{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:39:31Z","timestamp":1772757571379,"version":"3.50.1"},"reference-count":36,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"8","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2024,8,19]]},"abstract":"\n BACKGROUND<\/jats:title>\n A novel pelvic fixation screw fusion device (iFuse Bedrock Granite implant) was designed to promote bony fusion through self-harvesting fenestrations throughout the outer screw shank. Bone on-growth and in-growth using this design have been demonstrated in a sheep model, but data from human subjects have not been reported. A 66-year-old medically complex female with 2 prior spine fusions developed spondylodiscitis cephalad to a prior fusion, requiring the removal of instrumentation, which included screw fusion devices.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n Within this case report, the authors present a novel bone-preserving technique for the removal of well-fixed screw fusion devices. One screw backed out with a driver, and the other 3 had to be trephined out. One screw sheared off the T30 torque driver, implying a removal torque greater than 270 inch-lbs (30.5 Nm). In addition, the removed implants were analyzed using microcomputed tomography (micro-CT) and demonstrated bone on-growth, in-growth, and through-growth in all 4 screws.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n Micro-CT clearly demonstrated osseous integration of the screw fusion devices and provided significant support for the use of these implants for lumbopelvic fixation. The authors\u2019 hope is that the novel bone-preserving technique will help other surgeons when faced with the difficult removal of well-fixed screw fusion devices.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE24274<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case24274","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T02:47:12Z","timestamp":1724035632000},"source":"Crossref","is-referenced-by-count":2,"title":["Removal of infected bone in-growth pelvic fixation implants and microcomputed tomography analysis of osseous integration: illustrative case"],"prefix":"10.3171","volume":"8","author":[{"given":"Bradley S","family":"Spence","sequence":"first","affiliation":[{"name":"Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew W","family":"Godlewski","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason J","family":"Haselhuhn","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen E","family":"Jones","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota"},{"name":"Departments of Neurosurgery, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W","family":"Polly","sequence":"additional","affiliation":[{"name":"Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota"},{"name":"Departments of Neurosurgery, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"4","key":"bib1","series-title":"Clin Spine Surg","first-page":"169","article-title":"Sacroiliac joint degeneration and pain after spinal arthrodesis: a systematic review","volume":"36","author":"Manzetti","year":"2023","unstructured":"Manzetti MRuffilli ABarile F, et al. Sacroiliac joint degeneration and pain after spinal arthrodesis: a systematic review. Clin Spine Surg. 2023;36(4):169-182."},{"key":"bib2","series-title":"World Neurosurgery","first-page":"e15","article-title":"Randomized trial of augmented pelvic fixation in patients undergoing thoracolumbar fusion for","volume":"187","author":"Polly","year":"2024","unstructured":"Polly DMundis GEastlack R, et al. Randomized trial of augmented pelvic fixation in patients undergoing thoracolumbar fusion for adult spine deformity: initial results from a multicenter randomized trial. World Neurosurgery. 2024;187:e15-e27."},{"key":"bib3","article-title":"Osseointegration and fixation opportunities of sacroiliac hardware: a preclinical evaluation in a large animal model","author":"Polly","unstructured":"Polly DWGardner MJWills D, et al. Osseointegration and fixation opportunities of sacroiliac hardware: a preclinical evaluation in a large animal model. Invited podium presentation at: Annual Meeting of the Orthopedic Research Society; February 10\u201314. Dallas, TX. Paper 0234."