{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T04:13:27Z","timestamp":1759032807915},"reference-count":22,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors produced occlusion of the middle cerebral artery (MCA) trunk in dogs by two methods: silicone cylinder embolization and trapping. Comparative analyses of the clinicopathological features in these models, extending from the acute to chronic stage, were performed.<\/jats:p>\n<jats:p content-type=\"fine-print\">Within 24 hours after embolization, the brain exhibited swelling without macroscopic infarction. Microangiograms revealed impaired filling in the deep areas of the brain with midline shift. At 4 to 7 days after embolization, the animals showed major neurological deficits, evident deep cerebral infarction, and poorly perfused areas in the deep cerebrum with prominent midline shift. At 3 to 4 weeks after embolization, the neurological deficits improved and the affected regions showed cavities or localized lesions. Microangiograms demonstrated hypervascular areas with abnormal vessels in the affected cerebrum. On the other hand, trapping of the MCA trunk produced mild neurological deficits, although there was no evidence of macroscopic lesions or impairment of filling. This study shows that silicone cylinder embolization in the MCA trunk produces a reliable and reproducible deep cerebral infarction in dogs.<\/jats:p>","DOI":"10.3171\/jns.1983.58.4.0492","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T18:23:41Z","timestamp":1241807021000},"page":"492-499","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of middle cerebral artery trunk occlusion by silicone cylinder embolization and by trapping"],"prefix":"10.3171","volume":"58","author":[{"given":"Yoshikazu","family":"Okada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Shima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noboru","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Uozumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1161\/01.STR.6.4.387","article-title":"Artificial embolization of the middle cerebral artery in primates.","volume":"6","author":"Bremer","year":"1975"},{"key":"b2","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1161\/01.STR.1.6.439","article-title":"Temporary occlusion of the middle cerebral artery in the monkey: clinical and pathological observations.","volume":"1","author":"Crowell","year":"1970"},{"key":"b3","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1212\/WNL.21.7.710","article-title":"Angiographic and microangiographic observations in experimental cerebral infarction.","volume":"21","author":"Crowell","year":"1971"},{"key":"b4","series-title":"Am J Anat","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1002\/aja.1001050303","article-title":"Intracranial and extracranial circulations in the dog: anatomic and angiographic studies.","volume":"105","author":"de la Torre","year":"1959"},{"key":"b5","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1148\/125.2.393","article-title":"The capacity for computed tomography diagnosis of cerebral infarction.","volume":"125","author":"Drayer","year":"1977"},{"key":"b6","series-title":"J Neuropathol Exp Neurol","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1097\/00005072-197407000-00007","article-title":"Cerebral infarction. 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