Japanese","volume":"33","author":"Kameyama T","year":"1993","unstructured":"Kameyama T, Ando T, Fukatsu H, Mizuno T, Takahashi A. Syringomyelic syndrome secondary to cervical canal stenosis and cervical spondylosis. Article in Japanese. Rinsho Shinkeigaku. 1993;33(11):1179\u20131183."},{"issue":"2","key":"b11","series-title":"Neurol Med Chir (Tokyo)","first-page":"172","article-title":"Syrinx disappearance following laminoplasty in cervical canal stenosis associated with Chiari malformation\u2014case report","volume":"50","author":"Kato N","year":"2010","unstructured":"Kato N, Tanaka T, Nagashima H,  Syrinx disappearance following laminoplasty in cervical canal stenosis associated with Chiari malformation\u2014case report. Neurol Med Chir (Tokyo). 2010; 50(2):172\u2013174."},{"issue":"2","key":"b12","series-title":"Acta Neurochir (Wien)","first-page":"175","article-title":"Syringomyelia caused by cervical spondylosis","volume":"146","author":"Kimura R","year":"2004","unstructured":"Kimura R, Park YS, Nakase H, Sakaki T. Syringomyelia caused by cervical spondylosis. Acta Neurochir (Wien). 2004;146(2):175\u2013178."},{"issue":"2","key":"b13","series-title":"J Neurosurg","first-page":"157","article-title":"Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases","volume":"99","author":"Ben Hamouda K","year":"2003","unstructured":"Ben Hamouda K, Jemel H, Haouet S, Khaldi M. Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases. J Neurosurg. 2003;99(2 suppl):157\u2013161."},{"issue":"4","key":"b14","series-title":"Surg Neurol","first-page":"350","article-title":"Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis","volume":"63","author":"Koyanagi I","year":"2005","unstructured":"Koyanagi I, Iwasaki Y, Hida K, Houkin K. Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis. Surg Neurol. 2005;63(4):350\u2013355, discussion 355-356."},{"issue":"2","key":"b15","series-title":"J Neurosurg Spine","first-page":"209","article-title":"Subarachnoid pressure-dependent change in syrinx size in a patient with syringomyelia associated with adhesive arachnoiditis. Case report","volume":"2","author":"Chang HS","year":"2005","unstructured":"Chang HS, Joko M, Matsuo N, Kim SD, Nakagawa H. Subarachnoid pressure-dependent change in syrinx size in a patient with syringomyelia associated with adhesive arachnoiditis. Case report. J Neurosurg Spine. 2005;2(2):209\u2013214."},{"issue":"3-4","key":"b16","series-title":"J Neurosurg Sci","first-page":"169","article-title":"Syringomyelia and syringomielic syndrome by cervical spondylosis. Report on three cases presenting with neurogenic osteoarthropathies","volume":"25","author":"Lucci B","year":"1981","unstructured":"Lucci B, Reverberi S, Greco G. Syringomyelia and syringomielic syndrome by cervical spondylosis. Report on three cases presenting with neurogenic osteoarthropathies. J Neurosurg Sci. 1981;25(3-4):169\u2013172."},{"issue":"2-3 Pt 1","key":"b17","series-title":"Neurochirurgie","first-page":"120","article-title":"Syringomyelobulbia associated with cervical spondylosis. Pathophysiology and therapeutic implications. Article in French","volume":"48","author":"Rebai R","year":"2002","unstructured":"Rebai R, Boudawara MZ, Ben Yahia M, Mhiri C, Ben Mansour H. Syringomyelobulbia associated with cervical spondylosis. Pathophysiology and therapeutic implications. Article in French. Neurochirurgie. 2002;48(2-3 Pt 1):120\u2013123."},{"issue":"4","key":"b1","series-title":"Neurosurg Rev","first-page":"251","article-title":"Unraveling the riddle of syringomyelia","volume":"29","author":"Greitz D","year":"2006","unstructured":"Greitz D. Unraveling the riddle of syringomyelia. Neurosurg Rev. 2006;29(4):251\u2013264."},{"issue":"5","key":"b2","series-title":"Neurosurgery","first-page":"1005","article-title":"Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients","volume":"44","author":"Milhorat TH","year":"1999","unstructured":"Milhorat TH, Chou MW, Trinidad EM,  Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients. Neurosurgery. 1999;44(5):1005\u20131017."},{"issue":"6","key":"b3","series-title":"Neurosurg Focus","first-page":"E15","article-title":"Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management","volume":"31","author":"Roy AK","year":"2011","unstructured":"Roy AK, Slimack NP, Ganju A. Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management. Neurosurg Focus. 2011;31(6):E15."},{"issue":"2","key":"b4","series-title":"J Neurosurg","first-page":"233","article-title":"Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma","volume":"86","author":"Klekamp J","year":"1997","unstructured":"Klekamp J, Batzdorf U, Samii M, Bothe HW. Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma. J Neurosurg. 1997;86(2):233\u2013240."},{"issue":"2","key":"b5","series-title":"Acta Neurochir (Wien)","first-page":"213","article-title":"Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies","volume":"152","author":"Roser F","year":"2010","unstructured":"Roser F, Ebner FH, Sixt C, Hagen JM, Tatagiba MS. Defining the line between hydromyelia and syringomyelia. A differentiation is possible based on electrophysiological and magnetic resonance imaging studies. Acta Neurochir (Wien). 2010;152(2):213\u2013219, discussion 219."