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The pathophysiological causes of TN remain incompletely understood, but the medical and surgical treatment techniques currently used offer effective ways to relieve this extremely painful condition. In this historical review the authors discuss the initial descriptions of tic douloureux, Fothergill disease, and TN, along with various therapeutic interventions and their refinements.<\/jats:p>","DOI":"10.3171\/foc.2005.18.5.5","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T07:06:10Z","timestamp":1201158370000},"page":"1-10","source":"Crossref","is-referenced-by-count":71,"title":["Historical perspectives on the diagnosis and treatment of trigeminal neuralgia"],"prefix":"10.3171","volume":"18","author":[{"given":"Chad D.","family":"Cole","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald I.","family":"Apfelbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(65)90074-2"},{"key":"p_3","first-page":"407","author":"Apfelbaum R","year":"1999","journal-title":"Lippincott-Raven"},{"key":"p_4","first-page":"898","author":"Apfelbaum R","year":"2002","journal-title":"New York: Thieme"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-197707000-00003"},{"key":"p_6","first-page":"473","volume":"46","author":"Apfelbaum RI","year":"2000","journal-title":"Clin Neurosurg"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1007\/BF01420050"},{"key":"p_8","first-page":"93","volume":"4","author":"Baker KA","year":"1985","journal-title":"Clin Pharm"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604253341701"},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.3.0359"},{"key":"p_11","first-page":"34","volume":"63","author":"Bergouignan M","year":"1942","journal-title":"Rev Laryngol Otol Rhinol"},{"key":"p_12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(62)91847-0"},{"key":"p_13","doi-asserted-by":"publisher","DOI":"10.3171\/foc.1996.1.2.5"},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.90.5.0977"},{"key":"p_15","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.3.297"},{"key":"p_16","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1001\/jama.1900.24610170013001c","volume":"34","author":"Cushing H","year":"1900","journal-title":"JAMA"},{"key":"p_17","first-page":"1","author":"Dandy WE","year":"1963","journal-title":"MD: WF Prior"},{"key":"p_18","first-page":"105","volume":"36","author":"Dandy WE","year":"1925","journal-title":"Bull Johns Hopkins Hosp"},{"key":"p_19","doi-asserted-by":"publisher","DOI":"10.1093\/jhmas\/XII.1.21"},{"key":"p_20","first-page":"129","volume":"1773","author":"Fothergill J","journal-title":"London: T Cadell"},{"key":"p_21","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410150306"},{"key":"p_22","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1962.19.11.0947"},{"key":"p_23","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1001\/jama.1959.03010150017004","volume":"170","author":"Gardner WJ","year":"1959","journal-title":"JAMA"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198112000-00005"},{"key":"p_25","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/63.3.209"},{"key":"p_26","first-page":"582","volume":"10","author":"H\u00e4rtel F","year":"1914","journal-title":"Med Klinik"},{"key":"p_27","first-page":"317","volume":"55","author":"Hartley F","year":"1892","journal-title":"NY Med J"},{"key":"p_28","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1136\/bmj.2.1613.1139","volume":"2","author":"Horsley V","journal-title":"Br Med J"},{"key":"p_31","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1966.25.2.0153"},{"key":"p_32","first-page":"761","volume":"167","author":"Kirschner M","year":"1931","journal-title":"Zur Elektrochirurgie. 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