{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:30:12Z","timestamp":1769725812984,"version":"3.49.0"},"reference-count":40,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","license":[{"start":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T00:00:00Z","timestamp":1753660800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,7,28]]},"abstract":"\n BACKGROUND<\/jats:title>\n Neurenteric cysts (NECs) can form anywhere along the neuroaxis.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n Thirteen patients with NECs were treated at a single institution: 7 with intraspinal lesions and 6 with cranial lesions. Spinal cysts presented with pain (28.6%), scoliosis (42.9%), gait changes (28.6%), and progressive weakness (14.3%). Infratentorial cysts (n = 4) presented with headache and neck pain; the CN III cyst (n = 1) presented with CN III palsy, headaches, and facial pain; and the convexity NEC (n = 1) presented with seizures. Complete resection was achieved without recurrence for all spinal and infratentorial NECs. Both supratentorial NECs had radiographic recurrence within 1 year of surgery, one of which recurred after gross-total resection. The CN III NEC did not require reintervention with durable improvement in pain, headaches, and CN III function postoperatively. Convexity recurrence was associated with recurrent seizures; complete re-resection was achieved with durable improvement in seizures. No perioperative complications were associated with supratentorial, infratentorial, or sacral NECs. All complications were associated with ventral thoracic NECs and included a CSF leak (n = 1), neurological worsening (n = 1), and symptomatic delayed tethering (n = 2).<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n NECs can occur anywhere within the neuroaxis. Symptomatic cysts require treatment. The cyst location impacts the surgical approach and can inform discussions regarding the operative risk and anticipated outcomes for patients and their families.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE25165<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case25165","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T06:32:32Z","timestamp":1753684352000},"source":"Crossref","is-referenced-by-count":0,"title":["Characteristics and management of neurenteric cysts in the pediatric population: patient series"],"prefix":"10.3171","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1764-7134","authenticated-orcid":true,"given":"Amanda M.","family":"Mosher","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0431-3045","authenticated-orcid":true,"given":"Marcella","family":"Ruppert-Gomez","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6131-2230","authenticated-orcid":true,"given":"John S.","family":"Albanese","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3058-3513","authenticated-orcid":true,"given":"Joanna E.","family":"Papadakis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8115-7409","authenticated-orcid":true,"given":"Carolina","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Proctor","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie P.","family":"Fehnel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"},{"name":"Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"923","key":"bib1","series-title":"Br J Radiol","first-page":"963","article-title":"Intracranial laterally based supratentorial neurenteric cyst","volume":"77","author":"Tan","year":"2004","unstructured":"Tan GSHortob\u00e1gyi TAl-Sarraj SConnor SEJ.Intracranial laterally based supratentorial neurenteric cyst. Br J Radiol. 2004;77(923):963-965."},{"issue":"2","key":"bib2","series-title":"Clin Neurol Neurosurg","first-page":"89","article-title":"Supratentorial neurenteric cysts\u2014a fascinating entity of uncertain embryopathogenesis","volume":"112","author":"Mittal","year":"2010","unstructured":"Mittal SPetrecca KSabbagh AJSupratentorial neurenteric cysts\u2014a fascinating entity of uncertain embryopathogenesis. Clin Neurol Neurosurg. 