{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:19:18Z","timestamp":1787768358709,"version":"build-2784847793"},"reference-count":68,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"13","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2024,9,23]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Rathke\u2019s cleft cysts (RCCs) are benign fluid-filled cysts that develop in the pituitary gland because of the abnormal embryological development of Rathke\u2019s pouch. Most RCCs are small and asymptomatic; however, they can present with symptoms or documented growth, sometimes prompting surgical treatment. For smaller asymptomatic lesions, an unknown proportion demonstrates regression over time. This study describes 3 cases of spontaneous RCC regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>Three patients with a diagnosis of RCC demonstrated an average decrease of 78% in cyst volume over a mean interval of 3.7 months. One patient experienced the resolution of chronic headaches, whereas the other 2 patients had persistent headaches and endocrinopathies at follow-up. A systematic review included 9 studies that reported results from observational cohorts of patients with RCC, totaling 619 observed patients, with 158 (25.5%) patients demonstrating spontaneous cyst regression. In the patients with cyst regression, the majority had a resolution of symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>A substantial proportion of RCC patients managed nonsurgically demonstrated spontaneous regression. There is a role for the conservative management of RCCs in patients without significant symptoms, and surveillance should continue for a minimum of 5 years to confirm cyst stability. For patients undergoing planned surgery, same-day or recent imaging is recommended to prevent operating on involuted RCCs.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE24268\">https:\/\/thejns.org\/doi\/10.3171\/CASE24268<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case24268","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T02:44:04Z","timestamp":1727059444000},"source":"Crossref","is-referenced-by-count":2,"title":["Spontaneous regression of Rathke\u2019s cleft cysts with conservative management: patient series"],"prefix":"10.3171","volume":"8","author":[{"given":"Benjamin","family":"Fixman","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery, Keck School of University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Racheal","family":"Peterson","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Keck School of University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Shiroishi","sequence":"additional","affiliation":[{"name":"Departments of Radiology, Keck School of University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Keck School of University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Zada","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Keck School of University of Southern California, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"bib1","series-title":"BMJ Case Rep","first-page":"bcr2012006943","article-title":"A case of symptomatic Rathke\u2019s cyst","volume":"2013","author":"Naik","year":"2013","unstructured":"Naik VDThakore NR. A case of symptomatic Rathke\u2019s cyst. BMJ Case Rep. 2013;2013:bcr2012006943."},{"issue":"1","key":"bib2","series-title":"Neurosurg Focus","first-page":"E1","article-title":"Rathke cleft cysts: a review of clinical and surgical management","volume":"31","author":"Zada","year":"2011","unstructured":"Zada G. Rathke cleft cysts: a review of clinical and surgical management. Neurosurg Focus. 2011;31(1):E1."