{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T13:58:57Z","timestamp":1769781537972,"version":"3.49.0"},"reference-count":32,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"22","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2024,11,25]]},"abstract":"\n BACKGROUND<\/jats:title>\n Meningiomas are common primary intracranial tumors, with associated intratumoral hemorrhage being a rare but serious complication requiring prompt diagnosis for optimal outcomes. Although spontaneous bleeding in benign meningiomas is rare, it can lead to subarachnoid hemorrhage, subdural hematoma, or intratumoral\/intracerebral hemorrhage, significantly increasing morbidity and mortality. Advanced imaging and recognition of radiographic hemorrhage patterns are crucial for accurate diagnosis. Treatment is case specific, as surgical intervention is preferred for symptomatic patients, while observation might be adequate for asymptomatic cases. When surgery is not feasible, stereotactic radiotherapy or chemotherapy, which is used only as salvage therapy, is considered.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n The authors present the case of a 78-year-old male with a history of recurrent falls. Imaging studies revealed a posttraumatic subdural hematoma and an intratumoral hemorrhage within a left frontotemporal meningioma. The patient was managed conservatively, showing significant improvement over 6 months. Notably, there was a marked reduction in both tumor size and intratumoral hemorrhage during follow-up.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n This case highlights the importance of adopting case-specific management strategies for hemorrhagic complications associated with meningiomas. While surgery is crucial for symptomatic meningiomas, this case demonstrates that conservative methods can be effective for a subset of symptomatic patients with stable clinical conditions and manageable intracranial bleeding.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE24322<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case24322","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T13:04:51Z","timestamp":1732539891000},"source":"Crossref","is-referenced-by-count":0,"title":["A rare case of posttraumatic subdural hematoma and intratumoral hemorrhage in a left frontotemporal meningioma: a conservative approach with longitudinal follow-up. Illustrative case"],"prefix":"10.3171","volume":"8","author":[{"given":"Mansour","family":"Khaleel","sequence":"first","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, State of Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Sayyed Ahmad","sequence":"additional","affiliation":[{"name":"Department of Medicine, Al-Quds University, Jerusalem, State of Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Ayyad","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Rutgers New Jersey Medical School, Newark, New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amer","family":"Abu Al Ragheb","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Abdali Hospital, Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"bib1","series-title":"World Neurosurg","first-page":"217","article-title":"Intracranial hemorrhage from meningioma: 2 novel risk factors","volume":"135","author":"Pressman","year":"2020","unstructured":"Pressman EPenn DPatel NJ. Intracranial hemorrhage from meningioma: 2 novel risk factors. World Neurosurg. 2020;135:217-221."},{"key":"bib2","series-title":"World Neurosurg","first-page":"599","article-title":"Pathogenetic mechanisms of intratumoral hemorrhage in meningioma: the role of microvascular differentiation","volume":"95","author":"Grasso","year":"2016","unstructured":"Grasso GLandi AAlafaci C. Pathogenetic mechanisms of intratumoral hemorrhage in meningioma: the role of microvascular differentiation. World Neurosurg. 2016;95:599-600."},{"issue":"4","key":"bib3","series-title":"Neurosurgery","first-page":"437","article-title":"Spontaneous intracranial hemorrhage caused by brain tumor: its incidence and clinical significance","volume":"10","author":"Wakai","year":"1982","unstructured":"Wakai SYamakawa KManaka STakakura K. Spontaneous intracranial hemorrhage caused by brain tumor: its incidence and clinical significance. Neurosurgery. 1982;10(4):437-444."},{"key":"bib4","series-title":"World Neurosurg","first-page":"246","article-title":"Intratumoral hemorrhage within petrous meningioma","volume":"117","author":"Entezami","year":"2018","unstructured":"Entezami PRiccio AKenning TJ. Intratumoral hemorrhage within petrous meningioma. World Neurosurg. 2018;117:246-248."},{"issue":"2","key":"bib5","series-title":"Acta Neurochir (Wien)","first-page":"165","article-title":"Meningioma manifesting intracerebral hemorrhage: a possible mechanism of hemorrhage","volume":"142","author":"Kim","year":"2000","unstructured":"Kim DGPark CKPaek SH, et al. Meningioma manifesting intracerebral hemorrhage: a possible mechanism of hemorrhage. Acta Neurochir (Wien). 