{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:11:51Z","timestamp":1791893511057,"version":"4.3.4"},"reference-count":22,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,12]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Patients with intracranial disorders are prone to develop hyponatremia with inability to prevent the loss of sodium in their urine. This was originally referred to as \u201ccerebral salt wasting,\u201d but more recently is thought to be secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Blood volume determinations were made in 12 unselected neurosurgical patients with intracranial disease who fulfilled the laboratory criteria for SIADH. Ten of the 12 patients had significant decreases in their red blood cell mass, plasma volume, and total blood volume. The finding of a decreased blood volume in patients who fulfill the laboratory criteria for SIADH is better explained by the original concepts of cerebral salt wasting than by SIADH. The primary defect may be the inability of the kidney to conserve sodium.<\/jats:p>","DOI":"10.3171\/jns.1981.55.6.0938","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T13:46:11Z","timestamp":1241790371000},"page":"938-941","source":"Crossref","is-referenced-by-count":214,"title":["Hyponatremia in intracranial disease: perhaps not the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)"],"prefix":"10.3171","volume":"55","author":[{"given":"Paul B.","family":"Nelson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said M.","family":"Seif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph C.","family":"Maroon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan G.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"DM","first-page":"1","article-title":"The syndrome of inappropriate secretion of antidiuretic hormone (SIADH).","author":"Bartter","year":"1973"},{"key":"b2","series-title":"Arch Intern Med","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1001\/archinte.1965.03870010115014","article-title":"Cerebral salt-wasting associated with the Guillain-Barr\u00e9 syndrome.","volume":"116","author":"Cooper","year":"1965"},{"key":"b3","series-title":"Lancet","first-page":"752","article-title":"Cerebral salt wasting.","volume":"1","author":"Cort","year":"1954"},{"key":"b4","series-title":"Brain","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1093\/brain\/86.2.301","article-title":"Hypothalamic lesions following the rupture of cerebral berry aneurysms.","volume":"86","author":"Crompton","year":"1963"},{"key":"b5","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"506","DOI":"10.3171\/jns.1971.34.4.0506","article-title":"Neurosurgical hyponatremia: the role of inappropriate antidiuresis.","volume":"34","author":"Fox","year":"1971"},{"key":"b6","series-title":"J Pediatr","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/S0022-3476(79)80003-7","article-title":"Antidiuretic hormone excess.","volume":"94","author":"Friedman","year":"1979"},{"key":"b7","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"627","DOI":"10.3171\/jns.1977.46.5.0627","article-title":"Release of antidiuretic hormone during mass-induced elevation of intracranial pressure.","volume":"46","author":"Gaufin","year":"1977"},{"key":"b8","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1056\/NEJM196011242632101","article-title":"Hyponatremia and renal wasting of sodium in patients with malfunction of the central nervous system.","volume":"263","author":"Goldberg","year":"1960"},{"key":"b9","series-title":"Am J Med Sci","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1097\/00000441-196504000-00003","article-title":"Cerebral hyponatremia with inappropriate antidiuretic hormone syndrome.","volume":"249","author":"Haden","year":"1965"},{"key":"b10","series-title":"Acta Neurol Scand","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1111\/j.1600-0404.1967.tb05759.x","article-title":"Head injury followed by transient hyponatremia probably caused by inappropriate antidiuresis.","volume":"43","author":"Hald","year":"1967"},{"key":"b11","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1001\/archneur.1965.00470060069007","article-title":"Hyponatremia in subarachnoid hemorrhage.","volume":"13","author":"Joynt","year":"1965"},{"key":"b12","series-title":"Nephron","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1159\/000180522","article-title":"Natriuretic hormone.","volume":"15","author":"Klahr","year":"1975"},{"key":"b13","series-title":"J Clin Invest","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1172\/JCI102805","article-title":"Evidence in man that urinary electrolyte loss induced by pitressin is a function of water retention.","volume":"32","author":"Leaf","year":"1953"},{"key":"b14","series-title":"Pediatr","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1542\/peds.34.4.503","article-title":"Studies of sustained hyponatremia due to central nervous system infection.","volume":"34","author":"Mangos","year":"1964"},{"key":"b15","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1001\/archneur.1970.00480210044005","article-title":"Subdural hematoma with inappropriate antidiuretic hormone secretion.","volume":"22","author":"Maroon","year":"1970"},{"key":"b16","series-title":"Pediatrics","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1542\/peds.20.1.23","article-title":"Idiopathic hyponatremia in an infant with diffuse cerebral damage.","volume":"20","author":"McCrory","year":"1957"},{"key":"b17","series-title":"Trans Assoc Am Physicians","first-page":"57","article-title":"A salt-wasting syndrome associated with cerebral disease.","volume":"63","author":"Peters","year":"1950"},{"key":"b18","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1001\/archneur.1964.00460180061006","article-title":"Hyponatremia with herpes simplex encephalitis. Possible relationship of limbic lesions and ADH secretion.","volume":"10","author":"Rovit","year":"1964"},{"key":"b19","series-title":"Am J Med","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1016\/0002-9343(57)90224-3","article-title":"A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone.","volume":"23","author":"Schwartz","year":"1957"},{"key":"b20","series-title":"Arch Int Med","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1001\/archinte.1952.00240090076007","article-title":"Role of the central nervous system in metabolism of electrolytes and water.","volume":"90","author":"Welt","year":"1952"},{"key":"b21","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1001\/archneur.1960.03840100029005","article-title":"Hyponatremia following craniotomy.","volume":"2","author":"Wise","year":"1960"},{"key":"b22","series-title":"Neurosurgery","first-page":"412","article-title":"Syndrome of inappropriate antidiuretic hormone secretion after spontaneous subarachnoid hemorrhage: a reversible cause of clinical deterioration.","volume":"3","author":"Wise","year":"1978"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/6\/article-p938.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/6\/article-p938.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/55\/6\/article-p938.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T12:28:41Z","timestamp":1658665721000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/55\/6\/article-p938.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,12]]},"references-count":22,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1981.55.6.0938","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1981,12]]}}}