{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:48:46Z","timestamp":1788310126139,"version":"build-2803163510"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,12]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors report the results of internal irradiation with labeled chromic phosphate (<jats:sup>32<\/jats:sup>P) and gold-198 (<jats:sup>198<\/jats:sup>Au) colloid in eight cases of cystic craniopharyngiomas. They used a newly developed dosimetric formula, by which the radiation dose at the cyst wall and at any point far from the radioactive source can be calculated. Ten courses of irradiation in eight patients were carried out by injection of either <jats:sup>32<\/jats:sup>P or <jats:sup>198<\/jats:sup>Au colloid into the cyst through an Ommaya drainage system that had been placed at craniotomy. Follow-up studies ranging from 13 to 156 months revealed that all cysts were effectively treated, with elimination of fluid or collapse of the cyst. This was confirmed by Conray cystography and\/or computerized tomography.<\/jats:p>\n<jats:p content-type=\"fine-print\">Not only the dose delivered to the wall but also the thickness of the cyst wall and the location of the cyst are important factors in planning internal irradiation. A safe and adequate dose to the cyst wall could range between 9000 to 30,000 rads for craniopharyngioma. This treatment is suitable for large cysts that are thought to be difficult to remove radically, recurrent cysts resistant to previous treatment, or multiple cysts. Internal irradiation may also be applicable in other cystic intracranial tumors if dosimetry is calculated accurately.<\/jats:p>","DOI":"10.3171\/jns.1981.55.6.0896","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T13:46:11Z","timestamp":1241790371000},"page":"896-903","source":"Crossref","is-referenced-by-count":63,"title":["Internal irradiation for cystic craniopharyngioma"],"prefix":"10.3171","volume":"55","author":[{"given":"Tatsuya","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kageyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Acta Chir Scand","first-page":"749","article-title":"Studies on craniopharyngiomas. II. 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Technical note.","volume":"27","author":"Fox","year":"1967"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"36","DOI":"10.3171\/jns.1980.52.1.0036","article-title":"Management of the unresectable cystic craniopharyngioma by aspiration through an Ommaya reservoir drainage system.","volume":"52","author":"Gutin","year":"1980"},{"key":"b5","series-title":"Surg Neurol","first-page":"5","article-title":"Forty-five years experience with craniopharyngiomas.","volume":"1","author":"Kahn","year":"1973"},{"key":"b6","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"86","DOI":"10.3171\/jns.1975.42.1.0086","article-title":"Late results of radical excision of craniopharyngiomas in children.","volume":"42","author":"Katz","year":"1975"},{"key":"b7","series-title":"Neurol Med Chir","first-page":"63","article-title":"Pathological and clinical basis of the indications for treatment of craniopharyngioma.","volume":"21","author":"Kobayashi","year":"1981"},{"key":"b8","series-title":"Prog Comput Tomogr","first-page":"101","article-title":"[Conray cystography and volumetry of the cyst using computed tomography.]","volume":"2","author":"Kobayashi","year":"1980"},{"key":"b9","series-title":"Sixth International Congress of Neurological Surgery, S\u00e3o Paulo, Brazil","first-page":"92","article-title":"Treatment of cystic craniopharyngiomas","author":"Kobayashi","year":"1977"},{"key":"b10","series-title":"AJR","doi-asserted-by":"publisher","first-page":"44","DOI":"10.2214\/ajr.103.1.44","article-title":"Radiotherapy in the management of craniopharyngiomas. Further experiences and late results.","volume":"103","author":"Kramer","year":"1968"},{"key":"b11","series-title":"Acta Chir Scand","first-page":"345","article-title":"Treatment of craniopharyngiomas.","volume":"133","author":"Leksell","year":"1967"},{"key":"b12","series-title":"Radioisotope Techniques","first-page":"76","article-title":"A therapeutic trial with radioactive isotopes in cystic brain tumor","volume":"1","author":"Leksell","year":"1953"},{"key":"b13","series-title":"Acta Radiol (Ther)","first-page":"113","article-title":"Radioactive bismuth phosphate for the treatment of craniopharyngioma.","volume":"2","author":"Lindgren","year":"1964"},{"key":"b14","series-title":"Radiation Dosimetry","author":"Loevinger","year":"1956"},{"key":"b15","series-title":"Prog Neurol Surg","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1159\/000386047","article-title":"The treatment of brain tumors with radioisotopes.","volume":"1","author":"Mundinger","year":"1966"},{"key":"b16","series-title":"Nippon Igaku Hoshasen Gakkai Zasshi","first-page":"871","article-title":"[A calculation of dose distribution around 32P spherical sources and its clinical application.]","volume":"37","author":"Ohara","year":"1977"},{"key":"b17","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"707","DOI":"10.3171\/jns.1963.20.8.0707","article-title":"Recurrent cystic formation in craniopharyngioma treated with radioactive chromic phosphate. 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Treatment of a cystic craniopharyngioma by injection of radioactive P32.","volume":"14","author":"Wycis","year":"1954"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/6\/article-p896.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/6\/article-p896.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/6\/article-p896.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T12:27:54Z","timestamp":1658665674000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/6\/article-p896.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,12]]},"references-count":19,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1981.55.6.0896","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1981,12]]}}}