{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T20:17:56Z","timestamp":1789503476050,"version":"build-2803163510"},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1975,7]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 A retrospective survey of 41 patients with unbiopsied thalamic, pontine, and medullary tumors treated with radiation therapy demonstrated 30% to 40% 3-year survival, with seven long-term survivors. Eleven of the 12 patients surviving over 3 years have essentially normal neurological function. Of seven patients in whom histological diagnoses were eventually obtained, four proved to have glioblastomas and three low-grade astrocytomas. Autopsy revealed that all glioblastomatous tumors extended beyond the treatment field; this suggested that larger volumes, perhaps the whole brain, should be irradiated. High doses (at least 5000 rads) should be used since the 3-year survival among those receiving such doses was 45%.<\/jats:p>","DOI":"10.3171\/jns.1975.43.1.0065","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:05:23Z","timestamp":1241708723000},"page":"65-68","source":"Crossref","is-referenced-by-count":49,"title":["Radiation of infratentorial and supratentorial brain-stem tumors"],"prefix":"10.3171","volume":"43","author":[{"given":"Fransiska","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Textbook of Radiotherapy","first-page":"247","article-title":"Radiation therapy of tumors and diseases of the nervous system","author":"Bouchard","year":"1966"},{"key":"b2","series-title":"Textbook of Radiotherapy","first-page":"366","article-title":"Radiation therapy of tumors and diseases of the nervous system","author":"Bouchard","year":"1973"},{"key":"b3","series-title":"Neurology (Minneap)","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1212\/WNL.8.1.1","article-title":"Brainstem tumors in children.","volume":"8","author":"Bray","year":"1958"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"505","DOI":"10.3171\/jns.1966.24.2.0505","article-title":"Thalamic tumors.","volume":"24","author":"Cheek","year":"1966"},{"key":"b5","series-title":"Atlas of Tumor Pathology.","author":"Kernohan","year":"1952"},{"key":"b6","series-title":"Acta Radiol (Ther) (Stockh)","first-page":"111","article-title":"Tumor extent as a determining factor in radiotherapy of glioblastomas.","volume":"8","author":"Kramer","year":"1969"},{"key":"b7","series-title":"Lancet","first-page":"913","article-title":"Pontine gliomas of childhood.","volume":"1","author":"Lassman","year":"1967"},{"key":"b8","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1148\/82.2.193","article-title":"Tumors of the posterior fossa in childhood and adolescence. 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