{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T19:56:16Z","timestamp":1785527776050,"version":"3.56.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","license":[{"start":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T00:00:00Z","timestamp":1720396800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2024,7,8]]},"abstract":"\n BACKGROUND<\/jats:title>\n Choroid plexus carcinomas (CPCs) are rare malignant brain tumors primarily affecting children younger than 2 years old. These tumors originate from the choroid plexus epithelium and are a subtype of choroid plexus tumors, which account for 1%\u20134% of pediatric brain tumors. Although CPCs often show a notably high recurrence rate after surgery, the standard treatment approach remains gross-total resection (GTR) of the tumor, given the lack of clinical data supporting the effectiveness of adjunct treatment options such as radiotherapy or chemotherapy.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n A 16-year-old female with a history of a recurrent cranial CPC resistant to surgery and radiotherapy was treated with CyberKnife stereotactic radiosurgery (SRS), following resection. The procedures successfully maintained local disease control for 41 months; however, there was a subsequent recurrence, ultimately leading to the death of the patient.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n CPC treatment remains challenging. SRS can be used as a viable adjunct to surgery, which remains the gold standard, although it can also be considered for nonsurgical candidates or when GTR cannot be achieved. Nevertheless, it is crucial to conduct additional research to explore diverse approaches for radiosurgery, including its role as the primary treatment modality versus its combination with surgery, radiotherapy, or chemotherapy.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE23748<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case23748","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T02:49:49Z","timestamp":1720406989000},"source":"Crossref","is-referenced-by-count":2,"title":["Recurrent choroid plexus carcinoma treated with CyberKnife radiosurgery: illustrative case"],"prefix":"10.3171","volume":"8","author":[{"given":"Lorenzo","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit R. L","family":"Persad","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke S","family":"Hori","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armine","family":"Tayag","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louisa","family":"Ustrzynski","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara C","family":"Emrich","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"8","key":"bib1","series-title":"Neuro Oncol","first-page":"1231","article-title":"The 2021 WHO Classification of tumors of the central nervous system: a summary","volume":"23","author":"Louis","year":"2021","unstructured":"Louis DNPerry AWesseling P, et al. The 2021 WHO Classification of tumors of the central nervous system: a summary. Neuro Oncol. 2021;23(8):1231-1251."},{"key":"bib2","series-title":"NMC Case Rep J","first-page":"301","article-title":"Delayed recurrence of choroid plexus carcinoma in the sacral spinal cord 17 years after its initial presentation","volume":"9","author":"Nagai","year":"2022","unstructured":"Nagai AKanamori MShimoda Y, et al. Delayed recurrence of choroid plexus carcinoma in the sacral spinal cord 17 years after its initial presentation. NMC Case Rep J. 2022;9:301-306."},{"issue":"5","key":"bib3","series-title":"Pediatr Blood Cancer","first-page":"784","article-title":"Choroid plexus carcinoma in children: the head start experience","volume":"62","author":"Zaky","year":"2015","unstructured":"Zaky WDhall GKhatua S, et al. Choroid plexus carcinoma in children: the head start experience. Pediatr Blood Cancer. 2015;62(5):784-789."},{"key":"bib4","series-title":"J Clin Neurosci","first-page":"148","article-title":"Disseminated choroid plexus papillomas in adults: a case series and review of the literature","volume":"32","author":"Abdulkader","year":"2016","unstructured":"Abdulkader MMMansour NHVan Gompel JJ, et al. Disseminated choroid plexus papillomas in adults: a case series and review of the literature. J Clin Neurosci. 2016;32:148-154."},{"issue":"5","key":"bib5","series-title":"Int J Radiat Oncol Biol Phys","first-page":"1199","article-title":"Effect of surgery","volume":"99","author":"Mallick","year":"2017","unstructured":"Mallick SBenson RMelgandi WRath GK. Effect of surgery, adjuvant therapy, and other prognostic factors on choroid plexus carcinoma: systematic review and individual patient data analysis. 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Choroid plexus tumours. Br J Cancer. 2002;87(10):1086-1091."},{"issue":"9170","key":"bib9","series-title":"Lancet","first-page":"2126","article-title":"Radiation therapy and survival in choroid plexus carcinoma","volume":"353","author":"Wolff","year":"1999","unstructured":"Wolff JESajedi MCoppes MJAnderson RAEgeler RM. Radiation therapy and survival in choroid plexus carcinoma. Lancet. 1999;353(9170):2126."},{"issue":"4","key":"bib10","series-title":"Neurosurgery","first-page":"791","article-title":"Stereotactic radiosurgery for choroid plexus tumors: a report of the international radiosurgery Research Foundation","volume":"88","author":"Faramand","year":"2021","unstructured":"Faramand AKano HNiranjan A, et al. Stereotactic radiosurgery for choroid plexus tumors: a report of the international radiosurgery Research Foundation. 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J Neurooncol. 2017;132(3):427-432."},{"issue":"12","key":"bib13","series-title":"Neurol Med Chir (Tokyo)","first-page":"891","article-title":"Choroid plexus tumors: experience of 10 cases with special references to adult cases","volume":"55","author":"Bohara","year":"2015","unstructured":"Bohara MHirabaru MFujio S, et al. Choroid plexus tumors: experience of 10 cases with special references to adult cases. Neurol Med Chir (Tokyo). 2015;55(12):891-900."},{"issue":"suppl","key":"bib14","series-title":"J Neurol Surg A Cent Eur Neurosurg","first-page":"e149","article-title":"Recurrent adult choroid plexus carcinoma treated with high-dose chemotherapy and syngeneic stem cell (bone marrow) transplant","volume":"74","author":"Samuel","year":"2013","unstructured":"Samuel TAParikh JSharma S, et al. Recurrent adult choroid plexus carcinoma treated with high-dose chemotherapy and syngeneic stem cell (bone marrow) transplant. J Neurol Surg A Cent Eur Neurosurg. 2013;74(suppl 1):e149-e154."},{"issue":"2","key":"bib15","series-title":"Tumor Discov","first-page":"1057","article-title":"Choroid plexus tumors: a spectrum from benign to malignant","volume":"2","author":"Mohamed","year":"2023","unstructured":"Mohamed AACaussat TKelly SJohansen PMLucke-Wold B. Choroid plexus tumors: a spectrum from benign to malignant. Tumor Discov. 2023;2(2):1057."},{"issue":"12","key":"bib16","series-title":"J Clin Oncol","first-page":"1995","article-title":"TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors","volume":"28","author":"Tabori","year":"2010","unstructured":"Tabori UShlien ABaskin B, et al. TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. 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