{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T16:11:50Z","timestamp":1770394310343,"version":"3.49.0"},"reference-count":40,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"10","license":[{"start":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T00:00:00Z","timestamp":1709510400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,4]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Chondrosarcoma is an uncommon spinal tumor that can present as an extraskeletal mass. Rarely, these tumors present as dumbbell tumors through the neural foramina, mimicking schwannomas or neurofibromas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 46-year-old female presented with 2 years of worsening right-arm radiculopathy. Magnetic resonance imaging of the thoracic spine revealed a peripherally enhancing extramedullary mass through the right T1 foramen and compressing the spinal cord. Computed tomography showed the mass to be partially calcified. She underwent C7\u2013T2 laminectomy and C6\u2013T3 posterior instrumented fusion with gross-total resection of an extradural mass. Pathology revealed a grade I chondrosarcoma. Her symptoms improved postoperatively, with some residual right-arm radicular pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Intraspinal extradural dumbbell conventional chondrosarcoma is rare, with only 9 cases, including ours, reported. Patient ages range from 16 to 72 years old, and male sex is more common in these cases. The most common location is the thoracic spine, and our case is the only reported one in the cervicothoracic junction. These tumors often mimic schwannomas on imaging, but chondrosarcoma should remain in the differential diagnosis, because management of these tumors differs. Chondrosarcoma may benefit from more aggressive resection, including en bloc resection, and may require adjuvant radiotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case23755","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T12:22:56Z","timestamp":1709554976000},"source":"Crossref","is-referenced-by-count":0,"title":["Intraspinal cervicothoracic junction chondrosarcoma: illustrative case"],"prefix":"10.3171","volume":"7","author":[{"given":"Matthew T","family":"Carr","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Pain","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Kay","sequence":"additional","affiliation":[{"name":"Department of Pathology, Mount Sinai South Nassau, Oceanside, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K","family":"Houten","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"1","key":"b1","series-title":"Neurosurg Clin N Am.","first-page":"57","article-title":"Chondroma\/chondrosarcoma of the spine","volume":"19","author":"McLoughlin GS","year":"2008","unstructured":"McLoughlin GS, Sciubba DM, Wolinsky JP Chondroma\/chondrosarcoma of the spine. Neurosurg Clin N Am. 2008;19(1):57\u201363."},{"issue":"4","key":"b2","series-title":"Curr Opin Oncol.","first-page":"371","article-title":"Update on chondrosarcomas","volume":"19","author":"Chow WA","year":"2007","unstructured":"Chow WA Update on chondrosarcomas. Curr Opin Oncol. 2007;19(4):371\u2013376."},{"key":"b3","series-title":"F1000Res.","first-page":"F1000 Faculty Rev-1826","article-title":"Chondrosarcoma: biology, genetics, and epigenetics","volume":"7","author":"Chow WA","year":"2018","unstructured":"Chow WA Chondrosarcoma: biology, genetics, and epigenetics. F1000Res. 2018;7:F1000 Faculty Rev-1826."},{"key":"b4","series-title":"Sarcoma.","first-page":"378957","article-title":"Spinal chondrosarcoma: a review","volume":"2011","author":"Katonis P","year":"2011","unstructured":"Katonis P, Alpantaki K, Michail K, et\u00a0al. Spinal chondrosarcoma: a review. Sarcoma. 2011;2011:378957."},{"issue":"5","key":"b5","series-title":"J Pediatr Hematol Oncol.","first-page":"e188","article-title":"Intraspinal mesenchymal chondrosarcoma in a 14-year-old patient: diagnostic and therapeutic problems in relation to the review of literature","volume":"34","author":"Obuchowicz AK","year":"2012","unstructured":"Obuchowicz AK, Szumera-Cie\u0107kiewicz A, Ptaszy\u0144ski K, et\u00a0al. Intraspinal mesenchymal chondrosarcoma in a 14-year-old patient: diagnostic and therapeutic problems in relation to the review of literature. J Pediatr Hematol Oncol. 2012;34(5):e188\u2013e192."