{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:07:15Z","timestamp":1779361635505,"version":"3.51.4"},"reference-count":46,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"17","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurosurg Case Lessons"],"published-print":{"date-parts":[[2026,4,27]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Germ cell tumors have a low incidence in the Hispanic population and most frequently present in pineal or suprasellar regions. Only a few cases have been reported with an initial image compatible with a meningioma-like appearance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 24-year-old male with photopsias, headache, and left homonymous hemianopia presented with a right parieto-occipital extra-axial mass. MRI revealed a heterogeneous enhancing mass, with hemorrhagic zones and surrounding vasogenic edema. Surgery with a near-total resection was performed and an extra-axial lesion with infiltration of the deep venous system was found. Histopathological evaluation revealed a mixed germ cell tumor with a yolk sac tumor and immature teratoma. Postoperative investigation revealed elevated serum \u03b1-fetoprotein and pulmonary metastasis. Radiotherapy and chemotherapy followed surgical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>Germ cell tumors can present as extra-axial dura-based lesions and should be suspected in young patients with imaging showing lesions with cystic or hemorrhagic components. Pulmonary metastases are infrequent but may be present. For successful treatment, chemotherapy and radiation therapy should always be considered.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE25855\">https:\/\/thejns.org\/doi\/10.3171\/CASE25855<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case25855","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:39:17Z","timestamp":1779359957000},"source":"Crossref","is-referenced-by-count":0,"title":["Intracranial mixed germ cell tumor mimicking a meningioma: illustrative case"],"prefix":"10.3171","volume":"11","author":[{"given":"Flavio","family":"Hern\u00e1ndez Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Neurosurgery Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Ch\u00e1vez Pe\u00f3n P\u00e9rez","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mart\u00edn R.","family":"De Le\u00f3n Salazar","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blas E.","family":"L\u00f3pez F\u00e9lix","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia","family":"Hop Garc\u00eda","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Arrucha Cozaya","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erick U.","family":"Zepeda Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Hospital de Especialidades, Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"8","key":"bib1","series-title":"Neuro Oncol","first-page":"1231","article-title":"The 2021 WHO Classification of Tumors of the Central Nervous System: a summary","volume":"23","author":"Louis","year":"2021","unstructured":"Louis DNPerry AWesseling PThe 2021 WHO Classification of Tumors of the Central Nervous System: a summary. 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J Neurooncol. 2010;96(2):143-149. doi:10.1007\/s11060-009-9951-z"},{"issue":"3","key":"bib23","series-title":"J Neurosurg","first-page":"446","article-title":"Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases","volume":"86","author":"Matsutani","year":"1997","unstructured":"Matsutani MSano KTakakura KPrimary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases. J Neurosurg. 1997;86(3):446-455. doi:10.3171\/jns.1997.86.3.0446"},{"issue":"8","key":"bib1","series-title":"Neuro Oncol","first-page":"1231","article-title":"The 2021 WHO Classification of Tumors of the Central Nervous System: a summary","volume":"23","author":"Louis","year":"2021","unstructured":"Louis DNPerry AWesseling PThe 2021 WHO Classification of Tumors of the Central Nervous System: a summary. 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