{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T07:49:28Z","timestamp":1791100168974,"version":"4.1.0"},"reference-count":35,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1982,6]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Two patients with intractable pain of the head and neck due to cancer underwent trigeminal tractotomy and rhizotomy of the ninth and 10th cranial nerves, as well as an upper cervical dorsal rhizotomy. Postoperatively, cutaneous analgesia was present ipsilaterally in peripheral portions of the face and the neck, but paramedian facial regions and the oral mucosa were hypalgesic. The procedures had no significant effect on dental pain perception in these patients, as tested electrically and thermally. These results are similar to those in recent reports of dental sensation after trigeminal tractotomy in animals. The results raise questions about the validity of the commonly espoused hypothesis that trigeminal nucleus caudalis is the exclusive locus for processing of orofacial nociceptive information. The findings are consistent with the idea that the entire spinal trigeminal nucleus serves as a site for integration of painrelated information from orofacial structures that are supplied by afferent fibers in the fifth, seventh, ninth, and 10th cranial nerves and the upper cervical nerve roots.<\/jats:p>","DOI":"10.3171\/jns.1982.56.6.0812","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:13:51Z","timestamp":1241799231000},"page":"812-818","source":"Crossref","is-referenced-by-count":61,"title":["Effect of trigeminal tractotomy on dental sensation in humans"],"prefix":"10.3171","volume":"56","author":[{"given":"Ronald F.","family":"Young","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Trans Am Neurol Assoc","first-page":"129","article-title":"The descending trigeminal tract as a mechanism for intersegmental sensory facilitation.","volume":"95","author":"Denny-Brown","year":"1970"},{"key":"b2","series-title":"Brain","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1093\/brain\/96.4.783","article-title":"The function of the descending root of the fifth nerve.","volume":"96","author":"Denny-Brown","year":"1973"},{"key":"b3","series-title":"Acta Physiol Scand","first-page":"1","article-title":"Functional organization in the main sensory trigeminal nucleus and in the rostral subdivision of the nucleus of the spinal trigeminal tract in the cat.","volume":"59","author":"Eisenman","year":"1963"},{"key":"b4","series-title":"Arch Neurol Psychiatry","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1001\/archneurpsyc.1949.02310160113007","article-title":"Late changes in the brain stem following trigeminal tractotomy.","volume":"62","author":"Erskine","year":"1949"},{"key":"b5","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1136\/jnnp.12.4.297","article-title":"Intramedullary trigeminal tractotomy and its place in treatment of facial pain.","volume":"12","author":"Falconer","year":"1949"},{"key":"b6","series-title":"Clin Neurosurg","first-page":"69","article-title":"Discussion on trigeminal tractotomy.","volume":"2","author":"Grant","year":"1955"},{"key":"b7","series-title":"Arch Neurol Psychiatry","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1001\/archneurpsyc.1940.02280030072007","article-title":"Section of the descending spinal root of the fifth cranial nerve.","volume":"43","author":"Grant","year":"1940"},{"key":"b8","series-title":"Arch Oral Biol","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/0003-9969(73)90049-6","article-title":"An electrophysiological study of the central connections of primary afferent nerve fibres from the dental pulp in the cat.","volume":"18","author":"Greenwood","year":"1973"},{"key":"b9","series-title":"Endodontic Practice","first-page":"64","author":"Grossman","year":"1974"},{"key":"b10","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3171\/jns.1976.44.1.0021","article-title":"Medical modification of sensation.","volume":"44","author":"Hodge","year":"1976"},{"key":"b11","series-title":"J Neurophysiol","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1152\/jn.1981.45.2.173","article-title":"Functional properties of neurons in cat trigeminal subnucleus caudalis (medullary dorsal horn). 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