{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:59:45Z","timestamp":1785423585438,"version":"3.56.0"},"reference-count":10,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"17","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,4,28]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Mycobacterium abscessus<\/jats:italic>\n                      , a rapidly growing nontuberculous mycobacterium, is known for its resistance to standard antimicrobial therapies and its association with pulmonary and soft tissue infections, particularly in immunocompromised patients. Spinal infections caused by\n                      <jats:italic>M. abscessus<\/jats:italic>\n                      are rare, with limited reported cases, especially in immunocompetent individuals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>\n                      The authors report the case of a 76-year-old male who developed a deep-seated\n                      <jats:italic>M. abscessus<\/jats:italic>\n                      infection following lumbar spinal fusion surgery. Despite an initial postoperative recovery, the patient experienced progressive symptoms requiring multiple surgical washouts, removal of spinal hardware, and prolonged multidrug antibiotic therapy. Diagnostic challenges were compounded by the organism\u2019s resistance and the emergence of a possible underlying lymphoproliferative disorder. Comprehensive microbiological testing, including acid-fast bacilli cultures, identified the pathogen and guided targeted therapy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>\n                      This case highlights the diagnostic and therapeutic complexities of managing multidrug-resistant pathogens like\n                      <jats:italic>M. abscessus<\/jats:italic>\n                      in postoperative settings. Early microbiological testing, multidisciplinary collaboration, and individualized treatment strategies were critical to the patient\u2019s recovery. Additionally, the present case underscores the need for vigilance in identifying atypical infections and potential immunological dysregulation in postoperative patients. Further research is essential to refine prevention and management approaches for rare and challenging infections.\n                    <\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE24891\">https:\/\/thejns.org\/doi\/10.3171\/CASE24891<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case24891","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T20:14:22Z","timestamp":1745871262000},"source":"Crossref","is-referenced-by-count":2,"title":["Mycobacterium abscessus infection of uncertain etiology following lumbar spine decompression and instrumentation: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"given":"Sloan V.","family":"Rhodes","sequence":"first","affiliation":[{"name":"College of Medicine, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noah L. A.","family":"Nawabi","sequence":"additional","affiliation":[{"name":"College of Medicine, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian F.","family":"Saway","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Triano","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay K.","family":"Varma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"3","key":"bib1","series-title":"Transpl Infect Dis","first-page":"418","article-title":"Mycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review","volume":"17","author":"Silva","year":"2015","unstructured":"Silva JTL\u00f3pez-Medrano FFern\u00e1ndez-Ruiz MMycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review. Transpl Infect Dis. 2015;17(3):418-423."},{"issue":"6","key":"bib2","series-title":"Infection","first-page":"1557","article-title":"Surgical site infections by atypical mycobacteria: prevalence and species characterization using MALDI-TOF and molecular LCD chip array","volume":"50","author":"Gad","year":"2022","unstructured":"Gad MAKhairat SMSalama AMAAbd Elmoez OASoliman NS.Surgical site infections by atypical mycobacteria: prevalence and species characterization using MALDI-TOF and molecular LCD chip array. Infection. 2022;50(6):1557-1563."},{"issue":"6","key":"bib3","series-title":"J Surg Case Rep","first-page":"rjy141","article-title":"Disseminated Mycobacterium abscessus infection with spondylodiscitis of thoracic spine","volume":"2018","author":"Zhang","year":"2018","unstructured":"Zhang ZSu WYOwler PBK.Disseminated Mycobacterium abscessus infection with spondylodiscitis of thoracic spine. J Surg Case Rep. 2018;2018(6):rjy141."},{"issue":"211","key":"bib4","series-title":"JNMA J Nepal Med Assoc","first-page":"696","article-title":"Surgical site infections due to non-tuberculous mycobacteria","volume":"56","author":"Yadav","year":"2018","unstructured":"Yadav RPBaskota BRanjitkar RRDahal S.Surgical site infections due to non-tuberculous mycobacteria. JNMA J Nepal Med Assoc. 2018;56(211):696-700."},{"issue":"10","key":"bib5","series-title":"Expert Rev Anti Infect Ther","first-page":"835","article-title":"Emerging and alternative strategies for the treatment of nontuberculous mycobacterial infections","volume":"22","author":"Sreekumar","year":"2024","unstructured":"Sreekumar AKumar ABiswas RBiswas L.Emerging and alternative strategies for the treatment of nontuberculous mycobacterial infections. Expert Rev Anti Infect Ther. 2024;22(10):835-853."},{"issue":"3","key":"bib1","series-title":"Transpl Infect Dis","first-page":"418","article-title":"Mycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review","volume":"17","author":"Silva","year":"2015","unstructured":"Silva JTL\u00f3pez-Medrano FFern\u00e1ndez-Ruiz MMycobacterium abscessus pulmonary infection complicated with vertebral osteomyelitis in a heart transplant recipient: case report and literature review. Transpl Infect Dis. 2015;17(3):418-423."},{"issue":"6","key":"bib2","series-title":"Infection","first-page":"1557","article-title":"Surgical site infections by atypical mycobacteria: prevalence and species characterization using MALDI-TOF and molecular LCD chip array","volume":"50","author":"Gad","year":"2022","unstructured":"Gad MAKhairat SMSalama AMAAbd Elmoez OASoliman NS.Surgical site infections by atypical mycobacteria: prevalence and species characterization using MALDI-TOF and molecular LCD chip array. Infection. 2022;50(6):1557-1563."},{"issue":"6","key":"bib3","series-title":"J Surg Case Rep","first-page":"rjy141","article-title":"Disseminated Mycobacterium abscessus infection with spondylodiscitis of thoracic spine","volume":"2018","author":"Zhang","year":"2018","unstructured":"Zhang ZSu WYOwler PBK.Disseminated Mycobacterium abscessus infection with spondylodiscitis of thoracic spine. J Surg Case Rep. 2018;2018(6):rjy141."},{"issue":"211","key":"bib4","series-title":"JNMA J Nepal Med Assoc","first-page":"696","article-title":"Surgical site infections due to non-tuberculous mycobacteria","volume":"56","author":"Yadav","year":"2018","unstructured":"Yadav RPBaskota BRanjitkar RRDahal S.Surgical site infections due to non-tuberculous mycobacteria. JNMA J Nepal Med Assoc. 2018;56(211):696-700."},{"issue":"10","key":"bib5","series-title":"Expert Rev Anti Infect Ther","first-page":"835","article-title":"Emerging and alternative strategies for the treatment of nontuberculous mycobacterial infections","volume":"22","author":"Sreekumar","year":"2024","unstructured":"Sreekumar AKumar ABiswas RBiswas L.Emerging and alternative strategies for the treatment of nontuberculous mycobacterial infections. Expert Rev Anti Infect Ther. 2024;22(10):835-853."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/17\/article-CASE24891.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/17\/article-CASE24891.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/17\/article-CASE24891.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:38:17Z","timestamp":1770075497000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/17\/article-CASE24891.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,28]]},"references-count":10,"journal-issue":{"issue":"17"},"URL":"https:\/\/doi.org\/10.3171\/case24891","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,28]]}}}