{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T23:28:51Z","timestamp":1770161331084,"version":"3.49.0"},"reference-count":32,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"16","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,4,21]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The purpose of this case report is to highlight the presentation, radiographic challenges, and clinical decision-making prior to operative intervention in an 84-year-old man with a delayed recurrence of diffuse large B-cell lymphoma (DLBCL) in a rare location of the intradural extramedullary space of the cervical spine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>The authors report the case of a cervical intradural extramedullary neoplasm in an 84-year-old male who presented with ataxic gait and right-sided weakness. The patient has a history of testicular DLBCL. Initial MRI revealed a mass at C6\u20137 mimicking the appearance of either a schwannoma or a meningioma. He underwent resective surgery of the neoplasm, which proved to be a recurrence of DLBCL by histopathology and immunohistochemistry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Diagnosing rare malignancies like lymphoma in the spine requires considering the patient\u2019s history, as imaging alone might not allow distinguishing between different tumor types. For patients with a history of lymphoma, malignant recurrence in the spine should be considered in the differential diagnosis of solitary spinal masses, even when imaging suggests more common lesions.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE24830\">https:\/\/thejns.org\/doi\/10.3171\/CASE24830<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case24830","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T20:10:26Z","timestamp":1745266226000},"source":"Crossref","is-referenced-by-count":0,"title":["Solitary intradural extramedullary recurrence of testicular diffuse large B-cell lymphoma mimicking a schwannoma: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"given":"Marli","family":"Knox","sequence":"first","affiliation":[{"name":"Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis","family":"Starasoler","sequence":"additional","affiliation":[{"name":"Department of Pathology, JFK Medical Center\u2013Main Campus, Atlantis, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehuda","family":"Herschman","sequence":"additional","affiliation":[{"name":"Palm Beach Neurosurgery, Lake Worth, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"7","key":"bib1","series-title":"Diagnostics (Basel)","first-page":"1254","article-title":"Spinal schwannomatosis mimicking metastatic extramedullary spinal tumor","volume":"13","author":"Nurdillah","year":"2023","unstructured":"Nurdillah IRizuana IHSyazarina SO.Spinal schwannomatosis mimicking metastatic extramedullary spinal tumor. Diagnostics (Basel). 2023;13(7):1254."},{"issue":"2","key":"bib2","series-title":"Korean J Spine","first-page":"71","article-title":"Diffuse large B-cell lymphoma mimicking schwannoma of lumbar spine","volume":"13","author":"Kim","year":"2016","unstructured":"Kim SKLee SHKim ESEoh W.Diffuse large B-cell lymphoma mimicking schwannoma of lumbar spine. Korean J Spine. 2016;13(2):71-73."},{"issue":"4","key":"bib3","series-title":"J Neurosurg Spine","first-page":"436","article-title":"Solitary intradural extramedullary lymphoma of the cervical spine","volume":"12","author":"Yamashita","year":"2010","unstructured":"Yamashita TSakaura HOshima KIwasaki MYoshikawa H.Solitary intradural extramedullary lymphoma of the cervical spine. J Neurosurg Spine. 2010;12(4):436-439."},{"issue":"2","key":"bib4","series-title":"Radiographics","first-page":"468","article-title":"Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation","volume":"39","author":"Koeller","year":"2019","unstructured":"Koeller KKShih RY.Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation. Radiographics. 