{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:15:49Z","timestamp":1787166949492,"version":"build-2736575974"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1978,7]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The clinical features of 18 cases of suprasellar germinoma were reviewed, and the following points stressed: 1) The incidence of intracranial germinoma and teratoma seems to be much higher in Japan than elsewhere. 2) Germinomas in the pineal region, the third ventricle, and the lateral ventricle were observed to be predominant in males. In suprasellar germinoma, however, males were not affected predominantly and the male:female ratio was 1:1. 3) Suprasellar germinomas caused three symptoms: diabetes insipidus, visual disturbances, and pituitary dysfunctions. 4) Pituitary functions were disturbed to various degrees. Some cases showed hypopituitarism but some showed an elevation of plasma concentrations of cortisol or luteinizing hormone and follicle stimulating hormone. 5) Some abnormalities showing a suprasellar mass were usually found on neuroradiological examination. 6) Suprasellar germinomas were very sensitive to radiotherapy and some of them rapidly disappeared on follow-up computerized tomography scanning after irradiation with as little as 1200 rads.<\/jats:p>","DOI":"10.3171\/jns.1978.49.1.0041","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T11:26:55Z","timestamp":1241695615000},"page":"41-48","source":"Crossref","is-referenced-by-count":87,"title":["Suprasellar germinoma"],"prefix":"10.3171","volume":"49","author":[{"given":"Juji","family":"Takeuchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Handa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izumi","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3171\/jns.1969.30.2.0146","article-title":"Statistical reevaluation of pinealoma and related tumors in Japan.","volume":"30","author":"Araki","year":"1969"},{"key":"b2","series-title":"J Pediatr","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/S0022-3476(61)80009-7","article-title":"Precocious puberty due to secreting chorioepithelioma (teratoma) of the brain.","volume":"59","author":"Bruton","year":"1961"},{"key":"b3","series-title":"Brain","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1093\/brain\/97.1.447","article-title":"Primary suprasellar atypical teratoma.","volume":"97","author":"Camins","year":"1974"},{"key":"b4","series-title":"Endocrinol Jpn (Tokyo)","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1507\/endocrj1954.23.215","article-title":"A female case of the HCG-producing ectopic pinealoma associated with precocious puberty.","volume":"23","author":"Demura","year":"1976"},{"key":"b5","series-title":"J Clin Endocrinol Metab","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1210\/jcem-20-11-1484","article-title":"Significance of the concentration of nonprotein-bound plasma cortisol in normal subjects, Cushing's syndrome, pregnancy, and during estrogen therapy.","volume":"20","author":"Doe","year":"1960"},{"key":"b6","series-title":"Arch Jpn Chir (Kyoto)","first-page":"553","article-title":"Tumors of the diencephalon and precocious puberty.","volume":"27","author":"Fukushima","year":"1958"},{"key":"b7","series-title":"Computed Brain and Orbital Tomography. Technique and Interpretation.","first-page":"86","author":"Gonzalez","year":"1976"},{"key":"b8","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"755","DOI":"10.3171\/jns.1971.35.6.0755","article-title":"Ectopic pinealoma in the region of the optic chiasm. Report of five cases.","volume":"35","author":"Kageyama","year":"1971"},{"key":"b9","series-title":"Neurology","first-page":"318","article-title":"Ectopic pinealoma in the chiasma region.","volume":"11","author":"Kageyama","year":"1961"},{"key":"b10","series-title":"J Clin Invest","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1172\/JCI105358","article-title":"The plasma sugar, free fatty acid, cortisol, and growth hormone response to insulin, and the comparison of this procedure with other tests of pituitary and adrenal function. II. In patients with hypothalamic or pituitary dysfunction or anorexia nervosa.","volume":"45","author":"Landon","year":"1966"},{"key":"b11","series-title":"J Clin Endocrinol Metab","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1210\/jcem-23-3-242","article-title":"Effect of altered thyroid function upon steroid circadian rhythms in man.","volume":"23","author":"Martin","year":"1963"},{"key":"b12","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1148\/120.1.91","article-title":"Evaluation of sellar and parasellar masses by computed tomography.","volume":"120","author":"Naidich","year":"1976"},{"key":"b13","series-title":"Computed Tomography of the Brain and Orbit (EMI Scanner).","first-page":"206","author":"New","year":"1975"},{"key":"b14","series-title":"J Pediatr","first-page":"250","article-title":"Intracranial human chorionic gonadotropin-secreting tumor with precocious puberty.","volume":"86","author":"Romshe","year":"1965"},{"key":"b15","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1148\/85.3.512","article-title":"Ectopic pinealoma: radiocurable neuroendocrinologic entity.","volume":"85","author":"Rubin","year":"1965"},{"key":"b16","series-title":"Am J Pathol","first-page":"787","article-title":"Primary intracranial chorionepithelioma with metastases to the lungs.","volume":"21","author":"Stowell","year":"1945"},{"key":"b17","series-title":"Surg Neurol","first-page":"247","article-title":"Teratomas in the suprasellar region; report of five cases.","volume":"3","author":"Takeuchi","year":"1975"},{"key":"b18","series-title":"Adv Neurol Sci (Tokyo)","first-page":"5","article-title":"[Brain tumor registry in Japan].","volume":"22","year":"1978"},{"key":"b19","series-title":"Proceedings of the 16th General Assembly of the Japan Medical Congress","first-page":"183","article-title":"[Diagnosis and treatment of brain tumors]","volume":"3","author":"Ueki","year":"1963"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/49\/1\/article-p41.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/49\/1\/article-p41.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/49\/1\/article-p41.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T14:23:30Z","timestamp":1660487010000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/49\/1\/article-p41.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,7]]},"references-count":19,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.1978.49.1.0041","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1978,7]]}}}