},{"issue":"1","key":"bib3","series-title":"Radiology","first-page":"161","article-title":"Incidental pituitary lesions in 1,000 unselected autopsy specimens","volume":"193","author":"Teramoto","year":"1994","unstructured":"Teramoto AHirakawa KSanno NOsamura Y. Incidental pituitary lesions in 1,000 unselected autopsy specimens. Radiology. 1994;193(1):161-164."},{"issue":"4","key":"bib4","series-title":"Pituitary","first-page":"362","article-title":"Rathke\u2019s cleft cysts: a 6-year experience of surgery vs. observation with comparative volumetric analysis","volume":"22","author":"Barkhoudarian","year":"2019","unstructured":"Barkhoudarian GPalejwala SKAnsari S, et al. Rathke\u2019s cleft cysts: a 6-year experience of surgery vs. observation with comparative volumetric analysis. Pituitary. 2019;22(4):362-371."},{"issue":"2","key":"bib5","series-title":"Pituitary","first-page":"258","article-title":"A study on clinical outcomes of Rathke\u2019s cleft cyst in patients managed conservatively","volume":"25","author":"Chong","year":"2022","unstructured":"Chong GYCTan KCBLau EYF, et al. A study on clinical outcomes of Rathke\u2019s cleft cyst in patients managed conservatively. Pituitary. 2022;25(2):258-266."},{"issue":"10","key":"bib6","series-title":"J Clin Endocrinol Metab","first-page":"3943","article-title":"A case for conservative management: characterizing the natural history of radiographically diagnosed Rathke cleft cysts","volume":"100","author":"Culver","year":"2015","unstructured":"Culver SAGrober YOrnan DA, et al. A case for conservative management: characterizing the natural history of radiographically diagnosed Rathke cleft cysts. J Clin Endocrinol Metab. 2015;100(10):3943-3948."},{"issue":"2","key":"bib7","series-title":"Brain Tumor Res Treat","first-page":"58","article-title":"Spontaneous involution of Rathke\u2019s cleft cysts without visual symptoms","volume":"4","author":"Kim","year":"2016","unstructured":"Kim CWHwang KJoo JDKim YHHan JHKim CY. Spontaneous involution of Rathke\u2019s cleft cysts without visual symptoms. Brain Tumor Res Treat. 2016;4(2):58-62."},{"issue":"2","key":"bib8","series-title":"Neurosurgery","first-page":"225","article-title":"Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience","volume":"40","author":"Ciric","year":"1997","unstructured":"Ciric IRagin ABaumgartner CPierce D. Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience. Neurosurgery. 1997;40(2):225-236."},{"issue":"2","key":"bib9","series-title":"J Neurosurg","first-page":"350","article-title":"Endonasal transsphenoidal approach to treat pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions of the surgery","volume":"98","author":"Zada","year":"2003","unstructured":"Zada GKelly DFCohan PWang CSwerdloff R. Endonasal transsphenoidal approach to treat pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions of the surgery. J Neurosurg. 2003;98(2):350-358."},{"issue":"6","key":"bib10","series-title":"J Neurosurg","first-page":"1327","article-title":"Spontaneous involution of Rathke cleft cysts: is it rare or just underreported?","volume":"112","author":"Amhaz","year":"2010","unstructured":"Amhaz HHChamoun RBWaguespack SGShah KMcCutcheon IE. Spontaneous involution of Rathke cleft cysts: is it rare or just underreported?. J Neurosurg. 2010;112(6):1327-1332."},{"issue":"2","key":"bib11","series-title":"Clin Endocrinol (Oxf)","first-page":"178","article-title":"Natural history of Rathke\u2019s cleft cysts: a retrospective analysis of a two centres experience","volume":"89","author":"Sala","year":"2018","unstructured":"Sala EMoore JMAmorin A, et al. Natural history of Rathke\u2019s cleft cysts: a retrospective analysis of a two centres experience. Clin Endocrinol (Oxf). 