{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:05:08Z","timestamp":1771038308273,"version":"3.50.1"},"reference-count":52,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Ependymoma is the third most common pediatric brain tumor that can present with headaches, cranial nerve deficits, nausea, vomiting, and ataxia. Current treatment is maximal safe resection followed by radiation therapy. More recently, laser interstitial thermal therapy (LITT) has become an alternative to traditional resection. In this report, the authors describe the utilization of a single-use, patient-specific stereotactic platform for the treatment of supratentorial ependymoma with LITT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 2-year-old female had a complex history of supratentorial ependymoma after multiple craniotomies for repeated tumor progression and ventriculoperitoneal shunt placement. Imaging demonstrated an enlarging, complex, enhancing mass in the right occipital region. LITT was decided on for treatment. Given the thinness of the patient\u2019s skull, which precluded traditional means of stereotaxy, the authors elected to use a personalized stereotactic platform. Immediate postoperative imaging captured complete laser ablation of the tumor, with long-term imaging demonstrating a decreased tumor size.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Individualized stereotactic platforms are increasingly used in adult populations, but pediatric use continues to be infrequent. In this report, the authors present the youngest reported case using a personalized stereotactic platform and show the effectiveness of this system for performing LITT in the youngest of populations with very thin skulls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23513","type":"journal-article","created":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T18:52:58Z","timestamp":1704135178000},"source":"Crossref","is-referenced-by-count":3,"title":["Overcoming the challenge of a thin skull in a 2-year-old patient undergoing laser interstitial thermal therapy using an individualized stereotactic platform: illustrative case"],"prefix":"10.3171","volume":"7","author":[{"given":"Spencer","family":"Lau","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Menousek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Pistone","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnett","family":"Klugh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska; and"},{"name":"Children\u2019s Nebraska, Omaha, Nebraska"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afshin","family":"Salehi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Nebraska Medical Center, Omaha, Nebraska; and"},{"name":"Children\u2019s Nebraska, Omaha, Nebraska"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neuro Oncol","first-page":"v1","article-title":"CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2012-2016","volume":"21","author":"Ostrom QT","year":"2019","unstructured":"Ostrom QT, Cioffi G, Gittleman H,  CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2012-2016. Neuro Oncol. 2019;21(suppl 5):v1-v100."},{"issue":"12","key":"b2","series-title":"J Child Neurol","first-page":"1354","article-title":"Pediatric ependymoma","volume":"31","author":"Vitanza NA","year":"2016","unstructured":"Vitanza NA, Partap S. Pediatric ependymoma. J Child Neurol. 2016;31(12):1354\u20131366."},{"issue":"6","key":"b3","series-title":"Mol Cancer Res","first-page":"765","article-title":"Pediatric ependymoma: biological perspectives","volume":"7","author":"Kilday JP","year":"2009","unstructured":"Kilday JP, Rahman R, Dyer S,  Pediatric ependymoma: biological perspectives. Mol Cancer Res. 2009;7(6):765\u2013786."},{"issue":"3","key":"b4","series-title":"Neurol Clin","first-page":"829","article-title":"Pediatric Neuro-Oncology","volume":"39","author":"Malbari F","year":"2021","unstructured":"Malbari F. Pediatric Neuro-Oncology. Neurol Clin. 2021;39(3):829\u2013845."},{"issue":"1","key":"b5","series-title":"Lancet Oncol","first-page":"35","article-title":"Childhood cancer survival in Europe 1999-2007: results of EUROCARE-5--a population-based study","volume":"15","author":"Gatta G","year":"2014","unstructured":"Gatta G, Botta L, Rossi S,  Childhood cancer survival in Europe 1999-2007: results of EUROCARE-5--a population-based study. Lancet Oncol. 2014;15(1):35\u201347."},{"issue":"3","key":"b6","series-title":"Lancet Oncol","first-page":"258","article-title":"Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study","volume":"10","author":"Merchant TE","year":"2009","unstructured":"Merchant TE, Li C, Xiong X, Kun LE, Boop FA, Sanford RA. Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. 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