},{"issue":"5","key":"bib4","series-title":"Epidemiol Infect","first-page":"653","article-title":"Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002-2003","volume":"136","author":"Grammatico","year":"2008","unstructured":"Grammatico LBaron SRusch E, et al. Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002-2003. Epidemiol Infect. 2008;136(5):653-660."},{"issue":"3","key":"bib5","series-title":"Neurosurg Clin N Am","first-page":"339","article-title":"Vertebral osteomyelitis","volume":"17","author":"Jaramillo-de la Torre","year":"2006","unstructured":"Jaramillo-de la Torre JJBohinski RJKuntz CIV. Vertebral osteomyelitis. Neurosurg Clin N Am. 2006;17(3):339-351."},{"issue":"1","key":"bib6","series-title":"J Infect Public Health","first-page":"5","article-title":"Pyogenic spondylodiscitis: an overview","volume":"3","author":"Skaf","year":"2010","unstructured":"Skaf GSDomloj NTFehlings MG, et al. Pyogenic spondylodiscitis: an overview. J Infect Public Health. 2010;3(1):5-16."},{"issue":"1","key":"bib7","series-title":"Semin Arthritis Rheum","first-page":"10","article-title":"Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics","volume":"39","author":"Mylona","year":"2009","unstructured":"Mylona ESamarkos MKakalou EFanourgiakis PSkoutelis A. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum. 2009;39(1):10-17."},{"key":"bib8","series-title":"J Neurosurg Spine","first-page":"758","article-title":"Beta-lactam\u2013resistant Staphylococcus aureus in spinal osteomyelitis and spondylodiscitis: current landscape","author":"Saad Berreta","unstructured":"Saad Berreta RZhang HAlsoof D, et al. Beta-lactam\u2013resistant Staphylococcus aureus in spinal osteomyelitis and spondylodiscitis: current landscape in antibiotic resistance, treatment, and complications. J Neurosurg Spine. 2023;38(6):758-763."},{"issue":"1","key":"bib9","series-title":"BMC Infect Dis","first-page":"39","article-title":"The importance of the bacterial spectrum in the clinical diagnostics and management of patients with spontaneous pyogenic spondylodiscitis and isolated spinal epidural empyema: a 20-year cohort study at a single spine center","volume":"24","author":"Hijazi","year":"2024","unstructured":"Hijazi MMSiepmann TEl-Battrawy I, et al. The importance of the bacterial spectrum in the clinical diagnostics and management of patients with spontaneous pyogenic spondylodiscitis and isolated spinal epidural empyema: a 20-year cohort study at a single spine center. BMC Infect Dis. 2024;24(1):39."},{"issue":"5","key":"bib10","series-title":"Infection","first-page":"1017","article-title":"Influence of microbiological diagnosis on the clinical course of spondylodiscitis","volume":"49","author":"Stangenberg","year":"2021","unstructured":"Stangenberg MMende KCMohme M, et al. Influence of microbiological diagnosis on the clinical course of spondylodiscitis. Infection. 2021;49(5):1017-1027."},{"issue":"4","key":"bib11","series-title":"Eur Spine J","first-page":"751","article-title":"Predicting the need for surgical intervention in patients with spondylodiscitis: the Brighton Spondylodiscitis Score (BSDS)","volume":"28","author":"Appalanaidu","year":"2019","unstructured":"Appalanaidu NShafafy RGee C, et al. Predicting the need for surgical intervention in patients with spondylodiscitis: the Brighton Spondylodiscitis Score (BSDS). Eur Spine J. 2019;28(4):751-761."},{"issue":"2","key":"bib12","series-title":"Eur Rev Med Pharmacol Sci","first-page":"117","article-title":"A systematic review: characteristics, complications and treatment of spondylodiscitis","volume":"23","author":"Gentile","year":"2019","unstructured":"Gentile LBenazzo FDe Rosa F, et al. A systematic review: characteristics, complications and treatment of spondylodiscitis. Eur Rev Med Pharmacol Sci. 2019;23(2):117-128."},{"issue":"suppl","key":"bib13","series-title":"Eur Spine J","first-page":"479","article-title":"New classification for the treatment of pyogenic spondylodiscitis: validation study on a population of 250 patients with a follow-up of 2 years","volume":"26","author":"Pola","year":"2017","unstructured":"Pola EAutore GFormica VM, et al. 