2018;89(2):178-186."},{"issue":"5","key":"bib12","series-title":"Surg Neurol","first-page":"459","article-title":"Management of Rathke\u2019s cleft cysts","volume":"63","author":"Sade","year":"2005","unstructured":"Sade BAlbrecht SAssimakopoulos PV\u00e9zina JLMohr G. Management of Rathke\u2019s cleft cysts. Surg Neurol. 2005;63(5):459-466."},{"issue":"5","key":"bib13","series-title":"J Neurosurg","first-page":"1426","article-title":"Natural course of Rathke\u2019s cleft cysts and risk factors for progression","volume":"138","author":"Kinoshita","year":"2022","unstructured":"Kinoshita YTaguchi AYamasaki FTominaga AArita KHorie N. Natural course of Rathke\u2019s cleft cysts and risk factors for progression. J Neurosurg. 2022;138(5):1426-1432."},{"issue":"6","key":"bib14","series-title":"J Korean Neurosurg Soc","first-page":"723","article-title":"Spontaneously regressed Rathke\u2019s cleft cyst","volume":"62","author":"Lee","year":"2019","unstructured":"Lee CPark SH. Spontaneously regressed Rathke\u2019s cleft cyst. J Korean Neurosurg Soc. 2019;62(6):723-726."},{"issue":"2","key":"bib15","series-title":"Clin Endocrinol (Oxf)","first-page":"151","article-title":"Rathke\u2019s cleft cysts","volume":"76","author":"Trifanescu","year":"2012","unstructured":"Trifanescu RAnsorge OWass JAHGrossman ABKaravitaki N. Rathke\u2019s cleft cysts. Clin Endocrinol (Oxf). 2012;76(2):151-160."},{"key":"bib16","series-title":"World Neurosurg","first-page":"e764","article-title":"Headache resolution after Rathke cleft cyst resection: a meta-analysis","volume":"111","author":"Altuwaijri","year":"2018","unstructured":"Altuwaijri NCote DJLamba N, et al. Headache resolution after Rathke cleft cyst resection: a meta-analysis. World Neurosurg. 2018;111:e764-e772."},{"issue":"2","key":"bib17","series-title":"Neurosurgery","first-page":"250","article-title":"Optimal surgical approaches for Rathke cleft cyst with consideration of endocrine function","volume":"70","author":"Park","year":"2012","unstructured":"Park JKLee EJKim SH. Optimal surgical approaches for Rathke cleft cyst with consideration of endocrine function. Neurosurgery. 2012;70(2SupplOperative):250-256."},{"issue":"3","key":"bib18","series-title":"Neurosurgery","first-page":"837","article-title":"Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts","volume":"67","author":"Wait","year":"2010","unstructured":"Wait SDGarrett MPLittle ASKillory BDWhite WL. Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts. Neurosurgery. 2010;67(3):837-843."},{"issue":"2","key":"bib19","series-title":"J Neurosurg","first-page":"189","article-title":"Surgical outcomes in 118 patients with Rathke cleft cysts","volume":"102","author":"Aho","year":"2005","unstructured":"Aho CJLiu CZelman VCouldwell WTWeiss MH. Surgical outcomes in 118 patients with Rathke cleft cysts. J Neurosurg. 2005;102(2):189-193."},{"issue":"1","key":"bib20","series-title":"Clin Endocrinol (Oxf)","first-page":"54","article-title":"Natural history and surgical outcome of Rathke\u2019s cleft cysts\u2013a study from the Swedish Pituitary Registry","volume":"96","author":"Petersson","year":"2022","unstructured":"Petersson MBerinder KEden Engstr\u00f6m B, et al. Natural history and surgical outcome of Rathke\u2019s cleft cysts\u2013a study from the Swedish Pituitary Registry. Clin Endocrinol (Oxf). 2022;96(1):54-61."},{"issue":"8","key":"bib21","series-title":"J Craniofac Surg","first-page":"e791","article-title":"Spontaneous involution of a Rathke cleft cyst","volume":"27","author":"Cheng","year":"2016","unstructured":"Cheng LGuo PJin PLi HFan MCai E. Spontaneous involution of a Rathke cleft cyst. J Craniofac Surg. 2016;27(8):e791-e793."