},{"issue":"1","key":"b6","series-title":"World J Surg Oncol.","first-page":"203","article-title":"Primary intraspinal dumbbell-shaped mesenchymal chondrosarcoma with massive calcifications: a case report and review of the literature","volume":"14","author":"Chen S","year":"2016","unstructured":"Chen S, Wang Y, Su G, Chen B, Lin D Primary intraspinal dumbbell-shaped mesenchymal chondrosarcoma with massive calcifications: a case report and review of the literature. World J Surg Oncol. 2016;14(1):203."},{"issue":"1","key":"b7","series-title":"Orthop Clin North Am.","first-page":"21","article-title":"Primary malignant tumors of the spine","volume":"40","author":"Sundaresan N","year":"2009","unstructured":"Sundaresan N, Rosen G, Boriani S Primary malignant tumors of the spine. Orthop Clin North Am. 2009;40(1):21\u201336, v."},{"issue":"5","key":"b8","series-title":"J Korean Neurosurg Soc.","first-page":"468","article-title":"Primary spinal dumbbell-shaped mesenchymal chondrosarcoma located intradurally and extradurally","volume":"50","author":"Bae GS","year":"2011","unstructured":"Bae GS, Choi SW, Youm JY, Kim SH Primary spinal dumbbell-shaped mesenchymal chondrosarcoma located intradurally and extradurally. J Korean Neurosurg Soc. 2011;50(5):468\u2013471."},{"issue":"1","key":"b9","series-title":"BMC Neurol.","first-page":"112","article-title":"Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review","volume":"22","author":"Chen M","year":"2022","unstructured":"Chen M, Lai Q Primary intra- and extradural extramedullary mesenchymal chondrosarcoma with isolated punctate calcification: case report and literature review. BMC Neurol. 2022;22(1):112."},{"key":"b10","series-title":"Surg Neurol Int.","first-page":"95","article-title":"Intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature","volume":"11","author":"Gopakumar S","year":"2020","unstructured":"Gopakumar S, Steele WJ, Muir M, Bhogani Z, Britz G Intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature. Surg Neurol Int. 2020;11:95."},{"issue":"4","key":"b11","series-title":"Ann Thorac Surg.","first-page":"586","article-title":"Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum","volume":"50","author":"Ricci C","year":"1990","unstructured":"Ricci C, Rendina EA, Venuta F, Pescarmona EO, Gagliardi F Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum. 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BMC Neurol. 2022;22(1):112."},{"key":"b10","series-title":"Surg Neurol Int.","first-page":"95","article-title":"Intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature","volume":"11","author":"Gopakumar S","year":"2020","unstructured":"Gopakumar S, Steele WJ, Muir M, Bhogani Z, Britz G Intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature. Surg Neurol Int. 2020;11:95."},{"issue":"4","key":"b11","series-title":"Ann Thorac Surg.","first-page":"586","article-title":"Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum","volume":"50","author":"Ricci C","year":"1990","unstructured":"Ricci C, Rendina EA, Venuta F, Pescarmona EO, Gagliardi F Diagnostic imaging and surgical treatment of dumbbell tumors of the mediastinum. Ann Thorac Surg. 1990;50(4):586\u2013589."},{"issue":"4","key":"b12","series-title":"Rare Tumors.","first-page":"5586","article-title":"Extraskeletal myxoid chondrosarcoma presenting as an intradural spinal mass: report of a rare clinical presentation with an emphasis on differential diagnostic considerations","volume":"6","author":"Rao P","year":"2014","unstructured":"Rao P, Colen RR, Bruner JM, Meis JM Extraskeletal myxoid chondrosarcoma presenting as an intradural spinal mass: report of a rare clinical presentation with an emphasis on differential diagnostic considerations. Rare Tumors. 2014;6(4):5586."},{"key":"b13","series-title":"Int J Surg Case Rep.","first-page":"106985","article-title":"Rare presentation of intra-spinal extradural grade 1 chondrosarcoma: a case report","volume":"94","author":"Moghamis IS","year":"2022","unstructured":"Moghamis IS, Alamlih MI, Alhardallo MA, Al Hyassat S, Abdelsalam S, Baco A Rare presentation of intra-spinal extradural grade 1 chondrosarcoma: a case report. Int J Surg Case Rep. 2022;94:106985."},{"issue":"9","key":"b14","series-title":"J Clin Neurosci.","first-page":"958","article-title":"Unusual dumbbell tumours of the mediastinum and thoracic spine","volume":"13","author":"Kilic D","year":"2006","unstructured":"Kilic D, Erdogan B, Sener L, Sahin E, Caner H, Hatipoglu A Unusual dumbbell tumours of the mediastinum and thoracic spine. J Clin Neurosci. 2006;13(9):958\u2013962."},{"issue":"1","key":"b15","series-title":"Scand J Thorac Cardiovasc Surg.","first-page":"47","article-title":"Management of dumbbell tumours. 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