{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T07:22:20Z","timestamp":1770189740989,"version":"3.49.0"},"reference-count":36,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"11","license":[{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,3,17]]},"abstract":"\n BACKGROUND<\/jats:title>\n Cerebellar liponeurocytoma is a rare, low-grade neoplasm (WHO grade 2) characterized by neuronal or neurocytic differentiation and variable glial differentiation with lipoma-like alterations. First described in 1978 and recognized in the WHO classification in 2000, it presents significant challenges in radiological and pathological differentiation. This differentiation is crucial to avoid unnecessary or deleterious treatments.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n The patient presented with symptoms including headache, dizziness, hiccups, nausea, vomiting, tinnitus, and left-sided ataxia. Imaging revealed a heterogeneous lesion in the left cerebellopontine angle. Resection was performed via a left suboccipital retrosigmoid approach, resulting in significant improvement in axial and appendicular ataxia, although left-sided anacusis persisted. Histopathological analysis confirmed cerebellar liponeurocytoma showing hypercellularity, with neurocytic cells containing lipid accumulations. Immunohistochemical analysis revealed diffuse expression of synaptophysin and focal expression of glial fibrillary acidic protein, with a Ki-67 proliferation index of 7%.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n Cerebellar liponeurocytoma is a rare tumor requiring accurate histopathological differentiation to determine the appropriate treatment. Resection remains the mainstay of treatment, with postoperative radiotherapy potentially reducing recurrence. Multidisciplinary follow-up is crucial for managing residual symptoms and monitoring for recurrence. This case aligns with existing literature and underscores the importance of comprehensive diagnostic and therapeutic approaches to improve patient outcomes.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE24521<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case24521","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T03:01:55Z","timestamp":1742180515000},"source":"Crossref","is-referenced-by-count":0,"title":["Cerebellar liponeurocytoma: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7435-8668","authenticated-orcid":true,"given":"Halisson R.","family":"de Andrade","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9012-8731","authenticated-orcid":true,"given":"Fernanda","family":"Fenner","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina Pochio","family":"Vasques","sequence":"additional","affiliation":[{"name":"Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Matos","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"Pathology Department, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcio S.","family":"Rassi","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean G.","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"},{"name":"Division of Neurosurgery, Department of Surgery, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1016-7624","authenticated-orcid":true,"given":"Carmen L\u00facia Penteado","family":"Lancellotti","sequence":"additional","affiliation":[{"name":"Pathology Department, Santa Casa de S\u00e3o Paulo School of Medical Sciences, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"bib1","volume":"6","year":"2021","unstructured":"WHO Classification of Tumours: Central Nervous System Tumours. 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