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The father's sister had been treated at another institution for a posterior fossa ependymoma. The association of ependymomas with molecular genetic alterations in chromosome 22 has been previously described. Further investigation of the genetic influences may lead to better therapeutic approaches for this relatively rare clinicopathological entity.<\/jats:p>","DOI":"10.3171\/foc.2006.20.1.9","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T07:14:03Z","timestamp":1201158843000},"page":"1-5","source":"Crossref","is-referenced-by-count":18,"title":["Familial intracranial ependymomas"],"prefix":"10.3171","volume":"20","author":[{"given":"Vassilios G.","family":"Dimopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostas N.","family":"Fountas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe Sam","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"p_1","first-page":"263","volume":"33","author":"Acqui M","year":"1989","journal-title":"J Neurosurg Sci"},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01669853"},{"key":"p_3","first-page":"136","volume":"47","author":"Bhatt AR","year":"1999","journal-title":"Neurol India"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870130407"},{"key":"p_6","first-page":"317","author":"Burger PC","year":"1994","journal-title":"Atlas of Tumor Pathology. 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