{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T15:11:00Z","timestamp":1783177860190,"version":"3.54.6"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"25","license":[{"start":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T00:00:00Z","timestamp":1750636800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,6,23]]},"abstract":"\n BACKGROUND<\/jats:title>\n Central hypoventilation syndrome due to unilateral cerebellomedullary infarction is rare and difficult to manage using conventional treatment. Diaphragm pacing can support ventilation in patients with hypoventilation syndrome, mainly because of the high risk of cervical injury. There have been few reports of diaphragm pacing for central hypoventilation syndrome due to unilateral cerebellomedullary infarction.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n A 77-year-old man presented with dizziness, truncal ataxia, and dysarthria. MRI showed cerebral infarction in the right lateral medulla oblongata and right cerebellar hemisphere. The patient presented with respiratory failure immediately after admission. The patient required mechanical ventilation and tracheostomy support. Spontaneous breathing was insufficient, particularly during sleep. After a 2-month interval, the ventilator-dependent patient underwent diaphragm pacing. He was weaned from the ventilator 13 days after diaphragm pacing.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n The authors reported successful treatment with diaphragm pacing for central hypoventilation syndrome due to unilateral cerebellomedullary infarction. Diaphragm pacing is a good treatment option for patients with central hypoventilation syndrome.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE25172<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case25172","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T20:03:29Z","timestamp":1751313809000},"source":"Crossref","is-referenced-by-count":1,"title":["Diaphragm pacing for central hypoventilation syndrome due to unilateral cerebellomedullary infarction: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6376-6980","authenticated-orcid":true,"given":"Hiroki","family":"Kobayashi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jouji","family":"Kokuzawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Kaku","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Asahi University Hospital, Gifu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"5","key":"bib1","series-title":"Ann Neurol","first-page":"668","article-title":"Respiratory failure and unilateral caudal brainstem infarction","volume":"28","author":"Bogousslavsky","year":"1990","unstructured":"Bogousslavsky JKhurana RDeruaz JPRespiratory failure and unilateral caudal brainstem infarction. Ann Neurol. 1990;28(5):668-673."},{"issue":"8","key":"bib2","series-title":"Arch Neurol","first-page":"1286","article-title":"Paroxysmal apnea and vasomotor instability following medullary infarction","volume":"62","author":"Lassman","year":"2005","unstructured":"Lassman ABMayer SA.Paroxysmal apnea and vasomotor instability following medullary infarction. Arch Neurol. 2005;62(8):1286-1288."},{"issue":"1","key":"bib3","series-title":"J Stroke Cerebrovasc Dis","first-page":"41","article-title":"Rapidly progressive fatal respiratory failure (Ondine's curse) in the lateral medullary syndrome","volume":"13","author":"Terao","year":"2004","unstructured":"Terao SMiura NOsano YNoda ASobue G.Rapidly progressive fatal respiratory failure (Ondine's curse) in the lateral medullary syndrome. J Stroke Cerebrovasc Dis. 2004;13(1):41-44."},{"issue":"14","key":"bib4","series-title":"Neurology","first-page":"e1557","article-title":"Teaching NeuroImages: Ondine curse syndrome caused by dorsolateral medullary stroke","volume":"94","author":"Fiedler","year":"2020","unstructured":"Fiedler EGill R.Teaching NeuroImages: Ondine curse syndrome caused by dorsolateral medullary stroke. Neurology. 2020;94(14):e1557-e1558."},{"issue":"24","key":"bib5","series-title":"Neurology","first-page":"2140","article-title":"Brainstem respiratory chemosensitivity: new insights and clinical implications","volume":"68","author":"Benarroch","year":"2007","unstructured":"Benarroch EE.Brainstem respiratory chemosensitivity: new insights and clinical implications. Neurology. June 12 2007;68(24):2140-2143."},{"issue":"2","key":"bib6","series-title":"Eur Neurol","first-page":"70","article-title":"Acute respiratory failure due to unilateral dorsolateral bulbar infarction","volume":"66","author":"Kumral","year":"2011","unstructured":"Kumral EUzunk\u00f6pr\u00fc C\u00c7ift\u00e7i SDemirci T.Acute respiratory failure due to unilateral dorsolateral bulbar infarction. Eur Neurol. 2011;66(2):70-74."},{"issue":"4","key":"bib7","series-title":"J Nippon Med Sch","first-page":"276","article-title":"Efficacy of tracheostomy for central alveolar hypoventilation syndrome caused by lateral medullary infarction","volume":"81","author":"Mishina","year":"2014","unstructured":"Mishina MOhkubo SKamiya NEfficacy of tracheostomy for central alveolar hypoventilation syndrome caused by lateral medullary infarction. J Nippon Med Sch. 2014;81(4):276-284."},{"issue":"10","key":"bib8","series-title":"Artif Organs","first-page":"1980","article-title":"Diaphragm pacing in spinal cord injury can significantly decrease mechanical ventilation in multicenter prospective evaluation","volume":"46","author":"Onders","year":"2022","unstructured":"Onders RPKhansarinia SIngvarsson PEDiaphragm pacing in spinal cord injury can significantly decrease mechanical ventilation in multicenter prospective evaluation. Artif Organs. 