{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T03:05:28Z","timestamp":1787972728327,"version":"build-2784847793"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1970,10]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 A clinical and pathological survey of 74 histologically verified ependymomas (47 intracranial, 27 spinal) was derived from a total series of 2186 gliomas. Patient ages ranged from 7 months to 64 years. The malignant tumors above the tentorium tended to occur in patients over 22 years. The greatest frequency occurred with 24 tumors in the fourth ventricle and 20 in the region of the cauda equina. The location, symptomatology, objective findings, surgical and x-ray therapy, and vital statistics have been evaluated. There was no correlation between tumor characteristics and preoperative symptomatology. Supplementary x-ray therapy appeared to be beneficial. Seventeen of the 36 patients with benign intracranial tumors and five of the 11 patients with malignant intracranial tumors survive. Fourteen of the 27 patients with spinal ependymomas survive. There was one instance of generalized metastasis in the spinal series and none in the intracranial group.<\/jats:p>","DOI":"10.3171\/jns.1970.33.4.0428","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T14:29:21Z","timestamp":1241706561000},"page":"428-438","source":"Crossref","is-referenced-by-count":163,"title":["Ependymomas"],"prefix":"10.3171","volume":"33","author":[{"given":"Bartolo M.","family":"Barone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur R.","family":"Elvidge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"A classification of the tumors of the glioma group on a histogenic basis with a correlated study of prognosis","author":"Bailey","year":"1926"},{"key":"b2","series-title":"Brain","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/brain\/54.2.117","article-title":"Observations on the treatment of ependymal gliomas of the spinal cord.","volume":"54","author":"Cairns","year":"1931"},{"key":"b3","series-title":"Intracranial tumors: notes upon a series of two thousand verified cases with surgical mortality, percentages pertaining thereto","author":"Cushing","year":"1932"},{"key":"b4","series-title":"Benign tumors in the third ventricle of the brain; diagnosis and treatment","first-page":"171","author":"Dandy","year":"1933"},{"key":"b5","series-title":"Res. Publs. Ass. nerv. ment. Dis.","first-page":"107","article-title":"The gliomas of the central nervous system. A study of 210 verified cases.","volume":"16","author":"Elvidge","year":"1935"},{"key":"b6","series-title":"Archs Neurol. Psychiat.","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1001\/archneurpsyc.1929.02220010022004","article-title":"Ependymomas: a clinical and pathologic study of 8 cases.","volume":"22","author":"Fincher","year":"1929"},{"key":"b7","series-title":"Res. Publs. Ass. nerv. ment. Dis.","first-page":"182","article-title":"Ependymomas, a study of 109 cases.","volume":"16","author":"Kernohan","year":"1937"},{"key":"b8","series-title":"J. Neurosurg.","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3171\/jns.1964.21.1.0007","article-title":"Intracranial ependymomas; factors influencing prognosis.","volume":"21","author":"Kricheff","year":"1964"},{"key":"b9","series-title":"Archs Neurol. Psychiat.","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1001\/archneurpsyc.1931.02230100063006","article-title":"The classification of gliomas and neuroglia cell types.","volume":"26","author":"Penfield","year":"1931"},{"key":"b10","series-title":"J. Neuropath. exp. Neurol.","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/00005072-194910000-00001","article-title":"Ependymomas and choroid plexus papillomas.","volume":"8","author":"Ringertz","year":"1949"},{"key":"b11","series-title":"Pathology of tumours of the nervous system","author":"Russell","year":"1959"},{"key":"b12","series-title":"Post-grad. med. J.","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1136\/pgmj.26.293.109","article-title":"Pathology of intracranial tumours.","volume":"26","author":"Russell","year":"1950"},{"key":"b13","series-title":"Atlas of tumor pathology","article-title":"Tumors of the peripheral nervous system.","author":"Stout","year":"1949"},{"key":"b14","series-title":"J. Path. Bact.","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1002\/path.1700740214","article-title":"A congenital medulloepithelioma of the mid brain.","volume":"74","author":"Treip","year":"1957"},{"key":"b15","series-title":"J. Neurosurg.","doi-asserted-by":"publisher","first-page":"568","DOI":"10.3171\/jns.1967.27.6.0568","article-title":"Cerebral medulloepithelioma; case report.","volume":"27","author":"Van Epps","year":"1967"},{"key":"b16","series-title":"Brain tumors, their biology and pathology","author":"Zulch","year":"1957"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/33\/4\/article-p428.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/33\/4\/article-p428.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/33\/4\/article-p428.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T09:48:33Z","timestamp":1739612913000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/33\/4\/article-p428.xml"}},"subtitle":["A clinical survey"],"short-title":[],"issued":{"date-parts":[[1970,10]]},"references-count":16,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/jns.1970.33.4.0428","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1970,10]]}}}