},{"key":"bib22","series-title":"Case Rep Surg","first-page":"971364","article-title":"Spontaneous involution of a presumably Rathke\u2019s cleft cyst in a patient with slight subclinical hypopituitarism: a case report and review of the literature","volume":"2015","author":"Al Safatli","year":"2015","unstructured":"Al Safatli DKalff RWaschke A. Spontaneous involution of a presumably Rathke\u2019s cleft cyst in a patient with slight subclinical hypopituitarism: a case report and review of the literature. Case Rep Surg. 2015;2015:971364."},{"key":"bib23","series-title":"Surg Neurol Int","first-page":"42","article-title":"Spontaneous involution of a Rathke\u2019s cleft cyst in a patient with normal cortisol secretion","volume":"3","author":"Munich","year":"2012","unstructured":"Munich SALeonardo J. Spontaneous involution of a Rathke\u2019s cleft cyst in a patient with normal cortisol secretion. Surg Neurol Int. 2012;3:42."},{"key":"bib24","series-title":"J Clin Neurosci","first-page":"122","article-title":"Rathke\u2019s cleft cyst: a case report of recurrence and spontaneous involution","volume":"32","author":"Rasmussen","year":"2016","unstructured":"Rasmussen ZAbode-Iyamah KOKirby PGreenlee JDW. Rathke\u2019s cleft cyst: a case report of recurrence and spontaneous involution. J Clin Neurosci. 2016;32:122-125."},{"issue":"1","key":"bib25","series-title":"Clin Imaging","first-page":"15","article-title":"Spontaneous regression of a pituitary cyst: report of two cases","volume":"25","author":"Nishio","year":"2001","unstructured":"Nishio SMorioka TSuzuki SFukui M. Spontaneous regression of a pituitary cyst: report of two cases. Clin Imaging. 2001;25(1):15-17."},{"issue":"4","key":"bib26","series-title":"Neurosurgery","first-page":"644","article-title":"Pituitary hemorrhage into a Rathke\u2019s cleft cyst","volume":"27","author":"Onesti","year":"1990","unstructured":"Onesti STWisniewski TPost KD. Pituitary hemorrhage into a Rathke\u2019s cleft cyst. Neurosurgery. 1990;27(4):644-646."},{"issue":"4","key":"bib27","series-title":"Ann Endocrinol (Paris)","first-page":"260","article-title":"Vanishing Rathke\u2019s cleft cyst","volume":"83","author":"Truong","year":"2022","unstructured":"Truong LUFMarlier BDecoudier BLitr\u00e9 CFBarraud S. Vanishing Rathke\u2019s cleft cyst. Ann Endocrinol (Paris). 2022;83(4):260-262."},{"issue":"8","key":"bib28","series-title":"Neurol Med Chir (Tokyo)","first-page":"592","article-title":"Long-term magnetic resonance imaging follow-up of asymptomatic sellar tumors\u2013their natural history and surgical indications","volume":"39","author":"Igarashi","year":"1999","unstructured":"Igarashi TSaeki NYamaura A. Long-term magnetic resonance imaging follow-up of asymptomatic sellar tumors\u2013their natural history and surgical indications. Neurol Med Chir (Tokyo). 1999;39(8):592-599."},{"issue":"6","key":"bib29","series-title":"J Clin Neurosci","first-page":"524","article-title":"Fluctuating visual field defects in Rathke\u2019s cleft cysts: MRI analysis","volume":"6","author":"Saeki","year":"1999","unstructured":"Saeki NKubota MYamaura AIshige N. Fluctuating visual field defects in Rathke\u2019s cleft cysts: MRI analysis. J Clin Neurosci. 1999;6(6):524-527."},{"issue":"8","key":"bib30","series-title":"No Shinkei Geka Neurol Surg","first-page":"755","article-title":"A case of spontaneous rupture of a suprasellar cystic mass [Article in Japanese]","volume":"29","author":"Terao","year":"2001","unstructured":"Terao TSawauchi SHashimoto TMiyazaki YAkiba YAbe T. A case of spontaneous rupture of a suprasellar cystic mass [Article in Japanese]. No Shinkei Geka Neurol Surg. 2001;29(8):755-758."