2010;112(2):89-97."},{"issue":"6","key":"bib3","series-title":"AJNR Am J Neuroradiol","first-page":"1211","article-title":"Intracranial neurenteric cysts: imaging and pathology spectrum","volume":"27","author":"Preece","year":"2006","unstructured":"Preece MTOsborn AGChin SSSmirniotopoulos JG.Intracranial neurenteric cysts: imaging and pathology spectrum. AJNR Am J Neuroradiol. 2006;27(6):1211-1216."},{"issue":"1","key":"bib4","series-title":"J Craniovertebr Junction Spine","first-page":"58","article-title":"Neurenteric cysts of the spine","volume":"1","author":"Savage","year":"2010","unstructured":"Savage JJCasey JNMcNeill ITSherman JH.Neurenteric cysts of the spine. J Craniovertebr Junction Spine. 2010;1(1):58-63."},{"issue":"6","key":"bib5","series-title":"Pediatr Neurosurg","first-page":"284","article-title":"Spinal neurenteric cyst. Report of 4 cases and review of the literature","volume":"40","author":"Shenoy","year":"2004","unstructured":"Shenoy SNRaja A.Spinal neurenteric cyst. Report of 4 cases and review of the literature. Pediatr Neurosurg. 2004;40(6):284-292."},{"issue":"10","key":"bib6","series-title":"Childs Nerv Syst","first-page":"584","article-title":"Intraspinal neurenteric cysts\u2014report of three paediatric cases","volume":"17","author":"Kumar","year":"2001","unstructured":"Kumar RJain RRao KMHussain N.Intraspinal neurenteric cysts\u2014report of three paediatric cases. Childs Nerv Syst. 2001;17(10):584-588."},{"issue":"1","key":"bib7","series-title":"Neurosurg Focus","first-page":"e2","article-title":"Spinal neurenteric cysts and their relation to more common aspects of occult spinal dysraphism","volume":"10","author":"Rauzzino","year":"2001","unstructured":"Rauzzino MJTubbs RSAlexander EGrabb PAOakes WJ.Spinal neurenteric cysts and their relation to more common aspects of occult spinal dysraphism. Neurosurg Focus. 2001;10(1):e2."},{"issue":"3","key":"bib8","series-title":"Br J Neurosurg","first-page":"185","article-title":"Spinal neurenteric cysts without associated malformations. Are they the same as those presenting in spinal dysraphism?","volume":"14","author":"Paleologos","year":"2000","unstructured":"Paleologos TSThom MThomas DG.Spinal neurenteric cysts without associated malformations. Are they the same as those presenting in spinal dysraphism? Br J Neurosurg. 2000;14(3):185-194."},{"issue":"6","key":"bib9","series-title":"J Neurosurg","first-page":"512","article-title":"Neurenteric cysts in children: 16 consecutive cases and review of the literature","volume":"103","author":"de Oliveira de","year":"2005","unstructured":"de Oliveira de RSCinalli GRoujeau TSainte-Rose CPierre-Kahn AZerah M.Neurenteric cysts in children: 16 consecutive cases and review of the literature. J Neurosurg. 2005;103(6)(suppl):512-523."},{"issue":"12","key":"bib10","series-title":"Childs Nerv Syst","first-page":"3681","article-title":"Pediatric intracranial neurenteric cyst of the oculomotor nerve: a case-based review","volume":"37","author":"Oppenhuizen","year":"2021","unstructured":"Oppenhuizen BRagheb JLeuchter JDClarke JEPelaez LWang S.Pediatric intracranial neurenteric cyst of the oculomotor nerve: a case-based review. Childs Nerv Syst. 2021;37(12):3681-3693."},{"issue":"2","key":"bib11","series-title":"J Neurosurg","first-page":"326","article-title":"Endodermal cysts of the posterior fossa: report of three cases and review of the literature","volume":"89","author":"Bejjani","year":"1998","unstructured":"Bejjani GKWright DCSchessel DSekhar LN.Endodermal cysts of the posterior fossa: report of three cases and review of the literature. J Neurosurg. 1998;89(2):326-335."