2022;46(10):1980-1987."},{"issue":"115","key":"bib9","series-title":"Issues Emerg Health Technol","first-page":"1","article-title":"Laparoscopic diaphragm pacing for tetraplegia","author":"Dibidino","year":"2009","unstructured":"Dibidino RMorrison A.Laparoscopic diaphragm pacing for tetraplegia. Issues Emerg Health Technol. 2009;(115):1-5."},{"issue":"2","key":"bib10","series-title":"J Trauma Acute Care Surg","first-page":"303","article-title":"Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration","volume":"76","author":"Posluszny","year":"2014","unstructured":"Posluszny JAJrOnders RKerwin AJMulticenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration. J Trauma Acute Care Surg. 2014;76(2):303-310."},{"issue":"5","key":"bib1","series-title":"Ann Neurol","first-page":"668","article-title":"Respiratory failure and unilateral caudal brainstem infarction","volume":"28","author":"Bogousslavsky","year":"1990","unstructured":"Bogousslavsky JKhurana RDeruaz JPRespiratory failure and unilateral caudal brainstem infarction. Ann Neurol. 1990;28(5):668-673."},{"issue":"8","key":"bib2","series-title":"Arch Neurol","first-page":"1286","article-title":"Paroxysmal apnea and vasomotor instability following medullary infarction","volume":"62","author":"Lassman","year":"2005","unstructured":"Lassman ABMayer SA.Paroxysmal apnea and vasomotor instability following medullary infarction. Arch Neurol. 2005;62(8):1286-1288."},{"issue":"1","key":"bib3","series-title":"J Stroke Cerebrovasc Dis","first-page":"41","article-title":"Rapidly progressive fatal respiratory failure (Ondine's curse) in the lateral medullary syndrome","volume":"13","author":"Terao","year":"2004","unstructured":"Terao SMiura NOsano YNoda ASobue G.Rapidly progressive fatal respiratory failure (Ondine's curse) in the lateral medullary syndrome. J Stroke Cerebrovasc Dis. 2004;13(1):41-44."},{"issue":"14","key":"bib4","series-title":"Neurology","first-page":"e1557","article-title":"Teaching NeuroImages: Ondine curse syndrome caused by dorsolateral medullary stroke","volume":"94","author":"Fiedler","year":"2020","unstructured":"Fiedler EGill R.Teaching NeuroImages: Ondine curse syndrome caused by dorsolateral medullary stroke. Neurology. 2020;94(14):e1557-e1558."},{"issue":"24","key":"bib5","series-title":"Neurology","first-page":"2140","article-title":"Brainstem respiratory chemosensitivity: new insights and clinical implications","volume":"68","author":"Benarroch","year":"2007","unstructured":"Benarroch EE.Brainstem respiratory chemosensitivity: new insights and clinical implications. Neurology. June 12 2007;68(24):2140-2143."},{"issue":"2","key":"bib6","series-title":"Eur Neurol","first-page":"70","article-title":"Acute respiratory failure due to unilateral dorsolateral bulbar infarction","volume":"66","author":"Kumral","year":"2011","unstructured":"Kumral EUzunk\u00f6pr\u00fc C\u00c7ift\u00e7i SDemirci T.Acute respiratory failure due to unilateral dorsolateral bulbar infarction. Eur Neurol. 2011;66(2):70-74."},{"issue":"4","key":"bib7","series-title":"J Nippon Med Sch","first-page":"276","article-title":"Efficacy of tracheostomy for central alveolar hypoventilation syndrome caused by lateral medullary infarction","volume":"81","author":"Mishina","year":"2014","unstructured":"Mishina MOhkubo SKamiya NEfficacy of tracheostomy for central alveolar hypoventilation syndrome caused by lateral medullary infarction. J Nippon Med Sch. 2014;81(4):276-284."},{"issue":"10","key":"bib8","series-title":"Artif Organs","first-page":"1980","article-title":"Diaphragm pacing in spinal cord injury can significantly decrease mechanical ventilation in multicenter prospective evaluation","volume":"46","author":"Onders","year":"2022","unstructured":"Onders RPKhansarinia SIngvarsson PEDiaphragm pacing in spinal cord injury can significantly decrease mechanical ventilation in multicenter prospective evaluation. Artif Organs. 2022;46(10):1980-1987."},{"issue":"115","key":"bib9","series-title":"Issues Emerg Health Technol","first-page":"1","article-title":"Laparoscopic diaphragm pacing for tetraplegia","author":"Dibidino","year":"2009","unstructured":"Dibidino RMorrison A.Laparoscopic diaphragm pacing for tetraplegia. Issues Emerg Health Technol. 2009;(115):1-5."},{"issue":"2","key":"bib10","series-title":"J Trauma Acute Care Surg","first-page":"303","article-title":"Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration","volume":"76","author":"Posluszny","year":"2014","unstructured":"Posluszny JAJrOnders RKerwin AJMulticenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration. J Trauma Acute Care Surg. 2014;76(2):303-310."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/25\/article-CASE25172.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/25\/article-CASE25172.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/25\/article-CASE25172.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:40:57Z","timestamp":1770075657000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/25\/article-CASE25172.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,23]]},"references-count":20,"journal-issue":{"issue":"25"},"URL":"https:\/\/doi.org\/10.3171\/case25172","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,23]]}}}