},{"issue":"2","key":"bib31","series-title":"Eur J Endocrinol","first-page":"123","article-title":"A survey of pituitary incidentaloma in Japan","volume":"149","author":"Sanno","year":"2003","unstructured":"Sanno NOyama KTahara STeramoto AKato Y. A survey of pituitary incidentaloma in Japan. Eur J Endocrinol. 2003;149(2):123-127."},{"key":"bib32","series-title":"Case Rep Endocrinol","first-page":"549262","article-title":"Spontaneous rupture, disappearance, and reaccumulation of a Rathke\u2019s cleft cyst","volume":"2011","author":"Maniec","year":"2011","unstructured":"Maniec KWatson JC. Spontaneous rupture, disappearance, and reaccumulation of a Rathke\u2019s cleft cyst. Case Rep Endocrinol. 2011;2011:549262."},{"issue":"3","key":"bib33","series-title":"J Neurosurg Pediatr","first-page":"308","article-title":"Presentation and outcomes in surgically and conservatively managed pediatric Rathke cleft cysts","volume":"21","author":"Shepard","year":"2018","unstructured":"Shepard MJElzoghby MAKiehna ENPayne SCJane JA. Presentation and outcomes in surgically and conservatively managed pediatric Rathke cleft cysts. J Neurosurg Pediatr. 2018;21(3):308-314."},{"issue":"6","key":"bib34","series-title":"Ann Endocrinol (Paris)","first-page":"626","article-title":"Spontaneous involution of a Rathke cleft cyst","volume":"82","author":"Salle","year":"2021","unstructured":"Salle LTeissier-Cl\u00e9ment MPMas RBoncoeur-Martel MPSalle H. Spontaneous involution of a Rathke cleft cyst. Ann Endocrinol (Paris). 2021;82(6):626-628."},{"key":"bib1","series-title":"BMJ Case Rep","first-page":"bcr2012006943","article-title":"A case of symptomatic Rathke\u2019s cyst","volume":"2013","author":"Naik","year":"2013","unstructured":"Naik VDThakore NR. A case of symptomatic Rathke\u2019s cyst. BMJ Case Rep. 2013;2013:bcr2012006943."},{"issue":"1","key":"bib2","series-title":"Neurosurg Focus","first-page":"E1","article-title":"Rathke cleft cysts: a review of clinical and surgical management","volume":"31","author":"Zada","year":"2011","unstructured":"Zada G. Rathke cleft cysts: a review of clinical and surgical management. Neurosurg Focus. 2011;31(1):E1."},{"issue":"1","key":"bib3","series-title":"Radiology","first-page":"161","article-title":"Incidental pituitary lesions in 1,000 unselected autopsy specimens","volume":"193","author":"Teramoto","year":"1994","unstructured":"Teramoto AHirakawa KSanno NOsamura Y. Incidental pituitary lesions in 1,000 unselected autopsy specimens. Radiology. 1994;193(1):161-164."},{"issue":"4","key":"bib4","series-title":"Pituitary","first-page":"362","article-title":"Rathke\u2019s cleft cysts: a 6-year experience of surgery vs. observation with comparative volumetric analysis","volume":"22","author":"Barkhoudarian","year":"2019","unstructured":"Barkhoudarian GPalejwala SKAnsari S, et al. Rathke\u2019s cleft cysts: a 6-year experience of surgery vs. observation with comparative volumetric analysis. Pituitary. 2019;22(4):362-371."},{"issue":"2","key":"bib5","series-title":"Pituitary","first-page":"258","article-title":"A study on clinical outcomes of Rathke\u2019s cleft cyst in patients managed conservatively","volume":"25","author":"Chong","year":"2022","unstructured":"Chong GYCTan KCBLau EYF, et al. A study on clinical outcomes of Rathke\u2019s cleft cyst in patients managed conservatively. Pituitary. 2022;25(2):258-266."},{"issue":"10","key":"bib6","series-title":"J Clin Endocrinol Metab","first-page":"3943","article-title":"A case for conservative management: characterizing the natural history of radiographically diagnosed Rathke cleft cysts","volume":"100","author":"Culver","year":"2015","unstructured":"Culver SAGrober YOrnan DA, et al. A case for conservative management: characterizing the natural history of radiographically diagnosed Rathke cleft cysts. J Clin Endocrinol Metab. 