2000;142(2):165-168."},{"issue":"3","key":"bib6","series-title":"J Neurosurg","first-page":"473","article-title":"Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome","volume":"103","author":"Bo\u015dnjak","year":"2005","unstructured":"Bo\u015dnjak RDerham CPopovi\u0107 MRavnik J. Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome. J Neurosurg. 2005;103(3):473-484."},{"issue":"2","key":"bib7","series-title":"J Neurooncol","first-page":"183","article-title":"Molecular pathogenesis of meningiomas","volume":"70","author":"Perry","year":"2004","unstructured":"Perry AGutmann DHReifenberger G. Molecular pathogenesis of meningiomas. J Neurooncol. 2004;70(2):183-202."},{"issue":"8","key":"bib8","series-title":"J Neurol Neurosurg Psychiatry","first-page":"725","article-title":"Hemorrhage associated with meningioma: a case report and review of the literature","volume":"43","author":"Helle","year":"1980","unstructured":"Helle TLConley FK. Hemorrhage associated with meningioma: a case report and review of the literature. J Neurol Neurosurg Psychiatry. 1980;43(8):725-729."},{"issue":"4","key":"bib9","series-title":"J Neurosurg","first-page":"437","article-title":"Meningiomas causing spontaneous intracranial hematomas","volume":"45","author":"Modesti","year":"1976","unstructured":"Modesti LMBinet EFCollins GH. Meningiomas causing spontaneous intracranial hematomas. J Neurosurg. 1976;45(4):437-441."},{"issue":"11","key":"bib10","series-title":"Cureus","first-page":"e11486","article-title":"Spontaneous or traumatic intratumoral hemorrhage? A rare presentation of parafalcine meningioma","volume":"12","author":"Dang","unstructured":"Dang DDMugge LAwan ODang JShenai M. Spontaneous or traumatic intratumoral hemorrhage? A rare presentation of parafalcine meningioma. Cureus. 2020;12(11):e11486."},{"issue":"2","key":"bib11","series-title":"Neuro Oncol","first-page":"278","article-title":"A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas","volume":"22","author":"Islim","year":"2020","unstructured":"Islim AIKolamunnage-Dona RMohan M, et al. A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas. Neuro Oncol. 2020;22(2):278-289."},{"issue":"21","key":"bib12","series-title":"Future Oncol","first-page":"2161","article-title":"An overview of meningiomas","volume":"14","author":"Buerki","year":"2018","unstructured":"Buerki RAHorbinski CMKruser THorowitz PMJames CDLukas RV. An overview of meningiomas. Future Oncol. 2018;14(21):2161-2177."},{"issue":"2A","key":"bib13","series-title":"Arq Neuro Psiquiatr","first-page":"308","article-title":"Subdural haematoma in a patient with meningioma","volume":"67","author":"Worm","year":"2009","unstructured":"Worm PVFerreira MPFerreira NPCechetti F. Subdural haematoma in a patient with meningioma. Arq Neuro Psiquiatr. 2009;67(2A):308-310."},{"key":"bib14","series-title":"Front Oncol","first-page":"565582","article-title":"Review of atypical and anaplastic meningiomas: classification, molecular biology, and management","volume":"10","author":"Wilson","year":"2020","unstructured":"Wilson TAHuang LRamanathan D, et al. Review of atypical and anaplastic meningiomas: classification, molecular biology, and management. Front Oncol. 2020;10:565582."},{"issue":"6","key":"bib15","series-title":"Acta Neuropathol","first-page":"803","article-title":"The 2016 World Health Organization Classification of Tumours of the Central Nervous System: a summary","volume":"131","author":"Louis","year":"2016","unstructured":"Louis DNPerry AReifenberger G, et al. The 2016 World Health Organization Classification of Tumours of the Central Nervous System: a summary. Acta Neuropathol. 2016;131(6):803-820."},{"issue":"11","key":"bib16","series-title":"Neuro-Oncol","first-page":"1821","article-title":"EANO guideline on the diagnosis and management of meningiomas","volume":"23","author":"Goldbrunner","year":"2021","unstructured":"Goldbrunner RStavrinou PJenkinson MD, et al. EANO guideline on the diagnosis and management of meningiomas. Neuro-Oncol. 2021;23(11):1821-1834."},{"key":"bib1","series-title":"World Neurosurg","first-page":"217","article-title":"Intracranial hemorrhage from meningioma: 2 novel risk factors","volume":"135","author":"Pressman","year":"2020","unstructured":"Pressman EPenn DPatel NJ. Intracranial hemorrhage from meningioma: 2 novel risk factors. World Neurosurg. 2020;135:217-221."},{"key":"bib2","series-title":"World Neurosurg","first-page":"599","article-title":"Pathogenetic mechanisms of intratumoral hemorrhage in meningioma: the role of microvascular differentiation","volume":"95","author":"Grasso","year":"2016","unstructured":"Grasso GLandi AAlafaci C. Pathogenetic mechanisms of intratumoral hemorrhage in meningioma: the role of microvascular differentiation. World Neurosurg. 2016;95:599-600."},{"issue":"4","key":"bib3","series-title":"Neurosurgery","first-page":"437","article-title":"Spontaneous intracranial hemorrhage caused by brain tumor: its incidence and clinical significance","volume":"10","author":"Wakai","year":"1982","unstructured":"Wakai SYamakawa KManaka STakakura K. Spontaneous intracranial hemorrhage caused by brain tumor: its incidence and clinical significance. Neurosurgery. 