{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T16:30:55Z","timestamp":1790094655645,"version":"4.0.1"},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1982,12]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors have analyzed retrospectively a series of 288 consecutive patients with severe head injury observed between January, 1977, and May, 1980. Seventy-three patients were excluded as not being compatible with those of the International Data Bank. The remaining 215 patients complied with the definition of coma given by Jennett. All patients, after appropriate cardiopulmonary resuscitation, diagnostic measures, and, when required, surgical treatment, were managed in the Neurosurgical Intensive Care Unit with endotracheal intubation, controlled hyperventilation, mild dehydration, dexamethasone in standard doses, and sedation. The mortality rate was 39.5%. Of the survivors, 59.2% made a good recovery, 18.4% remained moderately disabled, 6.1% were severely disabled, and 1.5% were in a persistent vegetative state. The most reliable predictive criteria were: absence of brain-stem reflexes, neurological status, abnormal motor patterns, arterial hypotension, and presence of mass lesions. It is concluded that no sign has an absolute prognostic value when considered independently of its time course.<\/jats:p>","DOI":"10.3171\/jns.1982.57.6.0779","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T13:59:57Z","timestamp":1241791197000},"page":"779-783","source":"Crossref","is-referenced-by-count":107,"title":["Prognosis of severe head injuries"],"prefix":"10.3171","volume":"57","author":[{"given":"Anna","family":"Levati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L.","family":"Farina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Vecchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Rossanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marialuisa B.","family":"Marrubini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"491","DOI":"10.3171\/jns.1977.47.4.0491","article-title":"The outcome from severe head injury with early diagnosis and intensive management.","volume":"47","author":"Becker","year":"1977"},{"key":"b2","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"625","DOI":"10.3171\/jns.1980.52.5.0625","article-title":"Prolonged posttraumatic unconsciousness. 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A practical scale.","volume":"1","author":"Jennett","year":"1975"},{"key":"b4","series-title":"Lancet","first-page":"1031","article-title":"Predicting outcome in individual patients after head injury.","volume":"1","author":"Jennett","year":"1976"},{"key":"b5","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1227\/00006123-197904000-00001","article-title":"Prognosis of patients with severe head injury.","volume":"4","author":"Jennett","year":"1979"},{"key":"b6","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"503","DOI":"10.3171\/jns.1977.47.4.0503","article-title":"Significance of intracranial hypertension in severe head injury.","volume":"47","author":"Miller","year":"1977"},{"key":"b7","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3171\/jns.1981.54.3.0289","article-title":"Further experience in the management of severe head injury.","volume":"54","author":"Miller","year":"1981"},{"key":"b8","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1136\/jnnp.38.2.149","article-title":"Clinical course and prognosis of acute post-traumatic coma.","volume":"38","author":"Pazzaglia","year":"1975"},{"key":"b9","series-title":"The Diagnosis of Stupor and Coma","first-page":"44","author":"Plum","year":"1980"},{"key":"b10","series-title":"J Neurosurg Sci","first-page":"265","article-title":"Role of automatic ventilation in treatment of severe head injuries.","volume":"17","author":"Rossanda","year":"1973"},{"key":"b11","series-title":"Lancet","first-page":"81","article-title":"Assessment of coma and impaired consciousness. A practical scale.","volume":"2","author":"Teasdale","year":"1974"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/57\/6\/article-p779.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/57\/6\/article-p779.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/57\/6\/article-p779.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T04:59:28Z","timestamp":1668315568000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/57\/6\/article-p779.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,12]]},"references-count":11,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1982.57.6.0779","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1982,12]]}}}