{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T17:49:08Z","timestamp":1749577748390},"reference-count":8,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1972,6]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Fifteen patients in whom immediate closure of a myelomeningocele sac was not possible were treated by continuous application of dilute solutions of silver nitrate. Local infection of the sac was prevented or irradicated in 14 of the 15 patients within 72 hours. There were no infections in subsequent shunting procedures. No adverse neurological effects were noted, although the method was usually restricted to patients with neurological deficits below the level of the myelomeningocele sac. One patient who developed persistent hyponatremia and hypochloremia after prolonged application responded well to cessation of the therapy.<\/jats:p>","DOI":"10.3171\/jns.1972.36.6.0769","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T14:43:14Z","timestamp":1241707394000},"page":"769-772","source":"Crossref","is-referenced-by-count":1,"title":["Silver nitrate therapy as an adjunct in the treatment of myelomeningocele"],"prefix":"10.3171","volume":"36","author":[{"given":"Don M.","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Minnesota Med","article-title":"Habilitation of child born with a myelomeningocele defect.","author":"Bensman"},{"key":"b2","series-title":"Dev Med Child Neurol","first-page":"18","article-title":"Is antibiotic prophylaxis necessary in spina bifida.","volume":"6","author":"Bruce","year":"1964"},{"key":"b3","series-title":"Dev Med Child Neurol Suppl","first-page":"51","article-title":"Early closure of myelomeningocele with special reference to leg movement.","volume":"13","author":"Brocklehurst","year":"1967"},{"key":"b4","series-title":"Dev Med Child Neurol","first-page":"39","article-title":"Changes in muscle activity following early closure in myelomeningocele.","volume":"22","author":"Duckworth","year":"1970"},{"key":"b5","series-title":"Mod Management Myelomeningocele","article-title":"Surgical management of myelomeningocele.","author":"Long"},{"key":"b6","series-title":"Dev Med Child Neurol","first-page":"281","article-title":"The effect of dilute silver nitrate and silver protein solutions on the spinal cord and nerve roots: an experimental study on rabbits.","volume":"9","author":"Heiskanen","year":"1967"},{"key":"b7","series-title":"Dev Med Child Neurol Suppl","first-page":"35","article-title":"Survival and paralysis in open myelomeningocele with special reference to the time of repair of the spinal lesion.","volume":"11","author":"Sharrard","year":"1966"},{"key":"b8","series-title":"N Y Med J","first-page":"2656","article-title":"Intensive treatment of fifty children born with myelomeningocele.","volume":"68","author":"Shulman","year":"1968"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/36\/6\/article-p769.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/36\/6\/article-p769.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/36\/6\/article-p769.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T04:37:02Z","timestamp":1668314222000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/36\/6\/article-p769.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,6]]},"references-count":8,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1972.36.6.0769","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1972,6]]}}}