{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:23:21Z","timestamp":1770114201026,"version":"3.49.0"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,1,20]]},"abstract":"\n BACKGROUND<\/jats:title>\n Intravascular injection of liquid adhesive hemostats is a rare but serious complication that can result in cerebral thromboembolism.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n A 64-year-old female underwent orbitozygomatic craniotomy for posterior communicating artery aneurysm clipping with the routine use of a flowable hemostatic agent during extradural dissection. After placement of the aneurysm clip, flow was confirmed through the parent vessel and nearby branches. On postoperative day 1, the patient was found to have superficial middle cerebral vein thrombosis with retrograde embolization and subsequent hemorrhagic infarction of the temporal lobe.<\/jats:p>\n Eight prior cases of intracranial infarction or hemorrhage secondary to thrombosis with intravascular liquid adhesive were identified. With a craniotomy approach, the transverse and sigmoid sinuses were the most common sites of thrombosis, and the vertebral and basilar arteries had the highest incidence of thrombosis after cervical fusion.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n Intravascular injection of liquid adhesive agents can result in cerebral venous thrombosis, typically of a dural venous sinus. This may present following retrograde embolization, which has not previously been reported. The choice of hemostat, surgical approach, nearby vasculature, and anatomical variations should be carefully considered in the operative management of neurosurgical patients.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE24607<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case24607","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T15:53:55Z","timestamp":1737388435000},"source":"Crossref","is-referenced-by-count":0,"title":["Retrograde thrombosis of the superficial sylvian vein following liquid adhesive hemostat use during craniotomy: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"given":"Gabrielle E. A.","family":"Hovis","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of California, Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordan","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California, Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Lockwood","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California, Irvine, Orange, California"},{"name":"Department of Neurosurgery, Tulane University, New Orleans, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank P. K.","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California, Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"3","key":"bib1","series-title":"J Neurosurg","first-page":"576","article-title":"Iatrogenic cerebral venous sinus occlusion with flowable topical hemostatic matrix","volume":"115","author":"Singleton","year":"2011","unstructured":"Singleton RHJankowitz BTWecht DAGardner PA. Iatrogenic cerebral venous sinus occlusion with flowable topical hemostatic matrix. J Neurosurg. 2011;115(3):576-583."},{"issue":"6","key":"bib2","series-title":"J Vasc Surg","first-page":"2189","article-title":"Systematic review of hemostatic agents used in vascular surgery","volume":"73","author":"Allotey","year":"2021","unstructured":"Allotey JKKing AHKumins NH, et al. Systematic review of hemostatic agents used in vascular surgery. J Vasc Surg. 2021;73(6):2189-2197."},{"issue":"1","key":"bib3","series-title":"BMC Surg","first-page":"68","article-title":"A systematic review on the use of topical hemostats in trauma and emergency surgery","volume":"18","author":"Chiara","year":"2018","unstructured":"Chiara OCimbanassi SBellanova G, et al. A systematic review on the use of topical hemostats in trauma and emergency surgery. BMC Surg. 2018;18(1):68."},{"issue":"6","key":"bib4","series-title":"Clin Appl Thromb Hemost","first-page":"572","article-title":"A randomized trial of aprotinin-free fibrin sealant versus absorbable hemostat","volume":"17","author":"Fischer","year":"2011","unstructured":"Fischer CPWood CGShen J, et al. A randomized trial of aprotinin-free fibrin sealant versus absorbable hemostat. Clin Appl Thromb Hemost. 2011;17(6):572-577."},{"issue":"2","key":"bib5","series-title":"Am J Forensic Med Pathol","first-page":"182","article-title":"Two cases of cerebral infarcts caused by topical hemostatic agent embolism","volume":"42","author":"Coss","year":"2021","unstructured":"Coss DJTlomak WCochran E. Two cases of cerebral infarcts caused by topical hemostatic agent embolism. Am J Forensic Med Pathol. 2021;42(2):182-185."},{"issue":"1","key":"bib6","series-title":"Case Rep Neurol","first-page":"7","article-title":"Postoperative textiloma mimicking intracranial rebleeding in a patient with spontaneous hemorrhage: case report and review of the literature","volume":"12","author":"Montemurro","year":"2020","unstructured":"Montemurro NMurrone DRomanelli BIerardi A. Postoperative textiloma mimicking intracranial rebleeding in a patient with spontaneous hemorrhage: case report and review of the literature. Case Rep Neurol. 2020;12(1):7-12."},{"issue":"10","key":"bib7","series-title":"Neurol Med Chir (Tokyo)","first-page":"733","article-title":"Cerebral vein disorders and postoperative brain damage associated with the pterional approach in aneurysm surgery","volume":"32","author":"Kageyama","year":"1992","unstructured":"Kageyama YFukuda KKobayashi S, et al. Cerebral vein disorders and postoperative brain damage associated with the pterional approach in aneurysm surgery. Neurol Med Chir (Tokyo). 1992;32(10):733-738."},{"issue":"8","key":"bib8","series-title":"AJNR Am J Neuroradiol","first-page":"2019","article-title":"Incidence of superficial sylvian vein compromise and postoperative effects on CT imaging after surgical clipping of middle cerebral artery aneurysms","volume":"26","author":"Dean","year":"2005","unstructured":"Dean BLWallace RCZabramski JMPitt AMBird CRSpetzler RF. Incidence of superficial sylvian vein compromise and postoperative effects on CT imaging after surgical clipping of middle cerebral artery aneurysms. AJNR Am J Neuroradiol. 2005;26(8):2019-2026."},{"key":"bib9","series-title":"Principles of Neurological Surgery","first-page":"268","article-title":"Anterior circulation aneurysms","author":"Mason","year":"2018","unstructured":"Mason ABarrow DL. Anterior circulation aneurysms. In: Ellenbogen RSekhar LNKitchen NDBrito da Silva H, eds. Principles of Neurological Surgery. 4th ed. Elsevier; 2018:268-270."},{"key":"bib10","series-title":"Swaiman's Pediatric Neurology","first-page":"858","article-title":"Sinovenous thrombosis in infants and children","author":"Billinghurst","year":"2017","unstructured":"Billinghurst LMoharir M. Sinovenous thrombosis in infants and children. In: Swaiman KFAshwal SFerriero DM, et al, eds. Swaiman's Pediatric Neurology. 6th ed. 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Incidence of superficial sylvian vein compromise and postoperative effects on CT imaging after surgical clipping of middle cerebral artery aneurysms. AJNR Am J Neuroradiol. 2005;26(8):2019-2026."},{"key":"bib9","series-title":"Principles of Neurological Surgery","first-page":"268","article-title":"Anterior circulation aneurysms","author":"Mason","year":"2018","unstructured":"Mason ABarrow DL. Anterior circulation aneurysms. In: Ellenbogen RSekhar LNKitchen NDBrito da Silva H, eds. Principles of Neurological Surgery. 4th ed. Elsevier; 2018:268-270."},{"key":"bib10","series-title":"Swaiman's Pediatric Neurology","first-page":"858","article-title":"Sinovenous thrombosis in infants and children","author":"Billinghurst","year":"2017","unstructured":"Billinghurst LMoharir M. Sinovenous thrombosis in infants and children. In: Swaiman KFAshwal SFerriero DM, et al, eds. Swaiman's Pediatric Neurology. 6th ed. 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Incidence of thromboembolic events after use of gelatin-thrombin-based hemostatic matrix during intracranial tumor surgery. 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