{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T13:15:31Z","timestamp":1721913331382},"reference-count":22,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Regional cerebral blood flow (rCBF), sensory evoked potentials (SEP), and intracranial pressure (ICP) were investigated in dogs with focal cerebral ischemia produced by a silicone cylinder embolus in the middle cerebral artery (MCA) trunk as compared to that produced by trapping the same vessel. These variables were measured at intervals of 1 hour for a period of 6 hours after MCA occlusion.<\/jats:p>\n<jats:p content-type=\"fine-print\">In the embolized animals, rCBF decreased most extensively at the basal ganglia, from a control level of 53.9 \u00b1 3.9 (mean \u00b1 SE) to 21.5 \u00b1 2.7 ml\/100 gm\/min at the 6th hour. Sensory evoked potentials decreased progressively from the resting level of 100% to 53.0% \u00b1 7.2% at the 3rd hour. Intracranial pressure, measured by epidural pressure on the occluded side, increased rapidly during the first 3 hours, from 10.6 \u00b1 0.3 to about 30 cm H<jats:sub>2<\/jats:sub>O.<\/jats:p>\n<jats:p content-type=\"fine-print\">In the animals with trapping, the decreases in rCBF and declines of SEP were significantly less than those in the embolized animals, and no evident brain swelling was observed. This study demonstrates that MCA trunk occlusion by silicone cylinder embolization produces a more marked decrease in deep CBF, with diminution of SEP and increase in ICP, than that produced by trapping.<\/jats:p>","DOI":"10.3171\/jns.1983.58.4.0500","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T18:23:41Z","timestamp":1241807021000},"page":"500-507","source":"Crossref","is-referenced-by-count":9,"title":["Regional cerebral blood flow, sensory evoked potentials, and intracranial pressure in dogs with MCA occlusion by embolization or trapping"],"prefix":"10.3171","volume":"58","author":[{"given":"Yoshikazu","family":"Okada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Shima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuo","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Uozumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1161\/01.STR.8.4.487","article-title":"Evoked potential changes during brain retraction in dogs.","volume":"8","author":"Bennett","year":"1977"},{"key":"b2","series-title":"Acta Neurol Scand","first-page":"1","article-title":"Cerebral hemodynamics in carotid surgery.","volume":"49","author":"Boysen","year":"1973"},{"key":"b3","series-title":"Exp Neurol","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/0014-4886(74)90112-5","article-title":"Relationship between the cortical evoked potential and local cortical blood flow following acute middle cerebral artery occlusion in the baboon.","volume":"45","author":"Branston","year":"1974"},{"key":"b4","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1161\/01.STR.3.2.123","article-title":"Intracranial pressure gradients associated with experimental cerebral embolism.","volume":"3","author":"Brock","year":"1972"},{"key":"b5","series-title":"Exp Neurol","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/0014-4886(71)90098-7","article-title":"Recovery following sensorimotor cortical damage: evoked potentials, brain stimulation and motor control.","volume":"33","author":"Glassmann","year":"1971"},{"key":"b6","series-title":"Circ Res","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1161\/01.RES.36.1.18","article-title":"Comparison of 85Krypton and 133Xenon cerebral blood flow measurements before, during, and following focal, incomplete ischemia in the squirrel monkey.","volume":"36","author":"Hanson","year":"1975"},{"key":"b7","series-title":"Arch Neurol Psychiatry","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1001\/archneurpsyc.1951.02320070040002","article-title":"Occlusion of the middle cerebral artery. 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