},{"issue":"1","key":"bib12","series-title":"J Neurosurg Pediatr","first-page":"45","article-title":"Primary nerve repair following resection of a neurenteric cyst of the oculomotor nerve","volume":"9","author":"Turner","year":"2012","unstructured":"Turner SJDexter MASmith JEHOuvrier R.Primary nerve repair following resection of a neurenteric cyst of the oculomotor nerve. J Neurosurg Pediatr. 2012;9(1):45-48."},{"issue":"3","key":"bib13","series-title":"J Pediatr Ophthalmol Strabismus","first-page":"176","article-title":"Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie\u2019s tonic pupil","volume":"42","author":"Werner","year":"2005","unstructured":"Werner MBhatti MTVaishnav HPincus DWEskin TYachnis AT.Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie\u2019s tonic pupil. J Pediatr Ophthalmol Strabismus. 2005;42(3):176-179."},{"issue":"4","key":"bib14","series-title":"Childs Nerv Syst","first-page":"639","article-title":"Neurenteric cyst: an unusual cause of third nerve palsy","volume":"27","author":"Wait","year":"2011","unstructured":"Wait SDChoi LSJTeo C.Neurenteric cyst: an unusual cause of third nerve palsy. Childs Nerv Syst. 2011;27(4):639-641."},{"issue":"1","key":"bib15","series-title":"Br J Neurosurg","first-page":"105","article-title":"Clinical and radiological features of endodermal cyst in the oculomotor nerve: a case report","volume":"29","author":"Tanaka","year":"2015","unstructured":"Tanaka MFujimoto YHirayama RChiba YHashimoto NYoshimine T.Clinical and radiological features of endodermal cyst in the oculomotor nerve: a case report. Br J Neurosurg. 2015;29(1):105-106."},{"issue":"5","key":"bib16","series-title":"Neurosurgery","article-title":"Endodermal cyst of the oculomotor nerve: case report","volume":"58","author":"Okunaga","year":"2006","unstructured":"Okunaga TTsutsumi KHayashi TNagata I.Endodermal cyst of the oculomotor nerve: case report. Neurosurgery. 2006;58(5):E994."},{"issue":"12","key":"bib17","series-title":"Neuroradiology","first-page":"1063","article-title":"Endodermal cyst of the oculomotor nerve","volume":"43","author":"Morgan","year":"2001","unstructured":"Morgan MAEnterline DSFukushima TMcLendon RECummings TJ.Endodermal cyst of the oculomotor nerve. Neuroradiology. 2001;43(12):1063-1066."},{"issue":"2","key":"bib18","series-title":"Pediatr Neurosurg","first-page":"155","article-title":"Endodermal cyst of the oculomotor nerve","volume":"46","author":"Karikari","year":"2010","unstructured":"Karikari IOGrant GCummings TJPetrella JFuchs HE.Endodermal cyst of the oculomotor nerve. Pediatr Neurosurg. 2010;46(2):155-156."},{"issue":"3","key":"bib19","series-title":"J Neuroophthalmol","first-page":"311","article-title":"Endodermal cyst of the third nerve in a child","volume":"37","author":"Jiramongkolchai","year":"2017","unstructured":"Jiramongkolchai KBhatti MTFuchs HECummings TEJiramongkolchai PEl-Dairi MA.Endodermal cyst of the third nerve in a child. J Neuroophthalmol. 2017;37(3):311-313."},{"key":"bib20","series-title":"World Neurosurg","first-page":"288","article-title":"Endodermal cyst arising from the oculomotor nerve: a case report outlining the novel insertion of cysto-subarachnoid shunt for refractory disease","volume":"140","author":"Cox","year":"2020","unstructured":"Cox AAJSiedler DGAsaid MThani NB.Endodermal cyst arising from the oculomotor nerve: a case report outlining the novel insertion of cysto-subarachnoid shunt for refractory disease. World Neurosurg. 2020;140:288-292."},{"issue":"923","key":"bib1","series-title":"Br J Radiol","first-page":"963","article-title":"Intracranial laterally based supratentorial neurenteric cyst","volume":"77","author":"Tan","year":"2004","unstructured":"Tan GSHortob\u00e1gyi TAl-Sarraj SConnor SEJ.Intracranial laterally based supratentorial neurenteric cyst. Br J Radiol. 2004;77(923):963-965."},{"issue":"2","key":"bib2","series-title":"Clin Neurol Neurosurg","first-page":"89","article-title":"Supratentorial neurenteric cysts\u2014a fascinating entity of uncertain embryopathogenesis","volume":"112","author":"Mittal","year":"2010","unstructured":"Mittal SPetrecca KSabbagh AJSupratentorial neurenteric cysts\u2014a fascinating entity of uncertain embryopathogenesis. Clin Neurol Neurosurg. 