1982;10(4):437-444."},{"key":"bib4","series-title":"World Neurosurg","first-page":"246","article-title":"Intratumoral hemorrhage within petrous meningioma","volume":"117","author":"Entezami","year":"2018","unstructured":"Entezami PRiccio AKenning TJ. Intratumoral hemorrhage within petrous meningioma. World Neurosurg. 2018;117:246-248."},{"issue":"2","key":"bib5","series-title":"Acta Neurochir (Wien)","first-page":"165","article-title":"Meningioma manifesting intracerebral hemorrhage: a possible mechanism of hemorrhage","volume":"142","author":"Kim","year":"2000","unstructured":"Kim DGPark CKPaek SH, et al. Meningioma manifesting intracerebral hemorrhage: a possible mechanism of hemorrhage. Acta Neurochir (Wien). 2000;142(2):165-168."},{"issue":"3","key":"bib6","series-title":"J Neurosurg","first-page":"473","article-title":"Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome","volume":"103","author":"Bo\u015dnjak","year":"2005","unstructured":"Bo\u015dnjak RDerham CPopovi\u0107 MRavnik J. Spontaneous intracranial meningioma bleeding: clinicopathological features and outcome. J Neurosurg. 2005;103(3):473-484."},{"issue":"2","key":"bib7","series-title":"J Neurooncol","first-page":"183","article-title":"Molecular pathogenesis of meningiomas","volume":"70","author":"Perry","year":"2004","unstructured":"Perry AGutmann DHReifenberger G. Molecular pathogenesis of meningiomas. J Neurooncol. 2004;70(2):183-202."},{"issue":"8","key":"bib8","series-title":"J Neurol Neurosurg Psychiatry","first-page":"725","article-title":"Hemorrhage associated with meningioma: a case report and review of the literature","volume":"43","author":"Helle","year":"1980","unstructured":"Helle TLConley FK. Hemorrhage associated with meningioma: a case report and review of the literature. J Neurol Neurosurg Psychiatry. 1980;43(8):725-729."},{"issue":"4","key":"bib9","series-title":"J Neurosurg","first-page":"437","article-title":"Meningiomas causing spontaneous intracranial hematomas","volume":"45","author":"Modesti","year":"1976","unstructured":"Modesti LMBinet EFCollins GH. Meningiomas causing spontaneous intracranial hematomas. J Neurosurg. 1976;45(4):437-441."},{"issue":"11","key":"bib10","series-title":"Cureus","first-page":"e11486","article-title":"Spontaneous or traumatic intratumoral hemorrhage? A rare presentation of parafalcine meningioma","volume":"12","author":"Dang","unstructured":"Dang DDMugge LAwan ODang JShenai M. Spontaneous or traumatic intratumoral hemorrhage? A rare presentation of parafalcine meningioma. Cureus. 2020;12(11):e11486."},{"issue":"2","key":"bib11","series-title":"Neuro Oncol","first-page":"278","article-title":"A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas","volume":"22","author":"Islim","year":"2020","unstructured":"Islim AIKolamunnage-Dona RMohan M, et al. A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas. Neuro Oncol. 2020;22(2):278-289."},{"issue":"21","key":"bib12","series-title":"Future Oncol","first-page":"2161","article-title":"An overview of meningiomas","volume":"14","author":"Buerki","year":"2018","unstructured":"Buerki RAHorbinski CMKruser THorowitz PMJames CDLukas RV. An overview of meningiomas. Future Oncol. 2018;14(21):2161-2177."},{"issue":"2A","key":"bib13","series-title":"Arq Neuro Psiquiatr","first-page":"308","article-title":"Subdural haematoma in a patient with meningioma","volume":"67","author":"Worm","year":"2009","unstructured":"Worm PVFerreira MPFerreira NPCechetti F. Subdural haematoma in a patient with meningioma. Arq Neuro Psiquiatr. 2009;67(2A):308-310."},{"key":"bib14","series-title":"Front Oncol","first-page":"565582","article-title":"Review of atypical and anaplastic meningiomas: classification, molecular biology, and management","volume":"10","author":"Wilson","year":"2020","unstructured":"Wilson TAHuang LRamanathan D, et al. Review of atypical and anaplastic meningiomas: classification, molecular biology, and management. Front Oncol. 2020;10:565582."},{"issue":"6","key":"bib15","series-title":"Acta Neuropathol","first-page":"803","article-title":"The 2016 World Health Organization Classification of Tumours of the Central Nervous System: a summary","volume":"131","author":"Louis","year":"2016","unstructured":"Louis DNPerry AReifenberger G, et al. The 2016 World Health Organization Classification of Tumours of the Central Nervous System: a summary. Acta Neuropathol. 2016;131(6):803-820."},{"issue":"11","key":"bib16","series-title":"Neuro-Oncol","first-page":"1821","article-title":"EANO guideline on the diagnosis and management of meningiomas","volume":"23","author":"Goldbrunner","year":"2021","unstructured":"Goldbrunner RStavrinou PJenkinson MD, et al. EANO guideline on the diagnosis and management of meningiomas. 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