{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:42:25Z","timestamp":1759542145438},"reference-count":27,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1979,4]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 In rare cases, acromegalic patients have normal basal concentrations of growth hormone, and their acromegaly results from abnormal growth-hormone secretory patterns. A patient is reported with the clinical features of acromegaly, who had elevated somatomedin levels and an enlarged sella turcica, but whose serum growth-hormone levels on continuous monitoring were in the normal range, with levels of 2.8 to 8.9 ng\/ml. Dynamic studies of growth hormone revealed normal responses to hypo- and hyperglycemia, but abnormal responses to L-dopa and thyroid-releasing hormone. At surgery, neither a pituitary adenoma nor eosinophilic hyperplasia was present. It is likely that this patient's acromegaly resulted from the presence of chronically high normal levels of growth hormone.<\/jats:p>","DOI":"10.3171\/jns.1979.50.4.0503","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:36:32Z","timestamp":1241710592000},"page":"503-507","source":"Crossref","is-referenced-by-count":7,"title":["Acromegaly with normal growth-hormone levels and pituitary histology"],"prefix":"10.3171","volume":"50","author":[{"given":"Kenneth R.","family":"Feingold","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira D.","family":"Goldfine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip R.","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Nucl Med","first-page":"740","article-title":"A single method for measuring total thyroxine and free thyroxine index in serum.","volume":"14","author":"Abreau","year":"1973"},{"key":"b2","series-title":"Am J Pathol","first-page":"185","article-title":"Concerning the microscopic structure of the hypophysis cerebri in acromegaly. 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