{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:34:24Z","timestamp":1770114864548,"version":"3.49.0"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"13","license":[{"start":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:00:00Z","timestamp":1743379200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cosmet Laser Ther"],"published-print":{"date-parts":[[2025,3,31]]},"abstract":"\n BACKGROUND<\/jats:title>\n Trigeminocardiac reflex (TCR) is a vagal reflex produced by trigeminal nerve stimulation that causes bradycardia, hypotension, and, occasionally, cardiac arrest. TCR usually occurs during surgical manipulation of the posterior fossa. In this report, the authors describe an extremely rare case of TCR that developed when a burr hole was drilled on the temporal bone during surgery for an intraventricular meningioma.<\/jats:p>\n <\/jats:sec>\n \n OBSERVATIONS<\/jats:title>\n The patient was referred to the authors\u2019 department after brain imaging revealed a mass lesion in the right trigone of the lateral ventricle. The surgery, which was performed using a transcortical approach via the right temporal lobe, was conducted under general anesthesia with the patient in the supine lateral position. During craniotomy, the patient experienced 17 seconds of cardiac arrest during the drilling of a burr hole in the temporal bone. TCR could not be diagnosed at that time because it occurred during the manipulation of supratentorial craniotomy with a burr hole. The operation was aborted immediately. The second surgery was performed with the patient in the lateral position, and total removal of the tumor was achieved without causing TCR.<\/jats:p>\n <\/jats:sec>\n \n LESSONS<\/jats:title>\n In this report, the authors describe a rare TCR caused by supratentorial manipulation.<\/jats:p>\n \n https:\/\/thejns.org\/doi\/10.3171\/CASE257<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/case257","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T06:31:24Z","timestamp":1743402684000},"source":"Crossref","is-referenced-by-count":1,"title":["Trigeminocardiac reflex during supratentorial craniotomy for intraventricular meningioma: illustrative case"],"prefix":"10.3171","volume":"9","author":[{"given":"Toshiki","family":"Kawano","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0307-3657","authenticated-orcid":true,"given":"Ryosuke","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8615-6308","authenticated-orcid":true,"given":"Sungchul","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudai","family":"Morisaki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichi","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7278-3978","authenticated-orcid":true,"given":"Shuichi","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1340-3293","authenticated-orcid":true,"given":"Ichiro","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Nara Medical University, Kashihara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"bib1","series-title":"Front Surg","first-page":"989644","article-title":"Prognostic factors for trigeminocardiac reflex during cerebrovascular intervention operation","volume":"9","author":"Sun","year":"2022","unstructured":"Sun ZBhuiyan PLu HQian YXiao H.Prognostic factors for trigeminocardiac reflex during cerebrovascular intervention operation. Front Surg. 2022;9:989644."},{"issue":"3","key":"bib2","series-title":"J Neurosurg Anesthesiol","first-page":"187","article-title":"The trigemino-cardiac reflex: an update of the current knowledge","volume":"21","author":"Schaller","year":"2009","unstructured":"Schaller BCornelius JFPrabhakar HThe trigemino-cardiac reflex: an update of the current knowledge. J Neurosurg Anesthesiol. 2009;21(3):187-195."},{"issue":"3","key":"bib3","series-title":"J Neurosurg Anesthesiol","first-page":"282","article-title":"Brain and heart crosstalk during neurointerventional procedures: the role of the trigeminocardiac reflex: an updated systematic review","volume":"34","author":"Chowdhury","year":"2022","unstructured":"Chowdhury TRizk AAAzazi EAVenkatraghavan LShankar JSSchaller B.Brain and heart crosstalk during neurointerventional procedures: the role of the trigeminocardiac reflex: an updated systematic review. J Neurosurg Anesthesiol. 2022;34(3):282-287."},{"issue":"2","key":"bib4","series-title":"J Neurosurg","first-page":"215","article-title":"Trigeminocardiac reflex during surgery in the cerebellopontine angle","volume":"90","author":"Schaller","year":"1999","unstructured":"Schaller BProbst RStrebel SGratzl O.Trigeminocardiac reflex during surgery in the cerebellopontine angle. J Neurosurg. 1999;90(2):215-220."},{"issue":"7","key":"bib5","series-title":"Acta Neurochir (Wien)","first-page":"727","article-title":"Trigeminocardiac reflex during skull base surgery: mechanism and management","volume":"147","author":"Koerbel","year":"2005","unstructured":"Koerbel AGharabaghi ASamii ATrigeminocardiac reflex during skull base surgery: mechanism and management. Acta Neurochir (Wien). 2005;147(7):727-732."