2019;39(2):468-490."},{"issue":"suppl 27","key":"bib5","series-title":"Surg Neurol Int","first-page":"S661","article-title":"Surgical management of intradural spinal cord tumors in children and young adults: a single-center experience with 50 patients","volume":"6","author":"\u00d6zkan","year":"2015","unstructured":"\u00d6zkan NJabbarli RWrede KHSurgical management of intradural spinal cord tumors in children and young adults: a single-center experience with 50 patients. Surg Neurol Int. 2015;6(suppl 27):S661-S667."},{"issue":"3","key":"bib6","series-title":"Neuroimaging Clin N Am","first-page":"407","article-title":"Intradural extramedullary tumors and associated syndromes","volume":"33","author":"Puac-Polanco","year":"2023","unstructured":"Puac-Polanco PGuarnizo ACruz JPRodriguez FRTorres CH.Intradural extramedullary tumors and associated syndromes. Neuroimaging Clin N Am. 2023;33(3):407-422."},{"issue":"17","key":"bib7","series-title":"Cancer","first-page":"4220","article-title":"Descriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004-2007","volume":"118","author":"Duong","year":"2012","unstructured":"Duong LMMcCarthy BJMcLendon REDescriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004-2007. Cancer. 2012;118(17):4220-4227."},{"issue":"1","key":"bib8","series-title":"Hematology Am Soc Hematol Educ Program","first-page":"578","article-title":"Secondary CNS relapse in diffuse large B-cell lymphoma: defining high-risk patients and optimization of prophylaxis strategies","volume":"2017","author":"Savage","year":"2017","unstructured":"Savage KJ.Secondary CNS relapse in diffuse large B-cell lymphoma: defining high-risk patients and optimization of prophylaxis strategies. Hematology Am Soc Hematol Educ Program. 2017;2017(1):578-586."},{"issue":"1","key":"bib9","series-title":"Cancer","first-page":"154","article-title":"Testicular lymphoma is associated with a high incidence of extranodal recurrence","volume":"88","author":"Fonseca","year":"2000","unstructured":"Fonseca RHabermann TMColgan JPTesticular lymphoma is associated with a high incidence of extranodal recurrence. Cancer. 2000;88(1):154-161."},{"issue":"1","key":"bib10","series-title":"J Neurosurg Spine","first-page":"61","article-title":"Primary intradural extraarachnoid Hodgkin lymphoma of the cervical spine. Case report","volume":"5","author":"Heran","year":"2006","unstructured":"Heran NSYong RLHeran MSYip SFairholm D.Primary intradural extraarachnoid Hodgkin lymphoma of the cervical spine. Case report. J Neurosurg Spine. 2006;5(1):61-64."},{"key":"bib11","series-title":"J Clin Neurosci","first-page":"122","article-title":"Primary spinal intradural extramedullary lymphoma: a novel management strategy","volume":"35","author":"Do","year":"2017","unstructured":"Do ASSmith GAPace JHdeib AKasliwal MK.Primary spinal intradural extramedullary lymphoma: a novel management strategy. J Clin Neurosci. 2017;35:122-126."},{"key":"bib12","series-title":"Int Med Case Rep J","first-page":"701","article-title":"Primary intradural extramedullary spinal Burkitt\u2019s lymphoma: a case report","volume":"13","author":"Goitom Sereke","year":"2020","unstructured":"Goitom Sereke SBongomin FMuyinda Z.Primary intradural extramedullary spinal Burkitt\u2019s lymphoma: a case report. Int Med Case Rep J. 2020;13:701-705."},{"issue":"1","key":"bib13","series-title":"Spinal Cord Ser Cases","first-page":"53","article-title":"Primary intradural extramedullary spinal Burkitt\u2019s lymphoma mimicking a nerve sheath tumor: a case report","volume":"8","author":"Bansal","year":"2022","unstructured":"Bansal TSahu SSharma MCBorkar S.Primary intradural extramedullary spinal Burkitt\u2019s lymphoma mimicking a nerve sheath tumor: a case report. Spinal Cord Ser Cases. 2022;8(1):53."