2010;112(2):89-97."},{"issue":"6","key":"bib3","series-title":"AJNR Am J Neuroradiol","first-page":"1211","article-title":"Intracranial neurenteric cysts: imaging and pathology spectrum","volume":"27","author":"Preece","year":"2006","unstructured":"Preece MTOsborn AGChin SSSmirniotopoulos JG.Intracranial neurenteric cysts: imaging and pathology spectrum. AJNR Am J Neuroradiol. 2006;27(6):1211-1216."},{"issue":"1","key":"bib4","series-title":"J Craniovertebr Junction Spine","first-page":"58","article-title":"Neurenteric cysts of the spine","volume":"1","author":"Savage","year":"2010","unstructured":"Savage JJCasey JNMcNeill ITSherman JH.Neurenteric cysts of the spine. J Craniovertebr Junction Spine. 2010;1(1):58-63."},{"issue":"6","key":"bib5","series-title":"Pediatr Neurosurg","first-page":"284","article-title":"Spinal neurenteric cyst. Report of 4 cases and review of the literature","volume":"40","author":"Shenoy","year":"2004","unstructured":"Shenoy SNRaja A.Spinal neurenteric cyst. Report of 4 cases and review of the literature. Pediatr Neurosurg. 2004;40(6):284-292."},{"issue":"10","key":"bib6","series-title":"Childs Nerv Syst","first-page":"584","article-title":"Intraspinal neurenteric cysts\u2014report of three paediatric cases","volume":"17","author":"Kumar","year":"2001","unstructured":"Kumar RJain RRao KMHussain N.Intraspinal neurenteric cysts\u2014report of three paediatric cases. Childs Nerv Syst. 2001;17(10):584-588."},{"issue":"1","key":"bib7","series-title":"Neurosurg Focus","first-page":"e2","article-title":"Spinal neurenteric cysts and their relation to more common aspects of occult spinal dysraphism","volume":"10","author":"Rauzzino","year":"2001","unstructured":"Rauzzino MJTubbs RSAlexander EGrabb PAOakes WJ.Spinal neurenteric cysts and their relation to more common aspects of occult spinal dysraphism. Neurosurg Focus. 2001;10(1):e2."},{"issue":"3","key":"bib8","series-title":"Br J Neurosurg","first-page":"185","article-title":"Spinal neurenteric cysts without associated malformations. Are they the same as those presenting in spinal dysraphism?","volume":"14","author":"Paleologos","year":"2000","unstructured":"Paleologos TSThom MThomas DG.Spinal neurenteric cysts without associated malformations. Are they the same as those presenting in spinal dysraphism? Br J Neurosurg. 2000;14(3):185-194."},{"issue":"6","key":"bib9","series-title":"J Neurosurg","first-page":"512","article-title":"Neurenteric cysts in children: 16 consecutive cases and review of the literature","volume":"103","author":"de Oliveira de","year":"2005","unstructured":"de Oliveira de RSCinalli GRoujeau TSainte-Rose CPierre-Kahn AZerah M.Neurenteric cysts in children: 16 consecutive cases and review of the literature. J Neurosurg. 2005;103(6)(suppl):512-523."},{"issue":"12","key":"bib10","series-title":"Childs Nerv Syst","first-page":"3681","article-title":"Pediatric intracranial neurenteric cyst of the oculomotor nerve: a case-based review","volume":"37","author":"Oppenhuizen","year":"2021","unstructured":"Oppenhuizen BRagheb JLeuchter JDClarke JEPelaez LWang S.Pediatric intracranial neurenteric cyst of the oculomotor nerve: a case-based review. Childs Nerv Syst. 2021;37(12):3681-3693."},{"issue":"2","key":"bib11","series-title":"J Neurosurg","first-page":"326","article-title":"Endodermal cysts of the posterior fossa: report of three cases and review of the literature","volume":"89","author":"Bejjani","year":"1998","unstructured":"Bejjani GKWright DCSchessel DSekhar LN.Endodermal cysts of the posterior fossa: report of three cases and review of the literature. J Neurosurg. 1998;89(2):326-335."