{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:31:45Z","timestamp":1770114705474,"version":"3.49.0"},"reference-count":52,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"24","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,6,16]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Trigeminal neuralgia (TN) is a disorder of chronic facial pain and can be treated by radiofrequency ablation (RFA) rhizotomy of the trigeminal nerve. The use of robotic systems like the Globus ExcelsiusGPS may enhance precision and safety in intracranial procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 58-year-old male with a history of TN unresponsive to multiple treatments, including microvascular decompression (MVD) and Gamma Knife radiosurgery, underwent robot-assisted RFA rhizotomy. The Globus ExcelsiusGPS robot was used to guide a needle precisely to the gasserian ganglion through the foramen ovale. The needle\u2019s trajectory was confirmed via intraoperative CT, and RFA was performed at 70\u00b0C for 90 seconds. The procedure was well tolerated with no complications. The patient reported immediate improvement in left-sided facial pain postoperatively and was discharged the following day. At the 2-week follow-up, the patient showed resolution of preoperative symptoms. The successful implementation of robot-assisted RFA rhizotomy using the Globus ExcelsiusGPS robot for TN resulted in significant pain relief and minimal complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>This report demonstrates the potential of robot-assisted RFA in improving surgical precision, control, and patient outcomes in TN treatment. Further investigation into the long-term efficacy and safety of this innovative approach is warranted to fully understand its benefits and accuracy.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE2510\">https:\/\/thejns.org\/doi\/10.3171\/CASE2510<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case2510","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T20:02:18Z","timestamp":1750104138000},"source":"Crossref","is-referenced-by-count":0,"title":["Robot-assisted trigeminal nerve rhizotomy with radiofrequency ablation using Globus ExcelsiusGPS: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"given":"Joseph","family":"Rajasekaran","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Drexel University College of Medicine, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajan","family":"Thakore","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Northwestern University, Evanston, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohaid","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hael","family":"Abdulrazeq","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5735-2654","authenticated-orcid":true,"given":"Carlin","family":"Chuck","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deus","family":"Cielo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clark C.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"Sampath","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"bib1","series-title":"BMJ","first-page":"h1238","article-title":"Trigeminal neuralgia","volume":"350","author":"Zakrzewska","year":"2015","unstructured":"Zakrzewska JMLinskey ME.Trigeminal neuralgia. BMJ. 2015;350:h1238."},{"issue":"7","key":"bib2","series-title":"J Am Dent Assoc","first-page":"570","article-title":"Prevalence of trigeminal neuralgia: a systematic review","volume":"147","author":"De Toledo","year":"2016","unstructured":"De Toledo IPConti R\u00e9us JFernandes MPrevalence of trigeminal neuralgia: a systematic review. J Am Dent Assoc. 2016;147(7):570-576.e2."},{"issue":"suppl 2","key":"bib3","series-title":"Neurol Sci","first-page":"s65","article-title":"Epidemiology of typical and atypical craniofacial neuralgias","volume":"26","author":"Manzoni","year":"2005","unstructured":"Manzoni GCTorelli P.Epidemiology of typical and atypical craniofacial neuralgias. Neurol Sci. 2005;26(suppl 2):s65-s67."},{"issue":"3","key":"bib4","series-title":"Expert Rev Neurother","first-page":"323","article-title":"Update on trigeminal neuralgia","volume":"9","author":"Obermann","year":"2009","unstructured":"Obermann MKatsarava Z.Update on trigeminal neuralgia. Expert Rev Neurother. 2009;9(3):323-329."},{"issue":"7","key":"bib5","series-title":"Cephalalgia","first-page":"648","article-title":"Trigeminal neuralgia\u2014diagnosis and treatment","volume":"37","author":"Maarbjerg","year":"2017","unstructured":"Maarbjerg SDi Stefano GBendtsen LCruccu G.Trigeminal neuralgia\u2014diagnosis and treatment. Cephalalgia. 2017;37(7):648-657."},{"issue":"12","key":"bib6","series-title":"Brain","first-page":"2347","article-title":"Trigeminal neuralgia: pathology and pathogenesis","volume":"124","author":"Love","year":"2001","unstructured":"Love SCoakham HB.Trigeminal neuralgia: pathology and pathogenesis. Brain. 2001;124(12):2347-2360."},{"issue":"3","key":"bib7","series-title":"J Neurol Neurosurg Psychiatry","first-page":"253","article-title":"Association between trigeminal neuralgia and multiple sclerosis: role of magnetic resonance imaging","volume":"59","author":"Meaney","year":"1995","unstructured":"Meaney JFWatt JWEldridge PRWhitehouse GHWells JCMiles JB.Association between trigeminal neuralgia and multiple sclerosis: role of magnetic resonance imaging. J Neurol Neurosurg Psychiatry. 1995;59(3):253-259."},{"issue":"5","key":"bib8","series-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod","first-page":"527","article-title":"Trigeminal neuralgia","volume":"100","author":"Scrivani","year":"2005","unstructured":"Scrivani SJMathews ESMaciewicz RJ.Trigeminal neuralgia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(5):527-538."},{"issue":"6","key":"bib9","series-title":"J Neurosurg","first-page":"1144","article-title":"Microvascular decompression for primary trigeminal neuralgia: long-term effectiveness and prognostic factors in a series of 362 consecutive patients with clear-cut neurovascular conflicts who underwent pure decompression","volume":"107","author":"Sindou","year":"2007","unstructured":"Sindou MLeston JDecullier EChapuis F.Microvascular decompression for primary trigeminal neuralgia: long-term effectiveness and prognostic factors in a series of 362 consecutive patients with clear-cut neurovascular conflicts who underwent pure decompression. 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In: Proceedings of the 14th Hamlyn Symposium on Medical Robotics 2022. The Hamlyn Centre Imperial College London; 2022:159-160."},{"issue":"3","key":"bib18","series-title":"HSS J","first-page":"302","article-title":"Workflow and efficiency of robotic-assisted navigation in spine surgery","volume":"17","author":"Avrumova","year":"2021","unstructured":"Avrumova FSivaganesan AAlluri RKVaishnav AQureshi SLebl DR.Workflow and efficiency of robotic-assisted navigation in spine surgery. HSS J. 2021;17(3):302-307."},{"issue":"5","key":"bib19","series-title":"Int J Spine Surg","first-page":"459","article-title":"Initial single-institution experience with a novel robotic-navigation system for thoracolumbar pedicle screw and pelvic screw placement with 643 screws","volume":"13","author":"JAIN","year":"2019","unstructured":"JAIN DMANNING JLORD EInitial single-institution experience with a novel robotic-navigation system for thoracolumbar pedicle screw and pelvic screw placement with 643 screws. 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Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(5):527-538."},{"issue":"6","key":"bib9","series-title":"J Neurosurg","first-page":"1144","article-title":"Microvascular decompression for primary trigeminal neuralgia: long-term effectiveness and prognostic factors in a series of 362 consecutive patients with clear-cut neurovascular conflicts who underwent pure decompression","volume":"107","author":"Sindou","year":"2007","unstructured":"Sindou MLeston JDecullier EChapuis F.Microvascular decompression for primary trigeminal neuralgia: long-term effectiveness and prognostic factors in a series of 362 consecutive patients with clear-cut neurovascular conflicts who underwent pure decompression. 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