{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:43:09Z","timestamp":1791909789225,"version":"4.3.4"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,8]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Reports differ on which nerve fibers are affected by radiofrequency lesions made in peripheral nerves, some stating that primarily the myelinated delta and unmyelinated C fibers are destroyed, others stating that the destruction affects all sizes of nerve fibers and both myelinated and unmyelinated fibers. This study was designed to confirm one of those two findings, and to study the role that different temperatures might play in determining which fibers are affected.<\/jats:p>\n<jats:p content-type=\"fine-print\">Radiofrequency lesions (85\u00b0C for 2 minutes) were made in dogs by placing a temperature-monitored electrode into the lumbar intervertebral foramina. The dogs were killed at intervals up to 6 weeks after rhizotomy, and the lesions were studied by light and electron microscopy. In all lesions, there was a total loss of unmyelinated fibers and a nearly total loss of myelinated fibers. In other dogs, 2-minute lesions were made at 45\u00b0, 55\u00b0, 65\u00b0, and 75\u00b0C, and the lesions examined 1 week later. Again, all sizes and all types of fibers were destroyed.<\/jats:p>","DOI":"10.3171\/jns.1981.55.2.0246","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T13:46:47Z","timestamp":1241790407000},"page":"246-253","source":"Crossref","is-referenced-by-count":159,"title":["Radiofrequency neurolysis in a clinical model"],"prefix":"10.3171","volume":"55","author":[{"given":"Harold P.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe M.","family":"McWhorter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata R.","family":"Challa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Arch Anat Physiol","first-page":"691","author":"Afanassiew","year":"1865"},{"key":"b2","series-title":"Am J Physiol","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1152\/ajplegacy.1908.22.4.456","article-title":"Some observations on the nature of heat paralysis in nervous tissue.","volume":"22","author":"Becht","year":"1908"},{"key":"b3","series-title":"Arch Ges Physiol","first-page":"310","volume":"15","author":"Bernstein","year":"1887"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3171\/jns.1964.21.1.0049","article-title":"Reversible heat lesions with radiofrequency current. A method of stereotactic localization.","volume":"21","author":"Brodkey","year":"1964"},{"key":"b5","series-title":"Johns Hopkins Univ","first-page":"18","article-title":"Studies from the biological laboratory.","volume":"4","author":"Edwards","year":"1887"},{"key":"b6","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1113\/jphysiol.1894.sp000502","article-title":"The effect of stimulation and of changes in temperature upon the irritability and conductivity of nerve-fibres.","volume":"16","author":"Howell","year":"1894"},{"key":"b7","article-title":"Management of spasms and spasticity in spinal cord and brain injured patients by percutaneous radiofrequency rhizotomy.","author":"Kennemore"},{"key":"b8","series-title":"Percutaneous electrocoagulation of spinal nerves for the relief of pain and spasticity","author":"Kennemore","year":"1978"},{"key":"b9","article-title":"Percutaneous radiofrequency spinal rhizotomy for the treatment of pain.","author":"Kennemore"},{"key":"b10","series-title":"Munch Med Wochenschr","first-page":"235","article-title":"Die Behandlung der Trigeminusneuralgie (nach Erfahrungen an 1113 Kranken).","volume":"89","author":"Kirschner","year":"1942"},{"key":"b11","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1113\/jphysiol.1980.sp013095","article-title":"Irreversible differential block of A- and C- fibres following local nerve heating in the cat.","volume":"298","author":"Klumpp","year":"1980"},{"key":"b12","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3171\/jns.1968.29.1.0042","article-title":"The effect of radiofrequency current and heat on peripheral nerve action potential in the cat.","volume":"29","author":"Letcher","year":"1968"},{"key":"b13","series-title":"Rev Neurol","first-page":"201","article-title":"La radicellotomie post\u00e9rieure s\u00e9lective dans le traitement des spasticit\u00e9s.","volume":"130","author":"Sindou","year":"1974"},{"key":"b14","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3171\/jns.1974.40.2.0143","article-title":"Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. Part 1: Trigeminal neuralgia.","volume":"40","author":"Sweet","year":"1974"},{"key":"b15","series-title":"Laryngoscope","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1288\/00005537-197307000-00012","article-title":"Trigeminal neuralgia: new surgical approach. (Percutaneous electrocoagulation of the trigeminal nerve.)","volume":"83","author":"Tew","year":"1973"},{"key":"b16","series-title":"Current Techniques in Operative Neurosurgery.","first-page":"469","article-title":"Percutaneous electrothermocoagulation of spinal nerve trunk, ganglion, and rootlets","author":"Uematsu","year":"1977"},{"key":"b17","series-title":"Surg Neurol","first-page":"319","article-title":"Percutaneous radiofrequency rhizotomy.","volume":"2","author":"Uematsu","year":"1974"},{"key":"b18","series-title":"Pain and the Neurosurgeon: A 40-Year Experience.","first-page":"662","author":"White","year":"1969"},{"key":"b19","series-title":"The Somatosensory System.","first-page":"45","article-title":"Cutaneous C fibers: peripheral properties and central connections","author":"Zimmermann","year":"1975"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/2\/article-p246.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/2\/article-p246.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/2\/article-p246.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T12:18:51Z","timestamp":1658665131000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/2\/article-p246.xml"}},"subtitle":["Neuropathological correlation"],"short-title":[],"issued":{"date-parts":[[1981,8]]},"references-count":19,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/jns.1981.55.2.0246","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1981,8]]}}}