{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T22:26:05Z","timestamp":1676759165702},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1971,2]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Intracerebral pO<jats:sub>2<\/jats:sub>, as measured in normal dog brains by a modified mass spectrometer, was found to increase following seizure activity and remain elevated at least 2 hours. These results were found with both drug- and electrically-induced seizures. The pO<jats:sub>2<\/jats:sub> increased to a greater degree in brain tissue rendered ischemic by middle cerebral artery occlusion. A transient reflex hypertension was observed with seizure activity, but hypertension alone failed to produce significant pO<jats:sub>2<\/jats:sub> changes. Since oxidative metabolism has been shown by other investigators to proceed at an elevated rate during seizure activity, the increased pO<jats:sub>2<\/jats:sub> must reflect improved collateral circulation following seizure activity.<\/jats:p>","DOI":"10.3171\/jns.1971.34.2part1.0178","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T14:38:28Z","timestamp":1241707108000},"page":"178-184","source":"Crossref","is-referenced-by-count":3,"title":["Induced seizures as therapy of experimental strokes in dogs"],"prefix":"10.3171","volume":"34","author":[{"given":"Ronald R.","family":"Reed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conrad","family":"Ciesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Owens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neurology (Minneap)","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1212\/WNL.12.12.823","article-title":"Anticoagulant therapy in cerebral infarction: report on cooperative study.","volume":"12","author":"Baker","year":"1962"},{"key":"b2","series-title":"JAMA","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1001\/jama.1969.03160030083010","article-title":"Joint study of extracranial arterial occlusion. 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