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Clin Orthop Relat Res. 1992;285:13-29."},{"issue":"(8):","key":"bib18","series-title":"J Orthop res","first-page":"1820","article-title":"Osseointegration of minimally invasive sacroiliac joint fixation implants\u2013a human","volume":"42","author":"Randers","year":"2024;","unstructured":"Randers EKibsg\u00e5rd TNogueira LP, et al. Osseointegration of minimally invasive sacroiliac joint fixation implants\u2013a human retrieval study. J Orthop res. 2024;42(8):1820-1830."},{"issue":"4","key":"bib1","series-title":"Clin Spine Surg","first-page":"169","article-title":"Sacroiliac joint degeneration and pain after spinal arthrodesis: a systematic review","volume":"36","author":"Manzetti","year":"2023","unstructured":"Manzetti MRuffilli ABarile F, et al. Sacroiliac joint degeneration and pain after spinal arthrodesis: a systematic review. Clin Spine Surg. 2023;36(4):169-182."},{"key":"bib2","series-title":"World Neurosurgery","first-page":"e15","article-title":"Randomized trial of augmented pelvic fixation in patients undergoing thoracolumbar fusion for","volume":"187","author":"Polly","year":"2024","unstructured":"Polly DMundis GEastlack R, et al. Randomized trial of augmented pelvic fixation in patients undergoing thoracolumbar fusion for adult spine deformity: initial results from a multicenter randomized trial. World Neurosurgery. 2024;187:e15-e27."},{"key":"bib3","article-title":"Osseointegration and fixation opportunities of sacroiliac hardware: a preclinical evaluation in a large animal model","author":"Polly","unstructured":"Polly DWGardner MJWills D, et al. Osseointegration and fixation opportunities of sacroiliac hardware: a preclinical evaluation in a large animal model. Invited podium presentation at: Annual Meeting of the Orthopedic Research Society; February 10\u201314. Dallas, TX. Paper 0234."},{"issue":"5","key":"bib4","series-title":"Epidemiol Infect","first-page":"653","article-title":"Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002-2003","volume":"136","author":"Grammatico","year":"2008","unstructured":"Grammatico LBaron SRusch E, et al. Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 2002-2003. Epidemiol Infect. 2008;136(5):653-660."},{"issue":"3","key":"bib5","series-title":"Neurosurg Clin N Am","first-page":"339","article-title":"Vertebral osteomyelitis","volume":"17","author":"Jaramillo-de la Torre","year":"2006","unstructured":"Jaramillo-de la Torre JJBohinski RJKuntz CIV. Vertebral osteomyelitis. Neurosurg Clin N Am. 2006;17(3):339-351."},{"issue":"1","key":"bib6","series-title":"J Infect Public Health","first-page":"5","article-title":"Pyogenic spondylodiscitis: an overview","volume":"3","author":"Skaf","year":"2010","unstructured":"Skaf GSDomloj NTFehlings MG, et al. Pyogenic spondylodiscitis: an overview. J Infect Public Health. 2010;3(1):5-16."},{"issue":"1","key":"bib7","series-title":"Semin Arthritis Rheum","first-page":"10","article-title":"Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics","volume":"39","author":"Mylona","year":"2009","unstructured":"Mylona ESamarkos MKakalou EFanourgiakis PSkoutelis A. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum. 2009;39(1):10-17."},{"key":"bib8","series-title":"J Neurosurg Spine","first-page":"758","article-title":"Beta-lactam\u2013resistant Staphylococcus aureus in spinal osteomyelitis and spondylodiscitis: current landscape","author":"Saad Berreta","unstructured":"Saad Berreta RZhang HAlsoof D, et al. Beta-lactam\u2013resistant Staphylococcus aureus in spinal osteomyelitis and spondylodiscitis: current landscape in antibiotic resistance, treatment, and complications. J Neurosurg Spine. 2023;38(6):758-763."},{"issue":"1","key":"bib9","series-title":"BMC Infect Dis","first-page":"39","article-title":"The importance of the bacterial spectrum in the clinical diagnostics and management of patients with spontaneous pyogenic spondylodiscitis and isolated spinal epidural empyema: a 20-year cohort study at a single spine center","volume":"24","author":"Hijazi","year":"2024","unstructured":"Hijazi MMSiepmann TEl-Battrawy I, et al. The importance of the bacterial spectrum in the clinical diagnostics and management of patients with spontaneous pyogenic spondylodiscitis and isolated spinal epidural empyema: a 20-year cohort study at a single spine center. BMC Infect Dis. 2024;24(1):39."