{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T09:18:47Z","timestamp":1770887927050,"version":"3.50.1"},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"9","license":[{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,26]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Diffuse spinal dural calcification is a rare disorder associated with hyperparathyroidism, including the secondary forms associated with renal failure, osteodystrophy, and chronic hypocalcemia. Here, the authors report a rare case of diffuse dural calcification causing spinal cord compression with myelopathy, requiring decompressive surgery with duraplasty to achieve adequate decompression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 46-year-old male with a history of renal failure on dialysis presented with 2 months of progressive neuropathic pain, lower-extremity weakness, and nonsustained clonus. Spine imaging showed severe renal osteodystrophy with multilevel compression fractures and diffuse dural calcifications with areas of invagination causing severe spinal cord compression. Decompressive surgery was recommended. In surgery, a thickened and calcified dura was encountered with areas of buckling causing spinal cord compression. The invaginated area of the dura was resected and reconstructed with patch duraplasty. The patient\u2019s neurological status remained unchanged postoperatively, and at the 6-month follow-up, the patient reported significant improvement in pain and muscle spasms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Diffuse dural calcifications are a rare complication of prolonged dialysis and secondary hyperparathyroidism. When there is resultant spinal cord compression, this condition requires an intradural approach that addresses the thickened, calcified dura directly to obtain adequate spinal cord decompression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23641","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T18:58:44Z","timestamp":1708973924000},"source":"Crossref","is-referenced-by-count":3,"title":["Compressive myelopathy from diffuse spinal dural calcifications in a patient with end-stage renal disease: illustrative case"],"prefix":"10.3171","volume":"7","author":[{"given":"Alexis","family":"Malecki","sequence":"first","affiliation":[{"name":"Wayne State University School of Medicine, Detroit, Michigan; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Pawloski","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Henry Ford Health, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Anzalone","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Henry Ford Health, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Shaftel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Henry Ford Health, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan Ali","family":"Fadel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Henry Ford Health, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Henry Ford Health, Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"5","key":"b1","series-title":"Semin Dial","first-page":"477","article-title":"Extraosseous calcification in end-stage renal disease: from visceral organs to vasculature","volume":"27","author":"Molenaar FM","year":"2014","unstructured":"Molenaar FM, van Reekum FE, Rookmaaker MB, Abrahams AC, van Jaarsveld BC Extraosseous calcification in end-stage renal disease: from visceral organs to vasculature. Semin Dial. 2014;27(5):477\u2013487."},{"issue":"6","key":"b2","series-title":"Semin Nephrol","first-page":"488","article-title":"Renal osteodystrophy in chronic renal failure","volume":"22","author":"Ho LT","year":"2002","unstructured":"Ho LT, Sprague SM Renal osteodystrophy in chronic renal failure. Semin Nephrol. 2002;22(6):488\u2013493."},{"issue":"3","key":"b3","series-title":"Kidney Res Clin Pract","first-page":"132","article-title":"Lessons from 30 years\u2019 data of Korean end-stage renal disease registry, 1985\u20132015","volume":"34","author":"Jin DC","year":"2015","unstructured":"Jin DC, Yun SR, Lee SW,  Lessons from 30 years\u2019 data of Korean end-stage renal disease registry, 1985\u20132015. Kidney Res Clin Pract. 2015;34(3):132\u2013139."},{"issue":"5","key":"b4","series-title":"Nephrol Dial Transplant","first-page":"1715","article-title":"FGF23 and PTH\u2014double agents at the heart of CKD","volume":"27","author":"Silver J","year":"2012","unstructured":"Silver J, Rodriguez M, Slatopolsky E FGF23 and PTH\u2014double agents at the heart of CKD. Nephrol Dial Transplant. 2012;27(5):1715\u20131720."},{"issue":"2","key":"b5","series-title":"Cleve Clin J Med","first-page":"81","article-title":"Extraosseous calcification in kidney disease","volume":"89","author":"Bartolomeo K","year":"2022","unstructured":"Bartolomeo K, Tan XY, Fatica R Extraosseous calcification in kidney disease. Cleve Clin J Med. 2022;89(2):81\u201390."