{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T20:42:04Z","timestamp":1772311324955,"version":"3.50.1"},"reference-count":6,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,5]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Most large cerebral arteriovenous malformations (AVM's) in the territories of the penetrating arteries arising from the circle of Willis, including the proximal anterior, middle, and posterior cerebral arteries, have been considered untreatable. However, the pattern of collateral circulation which accompanies these lesions presents the possibility of completely occluding certain segments of the circle of Willis and adjacent major branches without producing infarction distally in the cerebral hemisphere or in the critical areas occupied by the AVM itself. The ensuing reduction of arterial pressure within the AVM may reduce the likelihood of hemorrhage or progressive enlargement. Four patients in whom this was accomplished in whole or in part by embolization are described. In one patient, infarction did ensue but the potential for collateral circulation had been restricted by the passage of emboli into the pericallosal artery. In the others, angiographic filling of the lesion was considerably reduced without worsening of their neurological deficits. One patient had recovery of neurological loss following the procedure, and another was slightly improved. Over follow-up periods of up to 28 months there have been no recurrent hemorrhages or further progression of neurological deficits. However, final assessment of the efficacy of this procedure will require longer follow-up intervals and additional patients.<\/jats:p>","DOI":"10.3171\/jns.1981.54.5.0573","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T13:55:24Z","timestamp":1241790924000},"page":"573-582","source":"Crossref","is-referenced-by-count":33,"title":["Embolization of segments of the circle of Willis and adjacent branches for management of certain inoperable cerebral arteriovenous malformations"],"prefix":"10.3171","volume":"54","author":[{"given":"Alfred J.","family":"Luessenhop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricio H.","family":"Mujica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neurological Surgery","first-page":"181","article-title":"Bragg peak proton treatment of arteriovenous malformations of the brain","author":"Kjellberg","year":"1978"},{"key":"b2","series-title":"Prog Neurol Surg","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1159\/000386096","article-title":"Artificial embolization for cerebral arteriovenous malformations.","volume":"3","author":"Luessenhop","year":"1969"},{"key":"b3","series-title":"Current Controversies in Neurosurgery","first-page":"203","article-title":"Operative treatment of arteriovenous malformations of the brain","author":"Luessenhop","year":"1976"},{"key":"b4","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1227\/00006123-197707000-00007","article-title":"Anatomical grading of supratentorial arteriovenous malformations for determining operability.","volume":"1","author":"Luessenhop","year":"1977"},{"key":"b5","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"443","DOI":"10.3171\/jns.1975.42.4.0443","article-title":"Surgical embolization of cerebral arteriovenous malformations through the internal carotid and vertebral arteries. Long-term results.","volume":"42","author":"Luessenhop","year":"1975"},{"key":"b6","series-title":"Neurological Surgery","first-page":"168","article-title":"Radiosurgery in intracranial arteriovenous malformations. II. A follow-up study","author":"Steiner","year":"1978"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/54\/5\/article-p573.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/54\/5\/article-p573.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/54\/5\/article-p573.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T20:28:33Z","timestamp":1679257713000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/54\/5\/article-p573.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,5]]},"references-count":6,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.1981.54.5.0573","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1981,5]]}}}