},{"issue":"2","key":"bib14","series-title":"J Clin Exp Hematop","first-page":"62","article-title":"Intradural extramedullary relapse of peripheral T-cell lymphoma, NOS","volume":"60","author":"Shimazu","year":"2020","unstructured":"Shimazu YSakata ANohgawa M.Intradural extramedullary relapse of peripheral T-cell lymphoma, NOS. J Clin Exp Hematop. 2020;60(2):62-64."},{"issue":"1","key":"bib15","series-title":"Neurosurg Rev","first-page":"1","article-title":"Intradural and extradural spinal metastases","volume":"24","author":"Schick","year":"2001","unstructured":"Schick UMarquardt GLorenz R.Intradural and extradural spinal metastases. Neurosurg Rev. 2001;24(1):1-7."},{"issue":"2","key":"bib16","series-title":"J Craniovertebr Junction Spine","first-page":"58","article-title":"Primary spinal intradural extramedullary lymphoma causing cauda equina syndrome","volume":"3","author":"Cugati","year":"2012","unstructured":"Cugati GSingh MSymss NPPande AVasudevan MCRamamurthi R.Primary spinal intradural extramedullary lymphoma causing cauda equina syndrome. J Craniovertebr Junction Spine. 2012;3(2):58-61."},{"issue":"7","key":"bib1","series-title":"Diagnostics (Basel)","first-page":"1254","article-title":"Spinal schwannomatosis mimicking metastatic extramedullary spinal tumor","volume":"13","author":"Nurdillah","year":"2023","unstructured":"Nurdillah IRizuana IHSyazarina SO.Spinal schwannomatosis mimicking metastatic extramedullary spinal tumor. Diagnostics (Basel). 2023;13(7):1254."},{"issue":"2","key":"bib2","series-title":"Korean J Spine","first-page":"71","article-title":"Diffuse large B-cell lymphoma mimicking schwannoma of lumbar spine","volume":"13","author":"Kim","year":"2016","unstructured":"Kim SKLee SHKim ESEoh W.Diffuse large B-cell lymphoma mimicking schwannoma of lumbar spine. Korean J Spine. 2016;13(2):71-73."},{"issue":"4","key":"bib3","series-title":"J Neurosurg Spine","first-page":"436","article-title":"Solitary intradural extramedullary lymphoma of the cervical spine","volume":"12","author":"Yamashita","year":"2010","unstructured":"Yamashita TSakaura HOshima KIwasaki MYoshikawa H.Solitary intradural extramedullary lymphoma of the cervical spine. J Neurosurg Spine. 2010;12(4):436-439."},{"issue":"2","key":"bib4","series-title":"Radiographics","first-page":"468","article-title":"Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation","volume":"39","author":"Koeller","year":"2019","unstructured":"Koeller KKShih RY.Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation. Radiographics. 2019;39(2):468-490."},{"issue":"suppl 27","key":"bib5","series-title":"Surg Neurol Int","first-page":"S661","article-title":"Surgical management of intradural spinal cord tumors in children and young adults: a single-center experience with 50 patients","volume":"6","author":"\u00d6zkan","year":"2015","unstructured":"\u00d6zkan NJabbarli RWrede KHSurgical management of intradural spinal cord tumors in children and young adults: a single-center experience with 50 patients. Surg Neurol Int. 2015;6(suppl 27):S661-S667."},{"issue":"3","key":"bib6","series-title":"Neuroimaging Clin N Am","first-page":"407","article-title":"Intradural extramedullary tumors and associated syndromes","volume":"33","author":"Puac-Polanco","year":"2023","unstructured":"Puac-Polanco PGuarnizo ACruz JPRodriguez FRTorres CH.Intradural extramedullary tumors and associated syndromes. Neuroimaging Clin N Am. 2023;33(3):407-422."},{"issue":"17","key":"bib7","series-title":"Cancer","first-page":"4220","article-title":"Descriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004-2007","volume":"118","author":"Duong","year":"2012","unstructured":"Duong LMMcCarthy BJMcLendon REDescriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004-2007. Cancer. 2012;118(17):4220-4227."},{"issue":"1","key":"bib8","series-title":"Hematology Am Soc Hematol Educ Program","first-page":"578","article-title":"Secondary CNS relapse in diffuse large B-cell lymphoma: defining high-risk patients and optimization of prophylaxis strategies","volume":"2017","author":"Savage","year":"2017","unstructured":"Savage KJ.Secondary CNS relapse in diffuse large B-cell lymphoma: defining high-risk patients and optimization of prophylaxis strategies. Hematology Am Soc Hematol Educ Program. 