{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T09:09:54Z","timestamp":1779527394629,"version":"3.53.1"},"reference-count":60,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:p>The authors describe a technique for minimally invasive anterior vertebroplasty for treating metastatic disease of the C-2 vertebra and discuss its application in 2 cases. After a 2-cm lateral neck incision is made, blunt dissection is performed toward the anterior inferior endplate of the C-2 vertebra. An 11-gauge needle is introduced through a tubular sheath and tapped into the inferior endplate of C-2, with biplanar fluoroscopy being performed to confirm position. The needle is subsequently advanced across the fracture line and into the odontoid process. Under fluoroscopic guidance, 2 ml of methylmethacrylate is injected into the odontoid process and vertebral body. This method is advantageous as 1) hyperextension of the neck is not performed, 2) the chance of inadvertent neurovascular or submandibular gland injury is minimized, 3) the possibility of cement leakage is decreased, and 4) hemostasis is better achieved under direct vision.<\/jats:p>","DOI":"10.3171\/foc\/2008\/25\/8\/e4","type":"journal-article","created":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T13:41:46Z","timestamp":1217598106000},"page":"E4","source":"Crossref","is-referenced-by-count":10,"title":["Minimally invasive anterior vertebroplasty for C-2 metastatic lesions"],"prefix":"10.3171","volume":"25","author":[{"given":"Richard","family":"Rhiew","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Manjila","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"DeZure","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monir","family":"Tabbosha","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murali","family":"Guthikonda","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazem","family":"Eltahawy","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Wayne State University, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0250004","series-title":"Eur Radiol","first-page":"850","article-title":"Minimally invasive treatment of C2 odontoid traumatic fracture with transoral percutaneous vertebroplasty","volume":"17","author":"Anselmetti","year":"2007"},{"key":"b2-0250004","series-title":"Radiology","first-page":"354","article-title":"Percutaneous vertebroplasty for spinal metastases: complications","volume":"238","author":"Barrag\u00e1n-Campos","year":"2006"},{"key":"b3-0250004","series-title":"AJNR Am J Neuroradiol","first-page":"179","article-title":"Major complications of percutaneous embolization of skull-base tumors","volume":"20","author":"Casasco","year":"1999"},{"key":"b4-0250004","series-title":"AJNR Am J Neuroradiol","first-page":"1738","article-title":"Catheter-directed percutaneous transpedicular C2\/C3 vertebroplasty in a patient with fibrous dysplasia using Seldinger technique","volume":"27","author":"Christoforidis","year":"2006"},{"key":"b5-0250004","series-title":"Rev Rhum Engl Ed","first-page":"177","article-title":"Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma","volume":"64","author":"Cortet","year":"1997"},{"key":"b6-0250004","series-title":"Radiology","first-page":"525","article-title":"Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up","volume":"200","author":"Cotten","year":"1996"},{"issue":"16 Suppl","key":"b7-0250004","series-title":"Eur Spine J","first-page":"250","article-title":"C2\/C3 pathologic fractures from polyostotic fibrous dysplasia of the cervical spine treated with percutaneous vertebroplasty","volume":"3","author":"Dang","year":"2007"},{"key":"b8-0250004","series-title":"J Neuroradiol","first-page":"123","article-title":"[Percutaneous vertebroplasty of the cervicothoracic junction using an anterior route. 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Report of nine cases.]","volume":"25","author":"Dufresne","year":"1998"},{"issue":"2 Suppl","key":"b9-0250004","series-title":"J Neurosurg","first-page":"165","article-title":"Management of atlantoaxial metastases with posterior occipitocervical stabilization","volume":"93","author":"Fourney","year":"2003"},{"key":"b10-0250004","series-title":"J Vasc Inter Radiol","first-page":"340","article-title":"Transoral vertebroplasty for a fractured C2 aneurysmal bone cyst","volume":"13","author":"Gailloud","year":"2002"},{"key":"b11-0250004","series-title":"Sem Intervent Radiol","first-page":"137","article-title":"Computed tomography (CT) and fluoroscopy-guided vertebroplasty: results and complications in 187 patients","volume":"16","author":"Gangi","year":"1999"},{"key":"b12-0250004","series-title":"Acta Radiol","first-page":"256","article-title":"Percutaneous vertebroplasty: indications, contraindications, technique and complications","volume":"46","author":"Guglielmi","year":"2005"},{"key":"b13-0250004","series-title":"Clin Radiol","first-page":"461","article-title":"Percutaneous vertebroplasty: history, technique and current perspectives","volume":"59","author":"Hide","year":"2004"},{"key":"b14-0250004","series-title":"Clin Orthop Relat Res","first-page":"89","article-title":"Metastatic disease of the cervical spine. 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vertebroplasty","volume":"17","author":"Anselmetti","year":"2007"},{"key":"b2-0250004","series-title":"Radiology","first-page":"354","article-title":"Percutaneous vertebroplasty for spinal metastases: complications","volume":"238","author":"Barrag\u00e1n-Campos","year":"2006"},{"key":"b3-0250004","series-title":"AJNR Am J Neuroradiol","first-page":"179","article-title":"Major complications of percutaneous embolization of skull-base tumors","volume":"20","author":"Casasco","year":"1999"},{"key":"b4-0250004","series-title":"AJNR Am J Neuroradiol","first-page":"1738","article-title":"Catheter-directed percutaneous transpedicular C2\/C3 vertebroplasty in a patient with fibrous dysplasia using Seldinger technique","volume":"27","author":"Christoforidis","year":"2006"},{"key":"b5-0250004","series-title":"Rev Rhum Engl Ed","first-page":"177","article-title":"Percutaneous vertebroplasty in patients with osteolytic metastases or multiple 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