},{"issue":"10","key":"bib6","series-title":"No Shinkei Geka","first-page":"903","article-title":"A case of trigeminocardiac reflex in the pterional approach","volume":"40","author":"Kitabayashi","year":"2012","unstructured":"Kitabayashi MNakamura KMurata T.A case of trigeminocardiac reflex in the pterional approach. No Shinkei Geka. 2012;40(10):903-907."},{"issue":"2","key":"bib7","series-title":"Surg Neurol","first-page":"143","article-title":"The falcine trigeminocardiac reflex: case report and review of the literature","volume":"63","author":"Bauer","year":"2005","unstructured":"Bauer DFYoukilis ASchenck CTurner CRThompson BG.The falcine trigeminocardiac reflex: case report and review of the literature. Surg Neurol. 2005;63(2):143-148."},{"key":"bib8","series-title":"World Neurosurg","first-page":"424","article-title":"Trigeminocardiac reflex: case report and literature review of intraoperative asystole in response to manipulation of the temporalis muscle","volume":"122","author":"Shakil","year":"2019","unstructured":"Shakil HWang APHorth DANair SSReddy KKV.Trigeminocardiac reflex: case report and literature review of intraoperative asystole in response to manipulation of the temporalis muscle. World Neurosurg. 2019;122:424-427."},{"key":"bib1","series-title":"Front Surg","first-page":"989644","article-title":"Prognostic factors for trigeminocardiac reflex during cerebrovascular intervention operation","volume":"9","author":"Sun","year":"2022","unstructured":"Sun ZBhuiyan PLu HQian YXiao H.Prognostic factors for trigeminocardiac reflex during cerebrovascular intervention operation. Front Surg. 2022;9:989644."},{"issue":"3","key":"bib2","series-title":"J Neurosurg Anesthesiol","first-page":"187","article-title":"The trigemino-cardiac reflex: an update of the current knowledge","volume":"21","author":"Schaller","year":"2009","unstructured":"Schaller BCornelius JFPrabhakar HThe trigemino-cardiac reflex: an update of the current knowledge. J Neurosurg Anesthesiol. 2009;21(3):187-195."},{"issue":"3","key":"bib3","series-title":"J Neurosurg Anesthesiol","first-page":"282","article-title":"Brain and heart crosstalk during neurointerventional procedures: the role of the trigeminocardiac reflex: an updated systematic review","volume":"34","author":"Chowdhury","year":"2022","unstructured":"Chowdhury TRizk AAAzazi EAVenkatraghavan LShankar JSSchaller B.Brain and heart crosstalk during neurointerventional procedures: the role of the trigeminocardiac reflex: an updated systematic review. J Neurosurg Anesthesiol. 2022;34(3):282-287."},{"issue":"2","key":"bib4","series-title":"J Neurosurg","first-page":"215","article-title":"Trigeminocardiac reflex during surgery in the cerebellopontine angle","volume":"90","author":"Schaller","year":"1999","unstructured":"Schaller BProbst RStrebel SGratzl O.Trigeminocardiac reflex during surgery in the cerebellopontine angle. J Neurosurg. 1999;90(2):215-220."},{"issue":"7","key":"bib5","series-title":"Acta Neurochir (Wien)","first-page":"727","article-title":"Trigeminocardiac reflex during skull base surgery: mechanism and management","volume":"147","author":"Koerbel","year":"2005","unstructured":"Koerbel AGharabaghi ASamii ATrigeminocardiac reflex during skull base surgery: mechanism and management. Acta Neurochir (Wien). 2005;147(7):727-732."},{"issue":"10","key":"bib6","series-title":"No Shinkei Geka","first-page":"903","article-title":"A case of trigeminocardiac reflex in the pterional approach","volume":"40","author":"Kitabayashi","year":"2012","unstructured":"Kitabayashi MNakamura KMurata T.A case of trigeminocardiac reflex in the pterional approach. No Shinkei Geka. 2012;40(10):903-907."},{"issue":"2","key":"bib7","series-title":"Surg Neurol","first-page":"143","article-title":"The falcine trigeminocardiac reflex: case report and review of the literature","volume":"63","author":"Bauer","year":"2005","unstructured":"Bauer DFYoukilis ASchenck CTurner CRThompson BG.The falcine trigeminocardiac reflex: case report and review of the literature. Surg Neurol. 2005;63(2):143-148."},{"key":"bib8","series-title":"World Neurosurg","first-page":"424","article-title":"Trigeminocardiac reflex: case report and literature review of intraoperative asystole in response to manipulation of the temporalis muscle","volume":"122","author":"Shakil","year":"2019","unstructured":"Shakil HWang APHorth DANair SSReddy KKV.Trigeminocardiac reflex: case report and literature review of intraoperative asystole in response to manipulation of the temporalis muscle. World Neurosurg. 2019;122:424-427."}],"container-title":["Journal of Neurosurgery: Case Lessons"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/13\/article-CASE257.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/13\/article-CASE257.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-case-lessons\/9\/13\/article-CASE257.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T23:40:45Z","timestamp":1770075645000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-case-lessons\/9\/13\/article-CASE257.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,31]]},"references-count":16,"journal-issue":{"issue":"13"},"URL":"https:\/\/doi.org\/10.3171\/case257","relation":{},"ISSN":["2694-1902"],"issn-type":[{"value":"2694-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,31]]}}}