2017;2017(1):578-586."},{"issue":"1","key":"bib9","series-title":"Cancer","first-page":"154","article-title":"Testicular lymphoma is associated with a high incidence of extranodal recurrence","volume":"88","author":"Fonseca","year":"2000","unstructured":"Fonseca RHabermann TMColgan JPTesticular lymphoma is associated with a high incidence of extranodal recurrence. Cancer. 2000;88(1):154-161."},{"issue":"1","key":"bib10","series-title":"J Neurosurg Spine","first-page":"61","article-title":"Primary intradural extraarachnoid Hodgkin lymphoma of the cervical spine. Case report","volume":"5","author":"Heran","year":"2006","unstructured":"Heran NSYong RLHeran MSYip SFairholm D.Primary intradural extraarachnoid Hodgkin lymphoma of the cervical spine. Case report. J Neurosurg Spine. 2006;5(1):61-64."},{"key":"bib11","series-title":"J Clin Neurosci","first-page":"122","article-title":"Primary spinal intradural extramedullary lymphoma: a novel management strategy","volume":"35","author":"Do","year":"2017","unstructured":"Do ASSmith GAPace JHdeib AKasliwal MK.Primary spinal intradural extramedullary lymphoma: a novel management strategy. J Clin Neurosci. 2017;35:122-126."},{"key":"bib12","series-title":"Int Med Case Rep J","first-page":"701","article-title":"Primary intradural extramedullary spinal Burkitt\u2019s lymphoma: a case report","volume":"13","author":"Goitom Sereke","year":"2020","unstructured":"Goitom Sereke SBongomin FMuyinda Z.Primary intradural extramedullary spinal Burkitt\u2019s lymphoma: a case report. Int Med Case Rep J. 2020;13:701-705."},{"issue":"1","key":"bib13","series-title":"Spinal Cord Ser Cases","first-page":"53","article-title":"Primary intradural extramedullary spinal Burkitt\u2019s lymphoma mimicking a nerve sheath tumor: a case report","volume":"8","author":"Bansal","year":"2022","unstructured":"Bansal TSahu SSharma MCBorkar S.Primary intradural extramedullary spinal Burkitt\u2019s lymphoma mimicking a nerve sheath tumor: a case report. Spinal Cord Ser Cases. 2022;8(1):53."},{"issue":"2","key":"bib14","series-title":"J Clin Exp Hematop","first-page":"62","article-title":"Intradural extramedullary relapse of peripheral T-cell lymphoma, NOS","volume":"60","author":"Shimazu","year":"2020","unstructured":"Shimazu YSakata ANohgawa M.Intradural extramedullary relapse of peripheral T-cell lymphoma, NOS. J Clin Exp Hematop. 2020;60(2):62-64."},{"issue":"1","key":"bib15","series-title":"Neurosurg Rev","first-page":"1","article-title":"Intradural and extradural spinal metastases","volume":"24","author":"Schick","year":"2001","unstructured":"Schick UMarquardt GLorenz R.Intradural and extradural spinal metastases. Neurosurg Rev. 2001;24(1):1-7."},{"issue":"2","key":"bib16","series-title":"J Craniovertebr Junction Spine","first-page":"58","article-title":"Primary spinal intradural extramedullary lymphoma causing cauda equina syndrome","volume":"3","author":"Cugati","year":"2012","unstructured":"Cugati GSingh MSymss NPPande AVasudevan MCRamamurthi R.Primary spinal intradural extramedullary lymphoma causing cauda equina syndrome. J Craniovertebr Junction Spine. 2012;3(2):58-61."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/16\/article-CASE24830.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/16\/article-CASE24830.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/16\/article-CASE24830.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:38:29Z","timestamp":1770075509000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/16\/article-CASE24830.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,21]]},"references-count":32,"journal-issue":{"issue":"16"},"URL":"https:\/\/doi.org\/10.3171\/case24830","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,21]]}}}