{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T07:44:16Z","timestamp":1698911056538},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1976,1]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The author measured the level of creatine phosphokinase (CPK) in 35 cerebrospinal fluid (CSF) specimens from 30 patients with acute subarachnoid hemorrhage, and correlations were sought with 17 other clinical and laboratory parameters. Elevations of CSF CPK have no diagnostic specificity. However, they do show a statistically significant correlation with the existence of any destructive process in cerebral tissue (hydrocephalus, infarction, intraparenchymal hemorrhage, or intraventricular clot). Yet arterial spasm without infarction does not raise the CSF CPK level. During the preoperative management of ruptured aneurysms and vascular malformations, a significant elevation of the CSF CPK level can thus provide a clue to the presence or significance of one or more of these destructive processes.<\/jats:p>","DOI":"10.3171\/jns.1976.44.1.0050","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:14:00Z","timestamp":1241709240000},"page":"50-54","source":"Crossref","is-referenced-by-count":7,"title":["Cerebrospinal fluid creatine phosphokinase in acute subarachnoid hemorrhage"],"prefix":"10.3171","volume":"44","author":[{"given":"Samuel H.","family":"Greenblatt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Pathol Biol (Paris)","first-page":"847","article-title":"\u00c9tude \u00e9lectrophor\u00e9tique des isozymes de la creatine phosphokinase dans les tissus de l'homme et du lapin.","volume":"18","author":"Allard","year":"1970"},{"key":"b2","series-title":"Acta Radiol (Diag) (Stockh)","first-page":"229","article-title":"Time relationship between subarachnoid hemorrhage, arterial spasm, changes in cerebral circulation and posthaemorrhagic hydrocephalus.","volume":"9","author":"Bergvall","year":"1969"},{"key":"b3","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1956.13.1.0001","article-title":"Hypothermia, and interruption of carotid, or carotid and vertebral circulation, in the surgical management of intracranial aneurysms.","volume":"13","author":"Botterell","year":"1956"},{"key":"b4","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1056\/NEJM197208102870619","article-title":"Elevated serum CPK after drug injections.","volume":"287","author":"Cacace","year":"1972"},{"key":"b5","series-title":"Rev Clin Esp","first-page":"12","article-title":"La creatinfosfoquinasa en el liquido cefalorraquideo de las enfermedades neurologicas no tumorales.","volume":"106","author":"Castello","year":"1967"},{"key":"b6","series-title":"J Biol Chem","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/S0021-9258(19)81450-3","article-title":"The comparative enzymology of creatine kinases. 2. 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