{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:37:08Z","timestamp":1769726228612,"version":"3.49.0"},"reference-count":52,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"25","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurosurg Case Lessons"],"published-print":{"date-parts":[[2025,12,22]]},"abstract":"\n BACKGROUND<\/jats:title>\n Myxopapillary ependymomas (MPEs) are rare intradural extramedullary tumors that often involve the conus and cauda equina. Current guidelines recommend resection as first-line management, but, despite a 92.4% overall 10-year survival rate, MPEs often have a high potential for postoperative morbidity with persisting or worsened neurological function. While several studies have identified potential radiological prognostic factors, none have specifically explored their relation to neurological outcomes.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n The authors retrospectively reviewed 16 MPE cases surgically treated within their institution between 2010 and 2021, evaluating preoperative\/postoperative clinical data, surgical variables, and preoperative radiological features. Univariable analysis was performed using ANOVA for continuous variables and the chi-square test for categorical variables across neurological outcome groups. Multivariable modeling of neurological outcomes was done using logistic regression utilizing only radiological variables with a p value < 0.2. None of the radiological predictors reached statistical significance. The presence of preoperative weakness was the only significant predictor of a good neurological outcome within this model, while conus involvement was a significant predictor of urinary dysfunction at the final follow-up.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n Tumor size, conus involvement, and preoperative weakness are prognostic factors that may affect the morbidity profile of patients following resection.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE25392<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case25392","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:00:00Z","timestamp":1769083200000},"source":"Crossref","is-referenced-by-count":0,"title":["Radiological analysis correlated with neurological outcomes following resection of myxopapillary ependymoma: patient series"],"prefix":"10.3171","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6844-675X","authenticated-orcid":true,"given":"Nitish","family":"Seenarine","sequence":"first","affiliation":[{"name":"College of Medicine, State University of New York Downstate Health Sciences University, Brooklyn, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noah M.","family":"Nichols","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mount Sinai Health System, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John K.","family":"Houten","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mount Sinai Health System, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3715-8093","authenticated-orcid":true,"given":"Konstantinos","family":"Margetis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mount Sinai Health System, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"8","key":"bib1","series-title":"Curr Oncol Rep","first-page":"985","article-title":"Ependymoma: evaluation and management updates","volume":"24","author":"Rud\u00e0","year":"2022","unstructured":"Rud\u00e0 RBruno FPellerino ASoffietti R.Ependymoma: evaluation and management updates. Curr Oncol Rep. 2022;24(8):985-993."},{"issue":"4","key":"bib2","series-title":"Glob Spine J","first-page":"1905","article-title":"Development and validation of a predictive nomogram for patients with myxopapillary ependymoma: a surveillance, epidemiology, and end results (SEER) retrospective cohort analysis","volume":"15","author":"Bhutada","year":"2025","unstructured":"Bhutada ASAdhikari SCuoco JAHoggarth ARPatel VMOlasunkanmi AL.Development and validation of a predictive nomogram for patients with myxopapillary ependymoma: a surveillance, epidemiology, and end results (SEER) retrospective cohort analysis. Glob Spine J. 2025;15(4):1905-1913."},{"issue":"2","key":"bib3","series-title":"J Neurooncol","first-page":"251","article-title":"Myxopapillary ependymoma: a SEER analysis of epidemiology and outcomes","volume":"129","author":"Bates","year":"2016","unstructured":"Bates JEChoi GMilano MT.Myxopapillary ependymoma: a SEER analysis of epidemiology and outcomes. J Neurooncol. 2016;129(2):251-258."},{"issue":"1","key":"bib4","series-title":"Spinal Cord Ser Cases","first-page":"43","article-title":"Multifocal lumbar myxopapillary ependymoma presenting with drop metastasis: a case report and review of the literature","volume":"8","author":"Tabor","year":"2022","unstructured":"Tabor JKRyu BSchneider DMultifocal lumbar myxopapillary ependymoma presenting with drop metastasis: a case report and review of the literature. Spinal Cord Ser Cases. 2022;8(1):43."},{"issue":"5","key":"bib5","series-title":"Br J Neurosurg","first-page":"691","article-title":"Disseminated spinal myxopapillary ependymoma in an adult at initial presentation: a case report and review of the literature","volume":"28","author":"Straus","year":"2014","unstructured":"Straus DTan LATakagi IO\u2019Toole JE.Disseminated spinal myxopapillary ependymoma in an adult at initial presentation: a case report and review of the literature. 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