},{"issue":"1","key":"b6","series-title":"Nephron","first-page":"31","article-title":"Cerebral imaging changes in patients with chronic renal failure treated conservatively or in hemodialysis","volume":"89","author":"Savazzi GM","year":"2001","unstructured":"Savazzi GM, Cusmano F, Musini S Cerebral imaging changes in patients with chronic renal failure treated conservatively or in hemodialysis. Nephron. 2001;89(1):31\u201336."},{"issue":"3","key":"b7","series-title":"Clin Radiol","first-page":"349","article-title":"Dural calcification: a complication of prolonged periodic haemodialysis","volume":"25","author":"Ritchie WG","year":"1974","unstructured":"Ritchie WG, Davison AM Dural calcification: a complication of prolonged periodic haemodialysis. Clin Radiol. 1974;25(3):349\u2013353."},{"issue":"2","key":"b8","series-title":"JBR-BTR","first-page":"78","article-title":"Left atrial, pulmonary vein and dural calcification in a patient with arrhythmia and chronic renal failure","volume":"88","author":"Koroglu M","year":"2005","unstructured":"Koroglu M, Chen PS, Oto A, Koroglu BK Left atrial, pulmonary vein and dural calcification in a patient with arrhythmia and chronic renal failure. JBR-BTR. 2005;88(2):78\u201379."},{"issue":"2","key":"b9","series-title":"Neuroradiology","first-page":"107","article-title":"Total dural calcification with secondary hyperparathyoidism: a rare entity","volume":"15","author":"Besigye E","year":"1978","unstructured":"Besigye E, Johansen JG, Osnes S Total dural calcification with secondary hyperparathyoidism: a rare entity. Neuroradiology. 1978;15(2):107\u2013109."},{"key":"b10","series-title":"Eur Radiol","first-page":"S11","article-title":"Tentorial and dural calcification with tertiary hyperparathyroidism: a rare entity in chronic renal failure","volume":"12","author":"Dorenbeck U","year":"2002","unstructured":"Dorenbeck U, Leing\u00e4rtner T, Bretschneider T, Kr\u00e4mer BK, Feuerbach S Tentorial and dural calcification with tertiary hyperparathyroidism: a rare entity in chronic renal failure. Eur Radiol. 2002;12(suppl 3):S11\u2013S13."},{"issue":"6","key":"b11","series-title":"Rheumatology (Oxford)","first-page":"868","article-title":"Recognizing the clinical triad and dural calcification in adult hypophosphatasia","volume":"56","author":"Chew LC","year":"2017","unstructured":"Chew LC, Tong C, Bryant C, Joshua F Recognizing the clinical triad and dural calcification in adult hypophosphatasia. Rheumatology (Oxford). 2017;56(6):868."},{"issue":"2","key":"b12","series-title":"Br J Neurosurg","first-page":"222","article-title":"Cervical dural calcification and cervical myelopathy in X-linked hypophosphataemic rickets: a case report and review of the literature","volume":"33","author":"Najefi AA","year":"2019","unstructured":"Najefi AA, Beder DB, Sabah SA, Rezajooi K Cervical dural calcification and cervical myelopathy in X-linked hypophosphataemic rickets: a case report and review of the literature. Br J Neurosurg. 2019;33(2):222\u2013223."},{"issue":"5","key":"b13","series-title":"Can J Neurol Sci","first-page":"568","article-title":"Compressive cervical myelopathy in X-linked hypophosphataemic rickets","volume":"45","author":"Fearon C","year":"2018","unstructured":"Fearon C, Abbas A, Ryan SA, Fitzgerald SJ, Looby S Compressive cervical myelopathy in X-linked hypophosphataemic rickets. Can J Neurol Sci. 2018;45(5):568\u2013570."},{"issue":"1","key":"b14","series-title":"Insights Imaging","first-page":"11","article-title":"Dural masses: meningiomas and their mimics","volume":"10","author":"Lyndon D","year":"2019","unstructured":"Lyndon D, Lansley JA, Evanson J, Krishnan AS Dural masses: meningiomas and their mimics. Insights Imaging. 2019;10(1):11."},{"issue":"5","key":"b1","series-title":"Semin Dial","first-page":"477","article-title":"Extraosseous calcification in end-stage renal disease: from visceral organs to vasculature","volume":"27","author":"Molenaar FM","year":"2014","unstructured":"Molenaar FM, van Reekum FE, Rookmaaker MB, Abrahams AC, van Jaarsveld BC Extraosseous calcification in end-stage renal disease: from visceral organs to vasculature. Semin Dial. 2014;27(5):477\u2013487."},{"issue":"6","key":"b2","series-title":"Semin Nephrol","first-page":"488","article-title":"Renal osteodystrophy in chronic renal failure","volume":"22","author":"Ho LT","year":"2002","unstructured":"Ho LT, Sprague SM Renal osteodystrophy in chronic renal failure. Semin Nephrol. 2002;22(6):488\u2013493."},{"issue":"3","key":"b3","series-title":"Kidney Res Clin Pract","first-page":"132","article-title":"Lessons from 30 years\u2019 data of Korean end-stage renal disease registry, 1985\u20132015","volume":"34","author":"Jin DC","year":"2015","unstructured":"Jin DC, Yun SR, Lee SW,  Lessons from 30 years\u2019 data of Korean end-stage renal disease registry, 1985\u20132015. Kidney Res Clin Pract. 2015;34(3):132\u2013139."