{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:30:19Z","timestamp":1790368219363,"version":"4.1.0"},"reference-count":49,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>The authors report a series of 22 patients in whom major complications developed after cervical spinal manipulation therapy (CSMT). A second objective was to estimate the regional incidence of these complications and to compare it with the very low incidences reported in the literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>During a 5-year period, practioners at a single group neurosurgical practice in Tulsa, Oklahoma, treated 22 patients, who were markedly worse during, or immediately after, CSMT. The details of these cases are reported. The 1995 US Government National Census was used to define the regional referral population for Tulsa. The published data regarding the incidence of serious CSMT-related complications and the rate of CSMTs undertaken nationally were used to estimate the expected number of CSMT-related complications in the authors' region. The number (22 cases) reported in this series was used to estimate the actual regional incidence.<\/jats:p>\n                    <jats:p>Complications in the series included radiculopathy (21 cases), myelopathy (11 cases), Brown\u2013S\u00e9quard syndrome (two cases), and vertebral artery (VA) occlusion (one case). Twenty-one patients underwent surgery. Poor outcomes were observed in three, outcome was unchanged in one, and 17 improved. The number of patients in this series exceeded the expected number for the region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cervical spinal manipulation therapy may worsen preexisting cervical disc herniation or cause disc herniation resulting in radiculopathy, myelopathy, or VA compression. In cases of cervical spondylosis, CSMT may also worsen preexisting myelopathy or radiculopathy. Manipulation of the cervical spine may also be associated with higher complication rates than previously reported.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/foc.2002.13.6.8","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T06:58:29Z","timestamp":1201157909000},"page":"1-8","source":"Crossref","is-referenced-by-count":29,"title":["Complications of cervical spine manipulation therapy: 5-year retrospective study in a single-group practice"],"prefix":"10.3171","volume":"13","author":[{"given":"David G.","family":"Malone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevan G.","family":"Baldwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.","family":"Tomecek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Boxell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven E.","family":"Gaede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher G.","family":"Covington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenyon K.","family":"Kugler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"p_1","first-page":"181","volume":"15","author":"Anderson R","year":"1992","journal-title":"J Manipulative Physiol Ther"},{"key":"p_2","first-page":"475","volume":"42","author":"Assendelft WJ","year":"1996","journal-title":"J Fam Pract"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-197703000-00014"},{"key":"p_4","first-page":"177","volume":"17","author":"Beneliyahu DJ","year":"1994","journal-title":"J Manipulative Physiol Ther"},{"key":"p_5","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1001\/jama.1925.02670180012003","volume":"85","author":"Blaine ES","year":"1925","journal-title":"JAMA"},{"key":"p_6","first-page":"119","volume":"17","author":"Brouillette DL","year":"1994","journal-title":"J Manipulative Physiol Ther"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198602000-00007"},{"key":"p_8","first-page":"129","volume":"6","author":"Carrick FR","year":"1983","journal-title":"J Manipulative Pysiol Ther"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-6757(98)90236-4"},{"key":"p_10","first-page":"530","volume":"18","author":"Dabbs V","year":"1995","journal-title":"J Manipulative Pysiol Ther"},{"key":"p_11","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1136\/jnnp.52.9.1113","volume":"52","author":"Destee A","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"p_12","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0002-9394(14)71144-4","volume":"123","author":"Donzis PB","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"p_13","first-page":"549","author":"Dvorak J","year":"1992","journal-title":"Principles and Practice of Chiropractic. 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