{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T06:33:01Z","timestamp":1725517981764},"reference-count":6,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1973,1]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Subarachnoid hemorrhage was produced in monkeys by injecting fresh arterial blood. Serial angiographic studies of the basilar artery then showed vasospasm, occurring as a biphasic response similar to that seen following subarachnoid hemorrhage in man. Papaverine had previously been found to be the most potent vasodilator for topical use to release spasm resulting from experimentally induced subarachnoid hemorrhage. This drug was therefore administered, in various dilutions, as a slow infusion into the subarachnoid space of these monkeys. In a concentration of 0.03%, papaverine proved to be effective in reducing the vasospasm without toxicity.<\/jats:p>","DOI":"10.3171\/jns.1973.38.1.0020","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T14:55:03Z","timestamp":1241708103000},"page":"20-25","source":"Crossref","is-referenced-by-count":34,"title":["Observations on the effects of intrathecal papaverine in experimental vasospasm"],"prefix":"10.3171","volume":"38","author":[{"given":"Masahiro","family":"Ogata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. M.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. M.","family":"Lougheed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1968.28.1.0001","article-title":"The biphasic response of cerebral vasospasm in experimental subarachnoid hemorrhage.","volume":"28","author":"Brawley","year":"1968"},{"key":"b2","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1965.23.1.0001","article-title":"Spasm of basilar and vertebral arteries caused by experimental subarachnoid hemorrhage.","volume":"23","author":"Echlin","year":"1965"},{"key":"b3","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"357","DOI":"10.3171\/jns.1968.29.4.0357","article-title":"Prolonged experimental cerebral vasospasm.","volume":"29","author":"Simeone","year":"1968"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3171\/jns.1970.33.4.0395","article-title":"Vasospasm in response to repeated subarachnoid hemorrhages in the monkey.","volume":"33","author":"Weir","year":"1970"},{"key":"b5","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3171\/jns.1968.29.2.0121","article-title":"Intracranial arterial spasm: a clinical analysis.","volume":"29","author":"Wilkins","year":"1968"},{"key":"b6","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"260","DOI":"10.3171\/jns.1970.33.3.0260","article-title":"Intracranial arterial spasm in the dog: a chronic experimental model.","volume":"33","author":"Wilkins","year":"1970"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/38\/1\/article-p20.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/38\/1\/article-p20.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/38\/1\/article-p20.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T03:39:56Z","timestamp":1668310796000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/38\/1\/article-p20.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,1]]},"references-count":6,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.1973.38.1.0020","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1973,1]]}}}