{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T20:07:39Z","timestamp":1770494859193,"version":"3.49.0"},"reference-count":72,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","license":[{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,22]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Aneurysmal bone cysts (ABCs) are rare, highly vascular osteolytic bone lesions that predominantly affect pediatric populations. This report evaluates the clinicopathological data of pediatric patients with spinal ABCs. The medical records for all patients at Children\u2019s Hospital Los Angeles with biopsy-proven ABCs of the spine between 1998 and 2018 were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>Seventeen patients, 6 males and 11 females, were identified. The mean age at surgery was 10.4 years (range, 3.5\u201320 years). The most common presenting complaint was pain at the lesion site 16\/17 (94%), followed by lower-extremity weakness 8\/17 (47%). Resection and intralesional curettage were performed in all patients. Three (18%) of 17 patients underwent selective arterial embolization prior to resection. Spinal stability was compromised in 15 of 17 patients (88%), requiring instrumented fusion. Five (29%) of the 17 patients received additional therapy including radiation, calcitonin-methylprednisolone, or phenol. Four (23.5%) of 17 patients experienced a recurrence, and the mean time to recurrence was 15 months. The postoperative follow-up ranged from 6 to 108 months (median, 28 months). Reoperation occurred after an average of 35 months. At the recent follow-up, patients were free of disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Gross-total resection by intralesional curettage with case-dependent instrumented spinal fusion for instability remains an effective strategy for managing pediatric spinal ABCs. Long-term follow-up is necessary to detect tumor recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23637","type":"journal-article","created":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T19:50:42Z","timestamp":1705953042000},"source":"Crossref","is-referenced-by-count":2,"title":["Surgical management of pediatric spinal aneurysmal bone cysts: patient series"],"prefix":"10.3171","volume":"7","author":[{"given":"Benjamin E","family":"Flyer","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"},{"name":"Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik B","family":"Vanstrum","sequence":"additional","affiliation":[{"name":"Department of UCLA Head & Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Chapman","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph H","family":"Ha","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob K","family":"Al-Husseini","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason K","family":"Chu","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Gordon","family":"McComb","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan R","family":"Durham","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D","family":"Krieger","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"},{"name":"Department of Surgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine of USC, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A","family":"Chiarelli","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Children\u2019s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"Bull Hosp Jt Dis.","first-page":"3","article-title":"Aneurysmal bone cyst","volume":"11","author":"Jaffe HL","year":"1950","unstructured":"Jaffe HL Aneurysmal bone cyst. Bull Hosp Jt Dis. 1950;11(1):3\u201313."},{"issue":"4","key":"b2","series-title":"J Bone Joint Surg Am.","first-page":"873","article-title":"Aneurysmal bone cyst: observations on fifty cases","volume":"39-A","author":"Lichtenstein L","year":"1957","unstructured":"Lichtenstein L Aneurysmal bone cyst: observations on fifty cases. J Bone Joint Surg Am. 1957;39-A(4):873\u2013882."},{"issue":"5","key":"b3","series-title":"Cancer.","first-page":"1208","article-title":"The World Health Organization\u2019s histologic classification of bone tumors. A commentary on the second edition","volume":"75","author":"Schajowicz F","year":"1995","unstructured":"Schajowicz F, Sissons HA, Sobin LH The World Health Organization\u2019s histologic classification of bone tumors. A commentary on the second edition. 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