{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T16:07:06Z","timestamp":1776096426499,"version":"3.50.1"},"reference-count":42,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"12","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurosurg Case Lessons"],"published-print":{"date-parts":[[2026,3,23]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Sphenoid sinus mucocele is a rare type of paranasal sinus lesions that can occasionally cause neurological deficits such as optic and oculomotor nerve deficits. However, internal carotid artery (ICA) stenosis associated with sphenoid sinus mucocele is extremely uncommon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBSERVATIONS<\/jats:title>\n                    <jats:p>A 36-year-old man with a history of craniotomy for Rathke\u2019s cleft cyst in childhood presented with rapidly progressive right-sided retro-orbital pain, ptosis, and diplopia. CT and MRI revealed a cystic lesion occupying the sphenoid sinus with adjacent ICA stenosis that markedly worsened within 4 days. Emergency endoscopic transnasal cyst fenestration was performed, and the mucinous contents were evacuated. The cyst wall adhered tightly to the dura of the sella turcica and the wall of the ICA. Postoperatively, the patient\u2019s visual and oculomotor nerve deficits resolved, and follow-up imaging demonstrated rapid improvement of the ICA stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>LESSONS<\/jats:title>\n                    <jats:p>This case illustrates that sphenoid sinus mucocele can lead to rapid progression of neurological deficits and ICA stenosis. Diagnosis based on imaging only may be challenging; however, timely recognition and prompt surgical intervention are crucial, as simple cyst fenestration can achieve complete neurological recovery and prevent severe major artery stenosis.<\/jats:p>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/thejns.org\/doi\/10.3171\/CASE25932\">https:\/\/thejns.org\/doi\/10.3171\/CASE25932<\/jats:ext-link>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/case25932","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:04:23Z","timestamp":1775642663000},"source":"Crossref","is-referenced-by-count":0,"title":["Rapidly progressive visual impairment and internal carotid artery stenosis caused by sphenoid sinus mucocele: illustrative case"],"prefix":"10.3171","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7032-2242","authenticated-orcid":true,"given":"Koki","family":"Nakazato","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi, Gunma"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8669-3113","authenticated-orcid":true,"given":"Rei","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi, Gunma"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8784-601X","authenticated-orcid":true,"given":"Naoto","family":"Mukada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi, Gunma"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4430-751X","authenticated-orcid":true,"given":"Masahiko","family":"Tosaka","sequence":"additional","affiliation":[{"name":"Department of Pituitary and Hypothalamic Surgery, Toranomon Hospital, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0842-5092","authenticated-orcid":true,"given":"Soichi","family":"Oya","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Gunma University Graduate School of Medicine, Maebashi, Gunma"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"3-4","key":"bib1","series-title":"Acta Neurochir (Wien)","first-page":"114","article-title":"Mucocele of neurosurgical interest: clinical considerations on five cases","volume":"102","author":"Pompili","year":"1990","unstructured":"Pompili AMastrostefano RCaroli FMucocele of neurosurgical interest: clinical considerations on five cases. Acta Neurochir (Wien). 1990;102(3-4):114-121. doi:10.1007\/BF01405424"},{"issue":"1","key":"bib2","series-title":"Head Neck Pathol","first-page":"75","article-title":"Ectopic sphenoid sinus pituitary adenoma (ESSPA) with normal anterior pituitary gland: a clinicopathologic and immunophenotypic study of 32 cases with a comprehensive review of the English literature","volume":"6","author":"Thompson","year":"2012","unstructured":"Thompson LDRSeethala RRM\u00fcller S.Ectopic sphenoid sinus pituitary adenoma (ESSPA) with normal anterior pituitary gland: a clinicopathologic and immunophenotypic study of 32 cases with a comprehensive review of the English literature. 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Br J Ophthalmol. 1992;76(8):502-504. doi:10.1136\/bjo.76.8.502"},{"issue":"4","key":"bib17","series-title":"In vivo (Athens, Greece)","first-page":"1947","article-title":"Visual acuity impairment from inflammatory isolated sphenoid sinus disease","volume":"38","author":"Huang","year":"2024","unstructured":"Huang CYHou TYYang YFLin YH.Visual acuity impairment from inflammatory isolated sphenoid sinus disease. In vivo (Athens, Greece). 2024;38(4):1947-1956. doi:10.21873\/invivo.13651"},{"issue":"3","key":"bib18","series-title":"J Neurosurg","first-page":"351","article-title":"Mucocele of the sphenoid sinus with bilateral internal carotid artery occlusion. Case report","volume":"36","author":"Doyle","year":"1972","unstructured":"Doyle CSSimeone FA.Mucocele of the sphenoid sinus with bilateral internal carotid artery occlusion. Case report. 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