},{"issue":"5","key":"bib10","series-title":"Infection","first-page":"1017","article-title":"Influence of microbiological diagnosis on the clinical course of spondylodiscitis","volume":"49","author":"Stangenberg","year":"2021","unstructured":"Stangenberg MMende KCMohme M, et al. Influence of microbiological diagnosis on the clinical course of spondylodiscitis. Infection. 2021;49(5):1017-1027."},{"issue":"4","key":"bib11","series-title":"Eur Spine J","first-page":"751","article-title":"Predicting the need for surgical intervention in patients with spondylodiscitis: the Brighton Spondylodiscitis Score (BSDS)","volume":"28","author":"Appalanaidu","year":"2019","unstructured":"Appalanaidu NShafafy RGee C, et al. Predicting the need for surgical intervention in patients with spondylodiscitis: the Brighton Spondylodiscitis Score (BSDS). Eur Spine J. 2019;28(4):751-761."},{"issue":"2","key":"bib12","series-title":"Eur Rev Med Pharmacol Sci","first-page":"117","article-title":"A systematic review: characteristics, complications and treatment of spondylodiscitis","volume":"23","author":"Gentile","year":"2019","unstructured":"Gentile LBenazzo FDe Rosa F, et al. A systematic review: characteristics, complications and treatment of spondylodiscitis. Eur Rev Med Pharmacol Sci. 2019;23(2):117-128."},{"issue":"suppl","key":"bib13","series-title":"Eur Spine J","first-page":"479","article-title":"New classification for the treatment of pyogenic spondylodiscitis: validation study on a population of 250 patients with a follow-up of 2 years","volume":"26","author":"Pola","year":"2017","unstructured":"Pola EAutore GFormica VM, et al. New classification for the treatment of pyogenic spondylodiscitis: validation study on a population of 250 patients with a follow-up of 2 years. Eur Spine J. 2017;26(suppl 4):479-488."},{"issue":"8","key":"bib14","series-title":"Eur Spine J","first-page":"1837","article-title":"Failure modes in conservative and surgical management of infectious spondylodiscitis","volume":"22","author":"Valancius","year":"2013","unstructured":"Valancius KHansen ESH\u00f8y KHelmig PNiedermann BB\u00fcnger C. Failure modes in conservative and surgical management of infectious spondylodiscitis. Eur Spine J. 2013;22(8):1837-1844."},{"issue":"3","key":"bib15","series-title":"Infection","first-page":"503","article-title":"Outcome-related co-factors in 105 cases of vertebral osteomyelitis in a tertiary care hospital","volume":"42","author":"Loibl","year":"2014","unstructured":"Loibl MStoyanov LDoenitz C, et al. Outcome-related co-factors in 105 cases of vertebral osteomyelitis in a tertiary care hospital. Infection. 2014;42(3):503-510."},{"issue":"2","key":"bib16","series-title":"Eur Spine J","first-page":"461","article-title":"Non-specific spondylodiscitis: a new perspective for surgical treatment","volume":"31","author":"Giampaolini","year":"2022","unstructured":"Giampaolini NBerdini MRotini MPalmisani RSpecchia NMartiniani M. Non-specific spondylodiscitis: a new perspective for surgical treatment. Eur Spine J. 2022;31(2):461-472."},{"key":"bib17","series-title":"Clin Orthop Relat Res","first-page":"13","article-title":"Quantification of implant micromotion, strain shielding, and bone resorption with porous-coated anatomic medullary locking femoral prostheses","volume":"285","author":"Engh","year":"1992","unstructured":"Engh CAO\u2019Connor DJasty MMcGovern TFBobyn JDHarris WH. Quantification of implant micromotion, strain shielding, and bone resorption with porous-coated anatomic medullary locking femoral prostheses. Clin Orthop Relat Res. 1992;285:13-29."},{"issue":"(8):","key":"bib18","series-title":"J Orthop res","first-page":"1820","article-title":"Osseointegration of minimally invasive sacroiliac joint fixation implants\u2013a human","volume":"42","author":"Randers","year":"2024;","unstructured":"Randers EKibsg\u00e5rd TNogueira LP, et al. Osseointegration of minimally invasive sacroiliac joint fixation implants\u2013a human retrieval study. 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