{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:59:25Z","timestamp":1792735165727,"version":"4.5.0"},"reference-count":42,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Conventional imaging demonstrates intertwined fibers of the cerebral white matter as a homogeneous substrate. Recently, diffusion tensor imaging has allowed 3D reconstruction of these fiber bundles. The goal of this study was to analyze the modifications of the association fibers induced by an arteriovenous malformation (AVM) in the parietotemporooccipital (PTO) associative area and their clinical significance.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors analyzed the long association fibers in seven patients harboring an AVM in or near the PTO region in relation with the fibers' clinical manifestation. The fibers include the arcuate fasciculus (AF), the occipitofrontal fasciculus (OFF), and the inferior longitudinal fasciculus (ILF). These structures were compared with the contra-lateral bundles.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The modification of the tracts could establish a pattern signature depending on the specific location of the vascular malformation. There was a positive correlation between the degree of modifications of OFF and ILF fiber tracts and visual deficits. Alteration of the AF correlated with a speech disorder and the risk of postoperative deficits.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Diffusion tensor imaging enables in vivo dissection of fiber tracts coursing through the PTO area. Depending on the location of the AVMs, long association fibers are variously modified. These findings correlate with clinical manifestations and may predict outcome after surgery.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns-07\/09\/0509","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:54:10Z","timestamp":1201179250000},"page":"509-514","source":"Crossref","is-referenced-by-count":16,"title":["Diffusion tensor imaging analysis of long association bundles in the presence of an arteriovenous malformation"],"prefix":"10.3171","volume":"107","author":[{"given":"Jos\u00e9e","family":"B\u00e9rub\u00e9","sequence":"first","affiliation":[{"name":"Department of Physiology, University of Montr\u00e9al; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Mclaughlin","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Bourgouin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al\u2013H\u00f4pital Notre-Dame, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Beaudoin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al\u2013H\u00f4pital Notre-Dame, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel W.","family":"Bojanowski","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1070509","series-title":"J Comput Assist Tomogr","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1097\/01.rct.0000148453.29579.51","article-title":"Diffusion tensor tractography of gliomatosis cerebri: fiber tracking through the tumor","volume":"29","author":"Akai","year":"2005"},{"key":"b2-1070509","series-title":"AJNR Am J Neuroradiol","first-page":"1423","article-title":"Plasticity of the human motor cortex in patients with arteriovenous malformations: a functional MR imaging study","volume":"21","author":"Alkadhi","year":"2000"},{"key":"b3-1070509","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1016\/j.neuroimage.2005.05.014","article-title":"Flow-based fiber tracking with diffusion tensor and q-ball data: validation and comparison to principal diffusion direction techniques","volume":"27","author":"Campbell","year":"2005"},{"key":"b4-1070509","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1006\/nimg.2002.1136","article-title":"Virtual in vivo interactive dissection of white matter fasciculi in the human brain","volume":"17","author":"Catani","year":"2002"},{"key":"b5-1070509","series-title":"Brain","doi-asserted-by":"publisher","first-page":"2093","DOI":"10.1093\/brain\/awg203","article-title":"Occipitotemporal connections in the human brain","volume":"126","author":"Catani","year":"2003"},{"key":"b6-1070509","series-title":"J Neuroradiol","first-page":"25","article-title":"[Diffusion, perfusion and activation functional MRI studies of brain arteriovenous malformations.]","volume":"31","author":"Ducreux","year":"2004"},{"key":"b7-1070509","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1007\/s00234-005-1389-1","article-title":"Brain MR diffusion tensor imaging and fiber tracking to differentiate between two diffuse axonal injuries","volume":"47","author":"Ducreux","year":"2005"},{"key":"b8-1070509","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"764","DOI":"10.3171\/jns.2003.98.4.0764","article-title":"Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients","volume":"98","author":"Duffau","year":"2003"},{"key":"b9-1070509","series-title":"Brain","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1093\/brain\/awf016","article-title":"Intraoperative mapping of the subcortical language pathways using direct stimulations. 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