},{"issue":"1","key":"bib12","series-title":"J Neurosurg Pediatr","first-page":"45","article-title":"Primary nerve repair following resection of a neurenteric cyst of the oculomotor nerve","volume":"9","author":"Turner","year":"2012","unstructured":"Turner SJDexter MASmith JEHOuvrier R.Primary nerve repair following resection of a neurenteric cyst of the oculomotor nerve. J Neurosurg Pediatr. 2012;9(1):45-48."},{"issue":"3","key":"bib13","series-title":"J Pediatr Ophthalmol Strabismus","first-page":"176","article-title":"Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie\u2019s tonic pupil","volume":"42","author":"Werner","year":"2005","unstructured":"Werner MBhatti MTVaishnav HPincus DWEskin TYachnis AT.Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie\u2019s tonic pupil. J Pediatr Ophthalmol Strabismus. 2005;42(3):176-179."},{"issue":"4","key":"bib14","series-title":"Childs Nerv Syst","first-page":"639","article-title":"Neurenteric cyst: an unusual cause of third nerve palsy","volume":"27","author":"Wait","year":"2011","unstructured":"Wait SDChoi LSJTeo C.Neurenteric cyst: an unusual cause of third nerve palsy. Childs Nerv Syst. 2011;27(4):639-641."},{"issue":"1","key":"bib15","series-title":"Br J Neurosurg","first-page":"105","article-title":"Clinical and radiological features of endodermal cyst in the oculomotor nerve: a case report","volume":"29","author":"Tanaka","year":"2015","unstructured":"Tanaka MFujimoto YHirayama RChiba YHashimoto NYoshimine T.Clinical and radiological features of endodermal cyst in the oculomotor nerve: a case report. Br J Neurosurg. 2015;29(1):105-106."},{"issue":"5","key":"bib16","series-title":"Neurosurgery","article-title":"Endodermal cyst of the oculomotor nerve: case report","volume":"58","author":"Okunaga","year":"2006","unstructured":"Okunaga TTsutsumi KHayashi TNagata I.Endodermal cyst of the oculomotor nerve: case report. Neurosurgery. 2006;58(5):E994."},{"issue":"12","key":"bib17","series-title":"Neuroradiology","first-page":"1063","article-title":"Endodermal cyst of the oculomotor nerve","volume":"43","author":"Morgan","year":"2001","unstructured":"Morgan MAEnterline DSFukushima TMcLendon RECummings TJ.Endodermal cyst of the oculomotor nerve. Neuroradiology. 2001;43(12):1063-1066."},{"issue":"2","key":"bib18","series-title":"Pediatr Neurosurg","first-page":"155","article-title":"Endodermal cyst of the oculomotor nerve","volume":"46","author":"Karikari","year":"2010","unstructured":"Karikari IOGrant GCummings TJPetrella JFuchs HE.Endodermal cyst of the oculomotor nerve. Pediatr Neurosurg. 2010;46(2):155-156."},{"issue":"3","key":"bib19","series-title":"J Neuroophthalmol","first-page":"311","article-title":"Endodermal cyst of the third nerve in a child","volume":"37","author":"Jiramongkolchai","year":"2017","unstructured":"Jiramongkolchai KBhatti MTFuchs HECummings TEJiramongkolchai PEl-Dairi MA.Endodermal cyst of the third nerve in a child. J Neuroophthalmol. 2017;37(3):311-313."},{"key":"bib20","series-title":"World Neurosurg","first-page":"288","article-title":"Endodermal cyst arising from the oculomotor nerve: a case report outlining the novel insertion of cysto-subarachnoid shunt for refractory disease","volume":"140","author":"Cox","year":"2020","unstructured":"Cox AAJSiedler DGAsaid MThani NB.Endodermal cyst arising from the oculomotor nerve: a case report outlining the novel insertion of cysto-subarachnoid shunt for refractory disease. World Neurosurg. 2020;140:288-292."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/10\/4\/article-CASE25165.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/10\/4\/article-CASE25165.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/10\/4\/article-CASE25165.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T11:11:05Z","timestamp":1769685065000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/10\/4\/article-CASE25165.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":40,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/case25165","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]}}}