2015;100(10):3943-3948."},{"issue":"2","key":"bib7","series-title":"Brain Tumor Res Treat","first-page":"58","article-title":"Spontaneous involution of Rathke\u2019s cleft cysts without visual symptoms","volume":"4","author":"Kim","year":"2016","unstructured":"Kim CWHwang KJoo JDKim YHHan JHKim CY. Spontaneous involution of Rathke\u2019s cleft cysts without visual symptoms. Brain Tumor Res Treat. 2016;4(2):58-62."},{"issue":"2","key":"bib8","series-title":"Neurosurgery","first-page":"225","article-title":"Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience","volume":"40","author":"Ciric","year":"1997","unstructured":"Ciric IRagin ABaumgartner CPierce D. Complications of transsphenoidal surgery: results of a national survey, review of the literature, and personal experience. Neurosurgery. 1997;40(2):225-236."},{"issue":"2","key":"bib9","series-title":"J Neurosurg","first-page":"350","article-title":"Endonasal transsphenoidal approach to treat pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions of the surgery","volume":"98","author":"Zada","year":"2003","unstructured":"Zada GKelly DFCohan PWang CSwerdloff R. Endonasal transsphenoidal approach to treat pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions of the surgery. J Neurosurg. 2003;98(2):350-358."},{"issue":"6","key":"bib10","series-title":"J Neurosurg","first-page":"1327","article-title":"Spontaneous involution of Rathke cleft cysts: is it rare or just underreported?","volume":"112","author":"Amhaz","year":"2010","unstructured":"Amhaz HHChamoun RBWaguespack SGShah KMcCutcheon IE. Spontaneous involution of Rathke cleft cysts: is it rare or just underreported?. J Neurosurg. 2010;112(6):1327-1332."},{"issue":"2","key":"bib11","series-title":"Clin Endocrinol (Oxf)","first-page":"178","article-title":"Natural history of Rathke\u2019s cleft cysts: a retrospective analysis of a two centres experience","volume":"89","author":"Sala","year":"2018","unstructured":"Sala EMoore JMAmorin A, et al. Natural history of Rathke\u2019s cleft cysts: a retrospective analysis of a two centres experience. Clin Endocrinol (Oxf). 2018;89(2):178-186."},{"issue":"5","key":"bib12","series-title":"Surg Neurol","first-page":"459","article-title":"Management of Rathke\u2019s cleft cysts","volume":"63","author":"Sade","year":"2005","unstructured":"Sade BAlbrecht SAssimakopoulos PV\u00e9zina JLMohr G. Management of Rathke\u2019s cleft cysts. Surg Neurol. 2005;63(5):459-466."},{"issue":"5","key":"bib13","series-title":"J Neurosurg","first-page":"1426","article-title":"Natural course of Rathke\u2019s cleft cysts and risk factors for progression","volume":"138","author":"Kinoshita","year":"2022","unstructured":"Kinoshita YTaguchi AYamasaki FTominaga AArita KHorie N. Natural course of Rathke\u2019s cleft cysts and risk factors for progression. J Neurosurg. 2022;138(5):1426-1432."},{"issue":"6","key":"bib14","series-title":"J Korean Neurosurg Soc","first-page":"723","article-title":"Spontaneously regressed Rathke\u2019s cleft cyst","volume":"62","author":"Lee","year":"2019","unstructured":"Lee CPark SH. Spontaneously regressed Rathke\u2019s cleft cyst. J Korean Neurosurg Soc. 2019;62(6):723-726."},{"issue":"2","key":"bib15","series-title":"Clin Endocrinol (Oxf)","first-page":"151","article-title":"Rathke\u2019s cleft cysts","volume":"76","author":"Trifanescu","year":"2012","unstructured":"Trifanescu RAnsorge OWass JAHGrossman ABKaravitaki N. Rathke\u2019s cleft cysts. Clin Endocrinol (Oxf). 