{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T16:59:19Z","timestamp":1791133159395,"version":"4.1.0"},"reference-count":14,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1980,4]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Eighteen patients with neuropathic pain underwent thalamic electrode implantation. Satisfactory initial pain relief ensued in 14, and their electrode systems were internalized for long-term use. Twelve of the 14 continue to obtain either complete or partial pain relief by regular stimulation. One of the other two patients has had a complete remission of pain, apparently spontaneously, and the other had to have the electrode removed after it retracted from his thalamus on two occasions. The electrodes have been placed in the sensory nucleus of the thalamus where stimulation evokes paresthesias in the painful part of the body. Technical problems consisting of our inability to locate the target in two patients and our failure to fix the electrode adequately in one prevented us from employing the treatment in three patients. The fourth patient had temperature dysesthesia which was not altered during 2 weeks of stimulation.<\/jats:p>","DOI":"10.3171\/jns.1980.52.4.0486","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:44:40Z","timestamp":1241711080000},"page":"486-493","source":"Crossref","is-referenced-by-count":102,"title":["Thalamic stimulation for neuropathic pain"],"prefix":"10.3171","volume":"52","author":[{"given":"Ian M.","family":"Turnbull","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Shulman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Barrie","family":"Woodhurst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Pain","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0304-3959(76)90111-1","article-title":"Naloxone reversal of analgesia produced by brain stimulation in the human.","volume":"2","author":"Adams","year":"1976"},{"key":"b2","series-title":"Appl Neurophysiol","first-page":"111","article-title":"Technique and technical problems associated with implantation of neuroaugmentive devices.","volume":"40","author":"Adams"},{"key":"b3","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"740","DOI":"10.3171\/jns.1974.41.6.0740","article-title":"Stimulation of internal capsule for relief of chronic pain.","volume":"41","author":"Adams","year":"1974"},{"key":"b4","series-title":"Sensory Functions of the Skin.","first-page":"531","article-title":"Effects of multifocal brain stimulation on pain and somatosensory functions","author":"Boethius","year":"1976"},{"key":"b5","series-title":"The Human Somesthetic Thalamus, With Maps for Physiological Target Localization During Stereotactic Neurosurgery.","author":"Emmers","year":"1975"},{"key":"b6","series-title":"Science","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1126\/science.301658","article-title":"Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone.","volume":"197","author":"Hosobuchi","year":"1977"},{"key":"b7","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1001\/archneur.1973.00490270040005","article-title":"Chronic thalamic stimulation for the control of facial anesthesia dolorosa.","volume":"29","author":"Hosobuchi","year":"1973"},{"key":"b8","series-title":"Science","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1126\/science.83674","article-title":"Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid.","volume":"203","author":"Hosobuchi","year":"1979"},{"key":"b9","series-title":"Neurochirurgie","first-page":"117","article-title":"Traitement de certains types de douleurs par des stimulateurs thalamiques implantables.","volume":"20","author":"Mazars","year":"1974"},{"key":"b10","series-title":"Anesthesiology","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1097\/00000542-197110000-00018","article-title":"Phantom limb pain: implications for treatment of pathologic pain.","volume":"35","author":"Melzack","year":"1971"},{"key":"b11","series-title":"Pain","first-page":"195","article-title":"Phantom body pain in paraplegics: evidence for a central \u201cpattern generating mechanism\u201d for pain.","volume":"4","author":"Melzack","year":"1978"},{"key":"b12","series-title":"Appl Neurophysiol","first-page":"57","article-title":"Percutaneous central gray stimulation for cancer pain.","volume":"41","author":"Meyerson","year":"1978"},{"key":"b13","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3171\/jns.1977.47.2.0184","article-title":"Pain reduction by electrical brain stimulation in man. Part 2: Chronic self-administration in the periventricular gray matter.","volume":"47","author":"Richardson","year":"1977"},{"key":"b14","series-title":"Variations and Connections of the Human Thalamus. Vol 2: Variations of the Human Diencephalon.","first-page":"116","author":"Van Buren","year":"1972"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/52\/4\/article-p486.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/52\/4\/article-p486.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/52\/4\/article-p486.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:52:15Z","timestamp":1679273535000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/52\/4\/article-p486.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,4]]},"references-count":14,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/jns.1980.52.4.0486","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1980,4]]}}}