},{"issue":"4","key":"b6","series-title":"J Clin Neurosci","first-page":"474","article-title":"Chiari malformation, cervical disc prolapse and syringomyelia--always think twice","volume":"15","author":"Ball JR","year":"2008","unstructured":"Ball JR, Little NS. Chiari malformation, cervical disc prolapse and syringomyelia--always think twice. J Clin Neurosci. 2008;15(4):474\u2013476."},{"issue":"946","key":"b7","series-title":"Br J Radiol","first-page":"e123","article-title":"A case of syringomyelia associated with cervical spondylosis","volume":"79","author":"Butteriss DJ","year":"2006","unstructured":"Butteriss DJ, Birchall D. A case of syringomyelia associated with cervical spondylosis. Br J Radiol. 2006;79(946):e123\u2013e125."},{"issue":"2","key":"b8","series-title":"Sekizui Geka","first-page":"187","article-title":"A case of syringomyelia associated with ossification of the yellow ligament: assessment of surgical outcomes using PVI and Ro. Article in Japanese","volume":"20","author":"Fukuzumi Y","year":"2006","unstructured":"Fukuzumi Y, Tani S, Isoshima A, Nagashima H, Okuda Y, Abe T. A case of syringomyelia associated with ossification of the yellow ligament: assessment of surgical outcomes using PVI and Ro. Article in Japanese. Sekizui Geka. 2006;20(2):187\u2013191."},{"issue":"4","key":"b9","series-title":"Br J Neurosurg","first-page":"413","article-title":"Cervical spondylotic myelopathy with syringomyelia","volume":"10","author":"Kaar GF","year":"1996","unstructured":"Kaar GF, N\u2019Dow JM, Bashir SH. Cervical spondylotic myelopathy with syringomyelia. Br J Neurosurg. 1996;10(4):413\u2013415."},{"issue":"11","key":"b10","series-title":"Rinsho Shinkeigaku","first-page":"1179","article-title":"Syringomyelic syndrome secondary to cervical canal stenosis and cervical spondylosis. Article in Japanese","volume":"33","author":"Kameyama T","year":"1993","unstructured":"Kameyama T, Ando T, Fukatsu H, Mizuno T, Takahashi A. Syringomyelic syndrome secondary to cervical canal stenosis and cervical spondylosis. Article in Japanese. Rinsho Shinkeigaku. 1993;33(11):1179\u20131183."},{"issue":"2","key":"b11","series-title":"Neurol Med Chir (Tokyo)","first-page":"172","article-title":"Syrinx disappearance following laminoplasty in cervical canal stenosis associated with Chiari malformation\u2014case report","volume":"50","author":"Kato N","year":"2010","unstructured":"Kato N, Tanaka T, Nagashima H,  Syrinx disappearance following laminoplasty in cervical canal stenosis associated with Chiari malformation\u2014case report. Neurol Med Chir (Tokyo). 2010; 50(2):172\u2013174."},{"issue":"2","key":"b12","series-title":"Acta Neurochir (Wien)","first-page":"175","article-title":"Syringomyelia caused by cervical spondylosis","volume":"146","author":"Kimura R","year":"2004","unstructured":"Kimura R, Park YS, Nakase H, Sakaki T. Syringomyelia caused by cervical spondylosis. Acta Neurochir (Wien). 2004;146(2):175\u2013178."},{"issue":"2","key":"b13","series-title":"J Neurosurg","first-page":"157","article-title":"Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases","volume":"99","author":"Ben Hamouda K","year":"2003","unstructured":"Ben Hamouda K, Jemel H, Haouet S, Khaldi M. Thoracic myelopathy caused by ossification of the ligamentum flavum: a report of 18 cases. J Neurosurg. 2003;99(2 suppl):157\u2013161."},{"issue":"4","key":"b14","series-title":"Surg Neurol","first-page":"350","article-title":"Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis","volume":"63","author":"Koyanagi I","year":"2005","unstructured":"Koyanagi I, Iwasaki Y, Hida K, Houkin K. Clinical features and pathomechanisms of syringomyelia associated with spinal arachnoiditis. Surg Neurol. 2005;63(4):350\u2013355, discussion 355-356."},{"issue":"2","key":"b15","series-title":"J Neurosurg Spine","first-page":"209","article-title":"Subarachnoid pressure-dependent change in syrinx size in a patient with syringomyelia associated with adhesive arachnoiditis. Case report","volume":"2","author":"Chang HS","year":"2005","unstructured":"Chang HS, Joko M, Matsuo N, Kim SD, Nakagawa H. Subarachnoid pressure-dependent change in syrinx size in a patient with syringomyelia associated with adhesive arachnoiditis. Case report. J Neurosurg Spine. 2005;2(2):209\u2013214."},{"issue":"3-4","key":"b16","series-title":"J Neurosurg Sci","first-page":"169","article-title":"Syringomyelia and syringomielic syndrome by cervical spondylosis. Report on three cases presenting with neurogenic osteoarthropathies","volume":"25","author":"Lucci B","year":"1981","unstructured":"Lucci B, Reverberi S, Greco G. Syringomyelia and syringomielic syndrome by cervical spondylosis. Report on three cases presenting with neurogenic osteoarthropathies. J Neurosurg Sci. 1981;25(3-4):169\u2013172."},{"issue":"2-3 Pt 1","key":"b17","series-title":"Neurochirurgie","first-page":"120","article-title":"Syringomyelobulbia associated with cervical spondylosis. Pathophysiology and therapeutic implications. Article in French","volume":"48","author":"Rebai R","year":"2002","unstructured":"Rebai R, Boudawara MZ, Ben Yahia M, Mhiri C, Ben Mansour H. Syringomyelobulbia associated with cervical spondylosis. Pathophysiology and therapeutic implications. 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