{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:27:46Z","timestamp":1770114466784,"version":"3.49.0"},"reference-count":70,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"22","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,6,2]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Meningiomas represent the most prevalent primary tumors of the central nervous system, with the majority classified as benign (WHO grade I) and exhibiting favorable prognoses. However, a rare subset of meningiomas show malignant behavior, characterized by local invasion and distant metastasis, occurring in less than 1% of cases. Metastatic meningiomas most commonly involve the lungs, bones, liver, and soft tissues, with bone metastases presenting significant diagnostic and therapeutic challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 61-year-old male with a history of recurrent intracranial meningiomas presented with neck pain and digital paresthesia. Imaging studies revealed lesions at the C4 and C5 vertebrae, accompanied by a pathological fracture at C5. Consequently, a C4 and C5 corpectomy with anterior reconstruction was performed. Histomolecular analysis confirmed the presence of an intraosseous anaplastic meningioma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Metastatic meningiomas are an uncommon entity that necessitates a multidisciplinary approach for accurate detection and effective management. The integration of molecular and genetic profiling, along with advanced imaging techniques, may facilitate the identification of high-risk tumors, guide personalized treatment strategies, and ultimately improve patient outcomes.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE24863\">https:\/\/thejns.org\/doi\/10.3171\/CASE24863<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case24863","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T19:46:15Z","timestamp":1749498375000},"source":"Crossref","is-referenced-by-count":0,"title":["Cervical vertebral metastases from a recurrent intracranial anaplastic meningioma: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4736-4426","authenticated-orcid":true,"given":"Grimi","family":"Alessandro","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy"},{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5669-2286","authenticated-orcid":true,"given":"Mario","family":"De Robertis","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy"},{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6081-5963","authenticated-orcid":true,"given":"Ali","family":"Baram","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Capo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1765-863X","authenticated-orcid":true,"given":"Elena","family":"Clerici","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Radiosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethania","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Pathology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4643-6451","authenticated-orcid":true,"given":"Marco","family":"Riva","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy"},{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Pessina","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy"},{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Brembilla","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Fornari","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"12","key":"bib1","series-title":"Neuro Oncol","first-page":"iv1","article-title":"CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013-2017","volume":"22","author":"Ostrom","year":"2020","unstructured":"Ostrom QTPatil NCioffi GWaite KKruchko CBarnholtz-Sloan JS.CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2013-2017. 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J Nucl Med Technol. 2022;50(4):348-352."},{"issue":"9","key":"bib22","series-title":"J Nucl Med","first-page":"1409","article-title":"Peptide receptor radionuclide therapy in advanced refractory meningiomas: efficacy and toxicity in a long follow-up","volume":"65","author":"Severi","year":"2024","unstructured":"Severi SGrassi IBongiovanni APeptide receptor radionuclide therapy in advanced refractory meningiomas: efficacy and toxicity in a long follow-up. J Nucl Med. 2024;65(9):1409-1415."},{"issue":"4","key":"bib23","series-title":"Int J Radiat Oncol Biol Phys","first-page":"868","article-title":"68ga-DOTATATE PET: the future of meningioma treatment","volume":"113","author":"Prasad","year":"2022","unstructured":"Prasad RNPerlow HKBovi J68ga-DOTATATE PET: the future of meningioma treatment. Int J Radiat Oncol Biol Phys. 2022;113(4):868-871."},{"issue":"5","key":"bib24","series-title":"Neuro Oncol","first-page":"796","article-title":"A molecularly integrated grade for meningioma","volume":"24","author":"Driver","year":"2022","unstructured":"Driver JHoffman SETavakol SA molecularly integrated grade for meningioma. Neuro Oncol. 2022;24(5):796-808."},{"issue":"7874","key":"bib25","series-title":"Nature","first-page":"119","article-title":"A clinically applicable integrative molecular classification of meningiomas","volume":"597","author":"Nassiri","year":"2021","unstructured":"Nassiri FLiu JPatil VA clinically applicable integrative molecular classification of meningiomas. 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