2012;76(2):151-160."},{"key":"bib16","series-title":"World Neurosurg","first-page":"e764","article-title":"Headache resolution after Rathke cleft cyst resection: a meta-analysis","volume":"111","author":"Altuwaijri","year":"2018","unstructured":"Altuwaijri NCote DJLamba N, et al. Headache resolution after Rathke cleft cyst resection: a meta-analysis. World Neurosurg. 2018;111:e764-e772."},{"issue":"2","key":"bib17","series-title":"Neurosurgery","first-page":"250","article-title":"Optimal surgical approaches for Rathke cleft cyst with consideration of endocrine function","volume":"70","author":"Park","year":"2012","unstructured":"Park JKLee EJKim SH. Optimal surgical approaches for Rathke cleft cyst with consideration of endocrine function. Neurosurgery. 2012;70(2SupplOperative):250-256."},{"issue":"3","key":"bib18","series-title":"Neurosurgery","first-page":"837","article-title":"Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts","volume":"67","author":"Wait","year":"2010","unstructured":"Wait SDGarrett MPLittle ASKillory BDWhite WL. Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts. Neurosurgery. 2010;67(3):837-843."},{"issue":"2","key":"bib19","series-title":"J Neurosurg","first-page":"189","article-title":"Surgical outcomes in 118 patients with Rathke cleft cysts","volume":"102","author":"Aho","year":"2005","unstructured":"Aho CJLiu CZelman VCouldwell WTWeiss MH. Surgical outcomes in 118 patients with Rathke cleft cysts. J Neurosurg. 2005;102(2):189-193."},{"issue":"1","key":"bib20","series-title":"Clin Endocrinol (Oxf)","first-page":"54","article-title":"Natural history and surgical outcome of Rathke\u2019s cleft cysts\u2013a study from the Swedish Pituitary Registry","volume":"96","author":"Petersson","year":"2022","unstructured":"Petersson MBerinder KEden Engstr\u00f6m B, et al. Natural history and surgical outcome of Rathke\u2019s cleft cysts\u2013a study from the Swedish Pituitary Registry. Clin Endocrinol (Oxf). 2022;96(1):54-61."},{"issue":"8","key":"bib21","series-title":"J Craniofac Surg","first-page":"e791","article-title":"Spontaneous involution of a Rathke cleft cyst","volume":"27","author":"Cheng","year":"2016","unstructured":"Cheng LGuo PJin PLi HFan MCai E. Spontaneous involution of a Rathke cleft cyst. J Craniofac Surg. 2016;27(8):e791-e793."},{"key":"bib22","series-title":"Case Rep Surg","first-page":"971364","article-title":"Spontaneous involution of a presumably Rathke\u2019s cleft cyst in a patient with slight subclinical hypopituitarism: a case report and review of the literature","volume":"2015","author":"Al Safatli","year":"2015","unstructured":"Al Safatli DKalff RWaschke A. Spontaneous involution of a presumably Rathke\u2019s cleft cyst in a patient with slight subclinical hypopituitarism: a case report and review of the literature. Case Rep Surg. 2015;2015:971364."},{"key":"bib23","series-title":"Surg Neurol Int","first-page":"42","article-title":"Spontaneous involution of a Rathke\u2019s cleft cyst in a patient with normal cortisol secretion","volume":"3","author":"Munich","year":"2012","unstructured":"Munich SALeonardo J. Spontaneous involution of a Rathke\u2019s cleft cyst in a patient with normal cortisol secretion. Surg Neurol Int. 2012;3:42."},{"key":"bib24","series-title":"J Clin Neurosci","first-page":"122","article-title":"Rathke\u2019s cleft cyst: a case report of recurrence and spontaneous involution","volume":"32","author":"Rasmussen","year":"2016","unstructured":"Rasmussen ZAbode-Iyamah KOKirby PGreenlee JDW. Rathke\u2019s cleft cyst: a case report of recurrence and spontaneous involution. 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