{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T22:41:29Z","timestamp":1776465689856,"version":"3.51.2"},"reference-count":62,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"24","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2024,12,9]]},"abstract":"\n BACKGROUND<\/jats:title>\n Treatment of pediatric craniopharyngioma requires a multidisciplinary approach to counsel patients and families on the spectrum of treatment options, including biopsy, radiation, and\/or resection. Gross-total resection can avoid radiation and its long-term comorbidities. In very young patients, this is of particular importance but is especially challenging because of anatomical considerations.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n A 23-month-old boy was found to have a partially calcified and cystic sellar and suprasellar mass. A fully endoscopic endonasal transtuberculum and transsellar approach was performed for gross-total resection of a subdiaphragmatic adamantinomatous craniopharyngioma. Postoperatively, the patient was diagnosed with panhypopituitarism with diabetes insipidus, though without other hypothalamic dysfunction or new visual deficits. To date, there is no evidence of tumor recurrence.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n In a high-volume center with an experienced multidisciplinary skull base team, endoscopic endonasal approaches to sellar and suprasellar pathology in children younger than 2 years can be safely performed. A smaller nasal cavity and lack of sinus aeration necessitate wide exposure via bone removal and complete opening of the sinuses to enable an adequate working corridor to perform not only tumor resection but also reconstruction. Safe gross-total resection can avoid, or at least delay, radiation and its long-term morbidity when performed in a developing child.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE24209<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case24209","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T01:50:37Z","timestamp":1733709037000},"source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic endonasal resection of a craniopharyngioma in a 23-month-old patient: illustrative case"],"prefix":"10.3171","volume":"8","author":[{"given":"Jessica","family":"Eaton","sequence":"first","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spencer","family":"Raub","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Ronsley","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology, Oncology & BMT, Seattle Children\u2019s Hospital and the University of Washington, Seattle, Washington"},{"name":"Seattle Children\u2019s Hospital Research Institute, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian L.","family":"Roth","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Endocrinology, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Ermoian","sequence":"additional","affiliation":[{"name":"Departments of Radiation Oncology, University of Washington, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seth D.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Departments of Center for Respiratory Biology and Therapeutics, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel N.","family":"Emerson","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"},{"name":"Departments of Neurological Surgery, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"},{"name":"Departments of Neurological Surgery, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Lee","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"},{"name":"Departments of Neurological Surgery, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randall A.","family":"Bly","sequence":"additional","affiliation":[{"name":"Departments of Otolaryngology\/Head and Neck Surgery, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Ruzevick","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery, University of Washington, Seattle, Washington"},{"name":"Departments of Neurological Surgery, Seattle Children\u2019s Hospital, Seattle, Washington"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"3","key":"bib1","series-title":"Endocr Rev","first-page":"513","article-title":"Craniopharyngioma","volume":"35","author":"M\u00fcller","year":"2014","unstructured":"M\u00fcller HL. 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Endoscopic endonasal surgery for resection of giant craniopharyngioma in a toddler\u2014multimodal presurgical planning, surgical technique, and management of complications: 2-dimensional operative video. Oper Neurosurg (Hagerstown). 2020;19(1):E68-E69."},{"issue":"1","key":"bib4","series-title":"Neurosurg Focus","first-page":"E6","article-title":"Endoscopic endonasal surgery outcomes for pediatric craniopharyngioma: a systematic review","volume":"48","author":"Soldozy","year":"2020","unstructured":"Soldozy SYeghyayan MYa\u011fmurlu K, et al. Endoscopic endonasal surgery outcomes for pediatric craniopharyngioma: a systematic review. Neurosurg Focus. 2020;48(1):E6."},{"issue":"11","key":"bib5","series-title":"Laryngoscope","first-page":"2451","article-title":"Pediatric nasoseptal flap reconstruction for suprasellar approaches","volume":"125","author":"Ghosh","year":"2015","unstructured":"Ghosh AHatten KLearned KO, et al. Pediatric nasoseptal flap reconstruction for suprasellar approaches. Laryngoscope. 2015;125(11):2451-2456."},{"issue":"6","key":"bib6","series-title":"Pediatr Neurosurg","first-page":"519","article-title":"Applications of endoscopic endonasal surgery in early childhood: a case series","volume":"56","author":"McDowell","year":"2021","unstructured":"McDowell MMChiang MAbou-Al-Shaar H, et al. Applications of endoscopic endonasal surgery in early childhood: a case series. Pediatr Neurosurg. 2021;56(6):519-528."},{"issue":"4","key":"bib7","series-title":"Laryngoscope","first-page":"832","article-title":"Lack of sphenoid pneumatization does not affect endoscopic endonasal pediatric skull base surgery outcomes","volume":"129","author":"Kuan","year":"2019","unstructured":"Kuan ECKaufman ACLerner D, et al. Lack of sphenoid pneumatization does not affect endoscopic endonasal pediatric skull base surgery outcomes. 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