},{"issue":"5","key":"b4","series-title":"Nephrol Dial Transplant","first-page":"1715","article-title":"FGF23 and PTH\u2014double agents at the heart of CKD","volume":"27","author":"Silver J","year":"2012","unstructured":"Silver J, Rodriguez M, Slatopolsky E FGF23 and PTH\u2014double agents at the heart of CKD. Nephrol Dial Transplant. 2012;27(5):1715\u20131720."},{"issue":"2","key":"b5","series-title":"Cleve Clin J Med","first-page":"81","article-title":"Extraosseous calcification in kidney disease","volume":"89","author":"Bartolomeo K","year":"2022","unstructured":"Bartolomeo K, Tan XY, Fatica R Extraosseous calcification in kidney disease. Cleve Clin J Med. 2022;89(2):81\u201390."},{"issue":"1","key":"b6","series-title":"Nephron","first-page":"31","article-title":"Cerebral imaging changes in patients with chronic renal failure treated conservatively or in hemodialysis","volume":"89","author":"Savazzi GM","year":"2001","unstructured":"Savazzi GM, Cusmano F, Musini S Cerebral imaging changes in patients with chronic renal failure treated conservatively or in hemodialysis. Nephron. 2001;89(1):31\u201336."},{"issue":"3","key":"b7","series-title":"Clin Radiol","first-page":"349","article-title":"Dural calcification: a complication of prolonged periodic haemodialysis","volume":"25","author":"Ritchie WG","year":"1974","unstructured":"Ritchie WG, Davison AM Dural calcification: a complication of prolonged periodic haemodialysis. Clin Radiol. 1974;25(3):349\u2013353."},{"issue":"2","key":"b8","series-title":"JBR-BTR","first-page":"78","article-title":"Left atrial, pulmonary vein and dural calcification in a patient with arrhythmia and chronic renal failure","volume":"88","author":"Koroglu M","year":"2005","unstructured":"Koroglu M, Chen PS, Oto A, Koroglu BK Left atrial, pulmonary vein and dural calcification in a patient with arrhythmia and chronic renal failure. JBR-BTR. 2005;88(2):78\u201379."},{"issue":"2","key":"b9","series-title":"Neuroradiology","first-page":"107","article-title":"Total dural calcification with secondary hyperparathyoidism: a rare entity","volume":"15","author":"Besigye E","year":"1978","unstructured":"Besigye E, Johansen JG, Osnes S Total dural calcification with secondary hyperparathyoidism: a rare entity. Neuroradiology. 1978;15(2):107\u2013109."},{"key":"b10","series-title":"Eur Radiol","first-page":"S11","article-title":"Tentorial and dural calcification with tertiary hyperparathyroidism: a rare entity in chronic renal failure","volume":"12","author":"Dorenbeck U","year":"2002","unstructured":"Dorenbeck U, Leing\u00e4rtner T, Bretschneider T, Kr\u00e4mer BK, Feuerbach S Tentorial and dural calcification with tertiary hyperparathyroidism: a rare entity in chronic renal failure. Eur Radiol. 2002;12(suppl 3):S11\u2013S13."},{"issue":"6","key":"b11","series-title":"Rheumatology (Oxford)","first-page":"868","article-title":"Recognizing the clinical triad and dural calcification in adult hypophosphatasia","volume":"56","author":"Chew LC","year":"2017","unstructured":"Chew LC, Tong C, Bryant C, Joshua F Recognizing the clinical triad and dural calcification in adult hypophosphatasia. Rheumatology (Oxford). 2017;56(6):868."},{"issue":"2","key":"b12","series-title":"Br J Neurosurg","first-page":"222","article-title":"Cervical dural calcification and cervical myelopathy in X-linked hypophosphataemic rickets: a case report and review of the literature","volume":"33","author":"Najefi AA","year":"2019","unstructured":"Najefi AA, Beder DB, Sabah SA, Rezajooi K Cervical dural calcification and cervical myelopathy in X-linked hypophosphataemic rickets: a case report and review of the literature. Br J Neurosurg. 2019;33(2):222\u2013223."},{"issue":"5","key":"b13","series-title":"Can J Neurol Sci","first-page":"568","article-title":"Compressive cervical myelopathy in X-linked hypophosphataemic rickets","volume":"45","author":"Fearon C","year":"2018","unstructured":"Fearon C, Abbas A, Ryan SA, Fitzgerald SJ, Looby S Compressive cervical myelopathy in X-linked hypophosphataemic rickets. Can J Neurol Sci. 2018;45(5):568\u2013570."},{"issue":"1","key":"b14","series-title":"Insights Imaging","first-page":"11","article-title":"Dural masses: meningiomas and their mimics","volume":"10","author":"Lyndon D","year":"2019","unstructured":"Lyndon D, Lansley JA, Evanson J, Krishnan AS Dural masses: meningiomas and their mimics. Insights Imaging. 2019;10(1):11."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/7\/9\/article-CASE23641.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/7\/9\/article-CASE23641.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/7\/9\/article-CASE23641.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T14:24:54Z","timestamp":1770301494000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/7\/9\/article-CASE23641.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":28,"journal-issue":{"issue":"9"},"URL":"https:\/\/doi.org\/10.3171\/case23641","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,26]]}}}